Empty bladder may ease prostate radiation prep, trial suggests

NCT ID NCT06037863

Ongoing Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests whether having an empty bladder before CT simulation for prostate cancer radiation therapy is better than the usual full bladder. The goal is to see if it reduces urinary symptoms and makes daily treatments more consistent. About 168 men with prostate cancer will be randomly assigned to either empty or full bladder preparation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bladder filling procedure
What this could lead to: If it works, this could show that an empty bladder is just as good or better for radiation planning, reducing patient discomfort and treatment delays.
What could go wrong: This is a small, early-stage trial (168 participants) comparing two preparation methods, not a new treatment. Results may not change standard practice or apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CARCINOMA

Contacts and locations

Locations

Mayo Clinic Health System in Albert Lea

Albert Lea, Minnesota, 56007, United States
Mayo Clinic Health System-Eau Claire Clinic

Eau Claire, Wisconsin, 54701, United States
Mayo Clinic Health System-Franciscan Healthcare

La Crosse, Wisconsin, 54601, United States
Mayo Clinic Health Systems-Mankato

Mankato, Minnesota, 56001, United States
Mayo Clinic in Arizona

Scottsdale, Arizona, 85259, United States
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

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