Kidney shield? diabetes drug tested to prevent ICU kidney failure

NCT ID NCT05468203

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether dapagliflozin, a drug used for diabetes and chronic kidney disease, could prevent acute kidney injury in critically ill patients in the intensive care unit (ICU). The trial planned to enroll 3,000 adults but was terminated early after only 51 participants. Patients were randomly assigned to receive either dapagliflozin or a placebo daily for up to 30 days while in the ICU.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Austin Health

    Heidelberg, Victoria, 3084, Australia

  • Epworth Richmond

    Richmond, Victoria, 3121, Australia

  • Grampians Health

    Ballarat, Victoria, 3350, Australia

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