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116076 trials found · Page 5069 of 5804
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Glowing shoes may help seniors stay steady
Symptom relief CompletedObjectives: The aim of this study is to investigate the effects of a light-up shoe that creates visual stimuli on balance, walking and fall risk in geriatric individuals. Methods: Fifty-two geriatric individuals who agreed to participate in this study were assessed under four co…
Phase: NA • Sponsor: Kirsehir Ahi Evran Universitesi • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Should cancer patients get antibiotics for a dubious c. diff test? small trial seeks answers
Disease control CompletedThis study will randomized hematology oncology patients with active diarrhea and a NAAT positive/toxin EIA negative to either 14 days of oral vancomycin capsules or placebo. The study is designed to include 30 patients (15 per arm). Outcomes will include C. difficile load using …
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Heart drug entresto may double as diabetes treatment, small study hints
Knowledge-focused TerminatedType 2 diabetes is common, increases in prevalence with age, and patients with diabetes have an increased risk of cardiovascular disease. A relatively new cardiovascular medication currently used for the treatment of heart failure in the United States inhibits an enzyme that brea…
Phase: PHASE3 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:02 UTC
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Can a good Night's sleep ease teen anxiety?
Knowledge-focused CompletedThe current study aims to deepen understanding of the symptom dimension of negative overgeneralization in anxiety. Specifically, the study examines the malleability of memory processes that are known to occur during sleep that may underlie negative overgeneralization.
Phase: NA • Sponsor: Florida International University • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:35 UTC
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Can a puff of oxygen during exercise ease breathlessness for IPF patients?
Symptom relief CompletedIdiopathic pulmonary fibrosis (IPF) is a disease characterised with significant morbidity and poor prognosis. Dyspnoea and impaired exercise capacity are very common manifestations of the disease, and result in significant impairment of patients' quality of life. Although hypoxem…
Phase: NA • Sponsor: George Papanicolaou Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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Major study maps rare nerve condition to improve care
Knowledge-focused CompletedCauda equina syndrome is a potentially devastating condition caused by compression of the cauda equina nerve roots. This can result in bowel, bladder and sexual dysfunction plus lower limb weakness, numbness, and pain. Cauda equina syndrome occurs infrequently but has serious pot…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Bolus vs. continuous: which pain pump works best after surgery?
Symptom relief Recruiting nowThe goal of the study is to compare continuous infusions and scheduled bolus infusions for peripheral nerve blocks and their effect on post-surgical pain.
Phase: PHASE4 • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Pulse oximeter trick may speed up nerve block checks
Knowledge-focused CompletedPeripheral nerve blocks are increasingly used in lower extremity surgery as an alternative to general anesthesia. However, traditional methods used to assess block success, such as sensory and motor testing, are subjective, time-consuming, and dependent on patient cooperation. T…
Phase: NA • Sponsor: University of Gaziantep • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Sticky tape boosts stroke recovery? small trial shows promise
Symptom relief CompletedThis randomized, controlled clinical trial was conducted to evaluate the effects of kinesio taping on upper extremity motor recovery in patients with acute ischemic stroke who presented with flaccid muscle tone. Twenty-six adults were randomly assigned to either a kinesio taping …
Phase: NA • Sponsor: Koç University • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Scientists hunt for hidden mutations behind polycystic kidney disease
Knowledge-focused ENROLLING_BY_INVITATIONThis study will analyze the germline and somatic mutations underlying the development of ADPKD in order to better understand the genetic mechanism responsible for the cystic transformation. Once identified, these mutations could help us understand better the mechanism leading to …
Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Speed test: new PCR method outruns standard lab for abdominal infections
Knowledge-focused CompletedWith this study, the investigators want to determine whether a fast identification of microorganisms causing intra-abdominal infections in patients with suspected hollow organ perforation or peritonitis is possible using a multiplex PCR system (Unyvero A50), a method that allows …
Sponsor: University of Göttingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Brain scan could spot early dementia clues
Knowledge-focused Recruiting nowThe investigators aim to use the new PET radioligand, 18F-MK-6240, to detect tau pathology in cognitive healthy and mild cognitive impairment (MCI) elders. The investigators will then examine the interactions between differential tau burden and performance on cognitive tasks, fun…
Sponsor: Yaakov Stern • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Massive blood pressure registry aims to personalize care
Knowledge-focused Recruiting nowThe problem of the quality of primary health care medical system for patients with arterial hypertension is acute for the investigator's country, as these diseases are the most common and cause the high mortality of the population. The concept of "quality of primary health care …
Sponsor: National Medical Research Center for Cardiology, Ministry of Health of Russian Federation • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Mind over lyme: do expectations shape recovery?
Knowledge-focused Recruiting nowThe investigators will focus on pretreatment expectations of patients with early Lyme disease manifested as erythema migrans with the aim of assessing the association between pretreatment expectations quantified with a questionnaire and treatment outcome quantified with the prese…
Phase: NA • Sponsor: University Medical Centre Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Lung ultrasound may replace invasive monitors for fluid management in surgery
Knowledge-focused CompletedThe possibility of exploring the lungs by lung ultrasound, a non-invasive tool, is becoming increasingly popular for anesthesiologists. Recently, Lichtenstein has described the FALLS protocol (Fluid Administration Limited by Lung Sonography) which uses the potential of pulmonary …
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Could oral cancer surgery become a Same-Day procedure?
Disease control Recruiting nowThis is a single-center pilot study of open-label, non-randomized interventional research based on the outpatient management of 30 patients with T1-N0 or T2-N0 cancer in the oral cavity or oropharynx.
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Breathing new life: exercise program shows promise for stiff spine patients
Symptom relief CompletedThis prospective pilot study aims to evaluate the efficacy of a structured 8-week multimodal pulmonary rehabilitation (PR) program specifically designed for patients with radiographic axial spondyloarthritis (r-axSpA). The study assesses the impact of a composite intervention inc…
Phase: NA • Sponsor: Balikesir University • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Massive study aims to unlock secrets of immune system diseases
Knowledge-focused Recruiting nowBackground: Primary immunodeficiency disorders, or PIDs, are diseases that weaken the immune system. This makes it easier for a person to get sick. Some PIDs are mild and may not be diagnosed until later in life. Other kinds are severe and can be identified shortly after birth. …
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
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Can a friend be your kidney donor champion? new program tested
Knowledge-focused CompletedThe Live Donor Champion Program is a clinical education program offered to patients placed on the waitlist for kidney transplantation at the Johns Hopkins Comprehensive Transplant Center. The goal of the program is to increase patient knowledge regarding end stage renal disease, …
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Sitting less might help older women age better
Knowledge-focused CompletedEpidemiological findings indicate that older adults do not meet physical activity (PA) guidelines \& spend up to 11 hrs/day sitting. Given the high prevalence of sedentary behavior (SB), the higher chronic disease risk in this population, \& the age-associated challenges of meeti…
Phase: NA • Sponsor: University of California, San Diego • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC