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116076 trials found · Page 5084 of 5804
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Nerve blocks may cut opioid use in newborn cleft lip repair
Knowledge-focused CompletedIn retrospective data search the investigators will identified the cumulative consumption of opioid analgesics during surgery and 24 hours after surgery in neonate with cleft lips who underwent primary cleft lip repair surgery.
Sponsor: Brno University Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:22 UTC
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Blood marker tracking may sharpen liver cancer prognosis
Knowledge-focused CompletedTo evaluate whether tracking changes in key blood markers over time, together with clinical features, can improve the prediction of outcomes in patients with hepatocellular carcinoma (HCC). By developing a trajectory-based prognostic model, we aim to provide more accurate risk as…
Sponsor: Xu Yong, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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400 patients studied to uncover clues about neovascular glaucoma
Knowledge-focused CompletedThe goal of this observational study is to explore the clinical characteristics of patients with neovascular glaucoma (NVG), and to analyze the relationship between NVG and various underlying diseases, ocular conditions, lifestyle, inflammatory markers, and treatment response. To…
Sponsor: Zhongnan Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:26 UTC
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MS and fertility: new study looks at ovarian health in young women
Knowledge-focused CompletedCONTEXT A desire for pregnancy is common in young patients with multiple sclerosis (MS). The impact of MS on women fertility is debated, and the impact of disease-modifying therapies (DMTs) on fertility is not well known. Antimüllerian hormone (AMH) is a representative biomarker …
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:31 UTC
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Switzerland launches massive rare disease registry to unlock secrets of thousands of conditions
Knowledge-focused Recruiting nowThe SRDR is a national registry that records rare diseases in people of any age who live in Switzerland. It serves as a platform for scientists, health professionals, affected people, and politicians.The SRDR aims to collect epidemiological data on rare diseases, and data on chan…
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Music therapy hits the right note for stroke rehab?
Symptom relief CompletedMusic listening intervention has made great strides in improving the condition of stroke survivors. Thus, this research explores the effects of music listening intervention on post-stroke survivors during rehabilitation by using P. Ramlee songs.
Phase: NA • Sponsor: University of Malaya • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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New online tool aims to ease depression in hispanic stroke caregivers
Symptom relief CompletedThis research study will test a problem-solving intervention for Spanish-speaking stroke caregivers that will be delivered over the telephone and online via the previously developed and nationally available Spanish version of the RESCUE website. The investigators will adapt their…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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ICU antibiotic dosing: what really matters?
Knowledge-focused CompletedThe population of these monocentric and retrospective study includes patients hospitalized in one of the critical care services of Nîmes' community hospital. The objective is to determine the key factors that lead to satisfactory beta-lactams serum concentrations in critically i…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Can inflammatory clues predict kidney damage in ICU patients?
Knowledge-focused Recruiting nowAcute kidney injury (AKI) affects more than 50% of patients admitted to the intensive care unit. The most common underlying cause is sepsis. Severe AKI in combination with sepsis is associated with high mortality. The mechanisms for sepsis-induced AKI are largely unknown. Our hyp…
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Experimental immune therapy takes aim at Hard-to-Treat cancers
Disease control CompletedAlkaline phosphatase (ALP) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphates at alkaline pH values. As one of the earliest discovered oncofetal antigens, ALP has emerged as a significant biomarker for various malignant tumors, such as ovarian cancer, br…
Phase: PHASE1, PHASE2 • Sponsor: Xinqiao Hospital of Chongqing • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Can we predict who gets pain relief from nerve zapping?
Knowledge-focused CompletedThis retrospective cohort study will review medical records of patients treated with intercostal nerve radiofrequency for intercostal neuralgia. The goal is to identify patient and clinical factors that are associated with treatment success after the procedure. Outcomes will be a…
Sponsor: Mersin University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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E-Cigarettes vs. diabetes: a safer smoke?
Knowledge-focused CompletedIndividuals with T2DM who smoke have higher risks of cardiovascular disease and other complications. Many people consider e-cigarette as a "harm-reduction" alternatives to combustible cigarettes, but it is not clear whether switching to e-cigarettes improves health outcomes in pa…
Sponsor: Samsung Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Can a talking therapy ease the burden on cancer caregivers?
Symptom relief CompletedThis research study is evaluating the impact of a psychological intervention on the quality of life and mood of caregivers of patients undergoing stem cell transplant.
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Pneumonia biomarker hunt completed in 272 patients
Knowledge-focused CompletedTo identifying biomarkers in patients with pneumonia
Sponsor: Chongqing Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Dialysis fistulas: are they being used two years later?
Knowledge-focused OngoingArteriovenous fistulas (AVFs) are the standard for dialysis sessions. However, this usually requires surgery before dialysis can begin. Given this pre-operative approach, the investigators evaluate the two-year utilization rate of AVFs and seek to understand why they are still no…
Sponsor: University Paul Sabatier of Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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10,000 seniors studied to predict fatty liver dangers
Knowledge-focused CompletedThis is a single-center, retrospective cohort study based on data from the Nanjing Elderly Steatotic Liver Disease Cohort. The study aims to investigate risk factors for liver-related adverse outcomes (including significant fibrosis, advanced fibrosis, cirrhosis, hepatocellular c…
Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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School tech program aims to teach teens emotional smarts
Symptom relief CompletedThe purpose of the study is to develop adolescents' social-emotional abilities to foster their personal and social responsibility, as well as their well-being, by means of a school-based intervention that addresses students, teachers and parents who participate in a social-emotio…
Phase: NA • Sponsor: University of Valencia • Aim: Symptom relief
Last updated Jun 27, 2026 12:26 UTC
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Scientists map immune landscape of liver tumors to predict cancer return
Knowledge-focused OngoingCorrelation and Heterogeneity of the Immune Microenvironment and Histopathological Growth Patterns in Resectable Colorectal Cancer Liver Metastases
Sponsor: Meng Qiu • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Common bladder drug may ease kidney stone surgery
Symptom relief CompletedThe aim of this study is to evaluate whether there is a difference in the passage rate of the ureteral access sheath between patients who used mirabegron (a beta-3 receptor agonist) for overactive bladder and those who underwent retrograde intrarenal surgery for kidney stones, an…
Sponsor: Ankara Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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New Two-Tool scope technique aims to remove stuck swallowed objects without surgery
Disease control CompletedWe describe a single-center, retrospective case series (n = 10) for the utilization of dual instruments to extract foreign body at physiological narrowing. Foreign bodies that failed to remove with a single instrument or located in physiological narrowing into the duodenal bulb o…
Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC