Hormone therapy may boost sex life in early menopause, study hopes

NCT ID NCT05890417

Completed Knowledge-focused Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 30, 2026 · Updated 3 times

Summary

This study follows 135 women with premature ovarian failure (early menopause) to see if hormone replacement therapy improves their sexual quality of life. Participants fill out questionnaires about sexual function and well-being before starting treatment and again 6 months later. The goal is to understand whether hormone therapy helps with desire, arousal, lubrication, orgasm, satisfaction, and pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hormone replacement therapy
What this could lead to: If successful, this could show that hormone replacement therapy improves sexual quality of life for women with premature ovarian failure.
What could go wrong: This is an observational study with no control group, so results may not prove cause and effect. It is small (135 participants) and only follows women for 6 months.

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Conditions

The condition(s) this trial relates to.

premature menopause primary ovarian failure Sexuality

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PREMATURE OVARIAN FAILURE

Contacts and locations

Locations

AP-HP_Hôpital Saint Antoine

Paris, France
CHU Bordeaux

Bordeaux, France

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