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116076 trials found · Page 5027 of 5804
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Heart stent study halted: Real-World data sought
Disease control TerminatedThe objective of this study is to evaluate effectiveness and safety of BIOFREEDOM™ FAMILY stent in the "real world" daily practice as compared with other drug-eluting stents.
Sponsor: Seung-Jung Park • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Ultrasound breakthrough could help ICU patients breathe easier
Knowledge-focused Recruiting nowDeciding the optimal timing for extubation in patients who are mechanically ventilated can be challenging, and traditional weaning predictor tools are not accurate. Recent studies suggest that isolated sonographic assessment of the respiratory and cardiac function (ie diastolic f…
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Talking it out: new study tests emotional writing for chinese cancer patients
Symptom relief CompletedThis study examines the feasibility, cultural-sensitivity, and health effects of the expressive helping intervention by conducting a single-arm trial with Chinese-speaking cancer patients and survivors.
Phase: NA • Sponsor: New York University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Blood loss after hip break may rob seniors of independence
Knowledge-focused CompletedFracture of the upper extremity of the femur is a condition whose frequency increases with age. It is a serious disease, with multiple consequences such as a decrease in life expectancy, quality of life and patient autonomy. In this observational study, the investigators wish to …
Sponsor: Centre Hospitalier Departemental Vendee • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:18 UTC
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Fatty liver drug trial halted early: what we know
Disease control TerminatedThis Phase 1/2 study will evaluate safety, efficacy, PK, and PD of FT-4101 as a single agent in overweight/obese subjects with NASH. The study may be conducted in up to 2 dosing cohorts.
Phase: PHASE1, PHASE2 • Sponsor: Forma Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Ovarian cancer immune cells under microscope in terminated study
Knowledge-focused TerminatedThis is a monocenter, interventional, non-randomized study among women patients with an ovarian or tubal cancer who will receive a surgery or adjuvant chemotherapy treatment, or a neo-adjuvant chemotherapy then surgery +/- adjuvant chemotherapy. The planned interventions are coll…
Phase: NA • Sponsor: Centre Oscar Lambret • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Could a simple breath test make anesthesia safer for kids?
Knowledge-focused CompletedProtective ventilation decreased morbidity and mortality in adults' patients and is now a standard of care in intensive care unit and in anesthesiology. In children, there is no evidence in the literature to recommend protective ventilation during anaesthesia. Moreover the ratio …
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:24 UTC
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Blood tests and surveys may predict cancer treatment success
Knowledge-focused CompletedThis is a prospective study addressing the challenge of predicting disease progression and/or recurrence in patients diagnosed with metastatic colorectal, pancreatobiliary, or esophagogastric cancer that are receiving anti-cancer therapy.
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Gut bacteria drug shows promise against blood disorder
Disease control CompletedThis trial studies how well rifaximin works in treating patients with monoclonal gammopathy. Antibiotics, such as rifaximin, may help to kill bacteria in the intestines and reduce the abnormal protein or cells in patients with monoclonal gammopathy.
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Community leaders could be key to better eating habits
Knowledge-focused CompletedNutritional factors are responsible for 10% of the global health burden. In Israel, 31% of Jewish women and 52% of Arab women are obese. It is predicted that this generation will see increased cardiovascular disease (CVD) and decreased life expectancy. Sustained lifestyle changes…
Phase: NA • Sponsor: Hadassah Medical Organization • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Could a blood pressure drug curb impulsive behaviors in Parkinson's?
Symptom relief CompletedNoradrenergic system is involved in impulsivity in the general population and is altered in Parkinson's disease (PD) in the early stages of the disease. Thus, targeting this system could be of interest in impulse control disorder (ICD). Acting on the noradrenergic system is possi…
Phase: PHASE2 • Sponsor: Hospices Civils de Lyon • Aim: Symptom relief
Last updated Jun 26, 2026 13:22 UTC
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Can a stomach stent predict who gets better? small study tests new approach for gastroparesis
Knowledge-focused TerminatedThis is a prospective sham study to investigate the role of transpyloric stenting with lumen apposing metal stent (LAMS) as a predictor for clinical response to gastric per-oral endoscopic pyloromyotomy (GPOEM) for refractory gastroparesis. The study hypothesizes that clinical im…
Phase: NA • Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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New imaging method aims to spot dangerous clots
Diagnosis TerminatedThis study aims to investigate a novel positron emission tomography(PET)-probe for imaging of fresh intravascular blood clots in pulmonary embolism (PE) and deep venous thrombosis (DVT).
Phase: PHASE1 • Sponsor: Peter Caravan • Aim: Diagnosis
Last updated Jun 27, 2026 11:03 UTC
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Could a simple breath of ketamine ease Kids' pain in the ER?
Symptom relief CompletedIn the situation when intravenous access is not readily available or unobtainable, sub-dissociative dose ketamine can be administered via intranasal route (IN). The data supporting intranasal route in pediatric patients is somewhat conflicting with regards to the optimum intranas…
Phase: PHASE4 • Sponsor: Antonios Likourezos • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Ear acupuncture may cut Long-Term pain after breast surgery
Symptom relief TerminatedOver the past decade, more and more healthcare professionals are using auriculotherapy as a preventative and effective therapy for pain. This therapy is applied by odontologists, anesthetists, surgeons, etc., to alleviate chronic pain. The effects of auriculotherapy are known in …
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated Jul 18, 2026 00:00 UTC
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Can a quick drug pulse make prostate cancer cells more vulnerable?
Knowledge-focused CompletedThis is a prospective, single-center, two-phase study to assess the efficacy of single pulsed-dose flutamide in creating double strand breaks (DSBs) in prostate cancer within patients receiving central androgen suppression and brachytherapy.
Phase: EARLY_PHASE1 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Teaching the teachers: a new way to spread liver cancer guidelines globally?
Knowledge-focused Recruiting nowThis study evaluates a concept called 'Teaching the Teachers' and whether it is helpful in disseminating guidelines on the national and international levels. "Teaching the Teachers" involves teaching the guidelines to experts who later teach the same guidelines to other radiologi…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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New filling material saves baby teeth that have no permanent replacement
Disease control CompletedThe purpose of this study was to describe the clinical and radiological outcome of root canal treatment with OrthoMTA in primary second molars without successors in which traditional root canal treatment with gutta-percha could not be performed.
Phase: NA • Sponsor: Tokat Gaziosmanpasa University • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Braces pain showdown: researchers test which wire is gentlest
Symptom relief Recruiting nowThree different types of 'archwires' can be used in Orthodontic treatment, wire choice is decided by treating Orthodontist based on professional preference since research shows that all types are equally effective. It is possible that one type of wire engenders more patient disc…
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Scientists create a 'Lipid Library' to unlock secrets of rare cholesterol conditions
Knowledge-focused OngoingThis is a prospective, observational study to establish a repository of samples from patients with extreme lipid phenotypes including but not limited to hyperlipidemia, dyslipidemia, hyperlipoproteinemia, extreme low/high HDL levels and deranged lipoprotein metabolism. The invest…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC