Diabetes drug tested to shield ICU patients from kidney failure

NCT ID NCT05468203

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 26 times

Summary

This study tested whether dapagliflozin, a drug used for diabetes and chronic kidney disease, could prevent acute kidney injury in critically ill patients in the intensive care unit. The trial aimed to enroll 3000 adults but was terminated early after only 51 participants. Participants were randomly assigned to receive either dapagliflozin or a placebo daily for up to 30 days while in the ICU.

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Contacts and locations

Locations

  • Austin Health

    Heidelberg, Victoria, 3084, Australia

  • Epworth Richmond

    Richmond, Victoria, 3121, Australia

  • Grampians Health

    Ballarat, Victoria, 3350, Australia

Conditions

Explore the condition pages connected to this study.