Cholesterol drug may alter flu Shot's power

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Able to understand and give informed consent. * Age 18-50 years. * Women of childbearing potential must agree to use effective birth control for the first 3 months of the study. A negative urine pregnancy test must be documented prior to vaccination. Exclusion Criteria: * History of allergy or serious adverse reaction, including Guillain-Barré syndrome, to a vaccine or vaccine products. * History of a medical condition resulting in impaired immunity such as active solid tumors, leukemia, lymphoma, use of immunosuppressive drugs, chemotherapy, or radiation therapy. Persons with previous skin cancers or cured non-lymphatic tumors are not excluded from the study. * History of HIV, Hepatitis B, or Hepatitis C infection. * Chronic clinically significant medical problems that could be considered active or unstable (i.e. diagnosed within the past 3 months or requiring a change in medication within the past 3 months). This includes (but is not limited to): 1. Insulin-dependent diabetes 2. Severe heart disease (including arrhythmias) 3. Severe lung disease 4. Severe liver disease 5. Severe kidney disease 6. Severe hypertension: defined as life-threatening consequences (e.g., malignant hypertension, transient or permanent neurologic deficit). * BMI \> 30 * Current or previous use of statins or any other lipid-lowering drug. * Pregnancy or breastfeeding or plans to become pregnant in the first 3 months of study participation. * History of influenza infection within the same influenza season. * Receipt of blood products or immune globulin products within the prior 3 months. * History of excessive alcohol consumption, drug use, psychiatric conditions, social conditions, or occupational conditions that in the opinion of the investigator would preclude compliance with the trial. * Receipt of any live vaccines 30 days before or plans to receive any live vaccines 30 days after vaccination. * Receipt of any inactivated vaccines 14 days before or plans to receive any inactivated vaccines 14 days after vaccination. For participants randomized to the statin therapy + QIV group: * The participant is currently taking any medication that has known interactions with statin therapy. * History of renal or hepatic impairment. * Abnormal Safety lab results \>1.5 upper limit normal (ULN)