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116076 trials found · Page 5012 of 5804
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Pre-surgery crutch training may stop post-op falls
Prevention Recruiting nowThe purpose of this study is to determine whether preoperative mobility device training is beneficial in reducing incidence of postoperative falls in patients undergoing elective foot and ankle surgery requiring a postoperative period of no weight-bearing.
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Prevention
Last updated Jul 01, 2026 00:00 UTC
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Cancer patients face higher clot risk – new study aims to understand why
Knowledge-focused CompletedThe overall incidence of deep vein thrombosis (DVT) and pulmonary embolism (PE) is 1 per 200 cancer patients, about 5 times higher than in the general population. These events are of crucial importance, since nearly 10% of cancer patients died from thromboembolic events (EVT), m…
Phase: NA • Sponsor: Centre Antoine Lacassagne • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Dental implant showdown: ceramic vs. metal for your smile
Disease control CompletedA post-market, multi-centre, prospective, open, randomized-controlled, non-inferiority clinical study to compare short-term performance and safety of the Straumann PURE 2-piece Ceramic Implant with Straumann Bone Level Implant using a fully digital workflow.
Phase: NA • Sponsor: Institut Straumann AG • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New gum surgery methods tested for better tooth support
Disease control Recruiting nowThree techniques for periodontal reconstruction will be compared, in which marginal access versus apical access will be carried out.
Phase: NA • Sponsor: Universidad de Murcia • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Drug aimed at fixing bone marrow after transplant falls short in early study
Disease control TerminatedPoor graft function (PGF) after allogeneic hematopoietic cell transplantation (allo-HCT) is a misunderstood complication associated with poor outcome and limited therapeutic options. Despite the lack of standardized diagnostic criteria, PGF is commonly defined as follows: one or …
Phase: PHASE2 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Blood filter shows promise for autoimmune patients
Disease control CompletedDocumentation of the safety and effectiveness profile of the CE-labelled immunoadsorber GLOBAFFIN® in clinical routine according to their intended use.
Phase: NA • Sponsor: Fresenius Medical Care Deutschland GmbH • Aim: Disease control
Last updated Jun 26, 2026 14:18 UTC
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Can leg muscle metabolism explain fatigue in older adults with HIV?
Knowledge-focused Recruiting nowThe investigators are studying whether metabolic abnormalities in calf (leg) muscle in older people with and others without HIV are associated with decreased abilities to exercise.
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Blood test may predict heart attack risk during surgery
Knowledge-focused Recruiting nowThe team is investigating whether N-terminal pro B-type natriuretic peptide (NT-proBNP) and other cardiac markers are useful for predicting outcomes for patients undergoing vascular surgery. By measuring NT-proBNP before and after surgery, the investigators may be able to determi…
Sponsor: Norfolk and Norwich University Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Gut bacteria may hold key to safer cancer immunotherapy
Knowledge-focused Recruiting nowThis is a single-center, investigator-initiated, non-interventional study evaluating the role of the intestinal microbiome and autoimmune panels as a predictor for developing ≥ Grade 2 CTCAE v5.0 immune-related adverse event (irAE) and/or requiring systemic immunosuppression for …
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Experimental drug K0706 tested for lewy body dementia
Symptom relief TerminatedThis study evaluates the safety and tolerability of treatment with K0706 in Dementia with Lewy Bodies (DLB). The hypothesis is that K0706 will be safe and tolerable and that this drug will alter CSF and plasma biomarkers in DLB. Clinical assessments of cognitive, behavioral and …
Phase: PHASE2 • Sponsor: Georgetown University • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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Bone cement safety confirmed in Real-World spine surgery study
Disease control Recruiting nowA Post-Market Clinical Follow-Up (PMCF) Study to collect clinical data on safety and performance of all TEKNIMED Spine range of products: SPINEFIX, HIGH V+, OPACITY+ and F20 bone cements and mixing and injection systems, and all their private labels. TEKNIMED bone cements are le…
Sponsor: Teknimed • Aim: Disease control
Last updated Jun 26, 2026 14:39 UTC
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New MRI scans aim to unlock secrets of lung disease and long COVID
Knowledge-focused TerminatedLung magnetic resonance imaging (MRI) with proton and inhaled inert gases has demonstrated a clinical ability to provide valuable structural and functional information in lung disease. Advances in lung MRI methods have led to the STH department handling clinical imaging referrals…
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Cancer drug trial stopped early: only 5 patients enrolled
Disease control TerminatedA non randomized, unblinded, open label phase 2 study to investigate the efficacy of pembrolizumab in patients with relapsed/refractory diffuse large B cell lymphoma (DLBCL) with PD-L1 genetic alterations
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New implant method may offer better fit for lower dentures
Disease control OngoingH0: "Within the first year post-placement, four interforaminally placed, immediately loaded 2.4 mm narrow-diameter one-piece TiZr implants with miniaturized stud-type attachments show improved patient-reported outcome measures (PROMS) compared to two interforaminally placed, earl…
Phase: NA • Sponsor: University of Bern • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New study tracks neck surgery success with spacers
Knowledge-focused Recruiting nowThis is a prospective study to assess fusion rates and cervical sagittal parameters following posterior cervical arthrodesis procedures supplemented with CIS. Data will be collected from medical records for up to 730 days after surgery. Data to be collected will be demographic, p…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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One surgery instead of two for kids' hearing implants?
Symptom relief TerminatedOver the last few decades, the classical two-stage surgical procedure for inserting bone-anchored hearing implants (BAHIs) has been modified in adults into a single-stage procedure. This approach has several advantages since it avoids a second surgical procedure. The single-stage…
Sponsor: Radboud University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Lung and sleep disorder study seeks clues for better diagnosis
Knowledge-focused Recruiting nowClinically, all patients with interstitial lung disease(ILD) were observed, and relevant clinical data were collected. Bronchoscopic specimens were collected according to the condition of the enrolled patients, and the rapid on site evaluation(ROSE) was evaluated, combined with t…
Sponsor: Dan Liu • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Brain training for first responders: can a 5-Session class boost PTSD resilience?
Knowledge-focused CompletedA substantial proportion of public safety personnel (PSP) develop service-related posttraumatic stress disorder (PTSD). PTSD is associated with a range of negative outcomes and its exact underlying neurophysiological mechanism is still not well understood. Cognitive behavioral th…
Phase: NA • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Scientists map nerve signals to improve gastric stimulation for stomach paralysis
Knowledge-focused OngoingThis study aims to characterize how vagus nerve compound action potentials (CNAPs) conduct along the vagus nerve in gastroparetic patients receiving GES therapy using a flexible, non-invasive multielectrode array (MEA).
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Study probes how kids, parents, and doctors recall the moment of cancer diagnosis
Knowledge-focused OngoingPresent project aims to investigate memories related to a cancer communication diagnosis in pediatric oncology. It evaluates possible common elements and specificity between family and healthcare staff.
Sponsor: Meyer Children's Hospital IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC