Experimental cancer drug AUR106 tested in humans for first time

NCT ID NCT05861947

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tested an experimental drug called AUR106 in 21 adults with advanced solid tumors (lung, stomach, bladder, kidney, colon, or esophageal cancer) that had come back or spread. The main goals were to check safety, find the right dose, and see how the drug moves through the body. The study was terminated early, so full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AUR106 (an experimental drug taken by mouth)

What this could lead to

If successful, this could point toward a new treatment option for certain advanced cancers that have stopped responding to standard therapies.

What could go wrong

This is a very early, small Phase 1 trial (only 21 patients) focused on safety and dosing, not effectiveness. The trial was terminated, so results may be incomplete.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer colon carcinoma colonic neoplasm esophageal cancer Esophageal Neoplasms gastric cancer gastric neoplasm kidney cancer non-small cell lung carcinoma Recurrence transitional cell carcinoma urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • All India Institute of Medical Sciences

    Bhubaneswar, Odisha, 751019, India

  • Kiran Multi Super Specialty Hospital

    Surat, Gujarat, 395004, India

  • Moraya Multispeciality Hospital (Ashwin Medical Foundations)

    Pune, Maharasthra, 411033, India

  • Omega Hospital

    Visakhapatnam, Andhra Pradesh, 530040, India

  • Sankalp Speciality Hospital

    Nashik, Maharashtra, 422009, India

  • Unique Hospital Multispeciality and Research Institute

    Surat, Gujarat, 395002, India