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127005 trials found · Page 4994 of 6351
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Dopamine may help you tell fact from fantasy, new study suggests
Knowledge-focused Recruiting nowReality-monitoring characterizes the ability to determine whether information was perceived in the environment or only imagined . Impaired reality-monitoring abilities have been associated with hallucinations in patients with schizophrenia and patients with Parkinson's disease. …
Sponsor: Hôpital le Vinatier • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Can training pot shop staff prevent drunk driving? oregon study aims to find out.
Prevention By invitation onlyThe new recreational marijuana markets are contributing to polysubstance-impaired driving and other harms, especially when marijuana is used in combination with alcohol, by selling marijuana to obviously-intoxicated customers. In this study, the effectiveness of an intervention t…
Sponsor: Klein Buendel, Inc. • Aim: Prevention
Last updated Jun 27, 2026 08:02 UTC
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Fruit and veggie delivery could change kidney diet rules
Disease control Recruiting nowThe study will look at the impact of the potassium content in fruits and vegetables, on serum potassium concentrations in people with Chronic Kidney Disease (CKD) using a randomized crossover design. Participants will receive home delivery of fruit and vegetables with either high…
Sponsor: University of Manitoba • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Eye ultrasound may help monitor brain pressure during keyhole hysterectomy
Knowledge-focused OngoingLaparoscopic total hysterectomy is the most common gynaecological surgical procedure after caesarean section. In laparoscopic total hysterectomy, intraabdominal pressure increases, venous return decreases, hypercarbia and acidosis may occur due to pneumoperitoneum due to CO2 insu…
Sponsor: Balikesir University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Smartphones to unlock daily triggers of restless legs syndrome
Knowledge-focused Recruiting nowThe Restless Legs Syndrome (RLS) is a sensorimotor disorder better characterized by an urge to move the legs at rest. Although treatments are available, many patients experience periods of symptoms relief and exacerbation. Whether this is due to the natural history of the disease…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Antifungal cream could be new acne treatment
Disease control Ongoingobjective: is to assess the efficacy of topical ketoconazole 2% cream in comparison with topical retinoid in the treatment of mild comedonal and papulopustular acne to determine if ketoconazole can be an alternative to topical retinoid with less side effects and more compliance. …
Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New inhaler for COPD shows promise in early trial
Disease control Stopped earlyThis is a randomized, double blind, double dummy, active-controlled, parallel-group study to assess the efficacy and Safety of HRG2005 inhalation in patients with moderate to severe chronic obstructive pulmonary disease. Approximately 200 patients with moderate to severe COPD wil…
Phase 2 • Sponsor: Jiangsu HengRui Medicine Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New fixation method speeds up kidney stone removal
Symptom relief CompletedProspective study to assist safty and efficieny of our technique of using peumatic lithotripsy with suction mini-pcnl.
Sponsor: Yasser Gamil Elnagar • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Antibiotic penetration in pancreatic collections under study
Knowledge-focused OngoingThis observational study aims to evaluate the penetration of intravenously administered antibiotics into pancreatic fluid collections in patients with suspected infected walled-off pancreatic necrosis (WOPN). In selected patients undergoing percutaneous or endoscopic drainage of …
Sponsor: Brno University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Nasal splint may improve tear duct surgery success
Disease control CompletedThis study aims to compare the outcomes of endoscopic DCR performed with versus without internal nasal splints, by assessing functional outcomes, complication rates, and overall success rates.
Sponsor: Kafrelsheikh University • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Can acupuncture boost dry eye relief? new study tests combo therapy
Symptom relief CompletedThis randomized clinical trial was designed to evaluate the effectiveness of acupuncture combined with artificial tears compared to artificial tears alone in patients with moderate dry eye disease. A total of 90 participants were enrolled at the University of Health Sciences, Ank…
Sponsor: Nadide Koca • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Liquid biopsy study halted: did it help guide cancer care?
Knowledge-focused Stopped earlyCirculating tumor DNA assays are becoming relevant for routine diagnostics, but many related aspects are yet unresolved. With this project, the investigators aim to develop pragmatic molecular diagnostic pathways of liquid biopsies relevant in advanced gastrointestinal malignanci…
Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New lung therapy for ICU pneumonia patients under study
Knowledge-focused Recruiting nowThis study aims to explore the application of Electrical Impedance Tomography (EIT) in evaluating the effectiveness of OLE (Oscillatory Lung Expansion) airway clearance therapy for ICU patients with pulmonary infections. The goal is to understand the treatment response difference…
Sponsor: Chinese PLA General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Can cuffs and compression beat Post-Workout pain?
Symptom relief Recruiting nowBoth BFR and intermittent pneumatic compression are purported to decrease symptoms associated with exercise induced muscle damage (EIMD) that cause delayed onset muscle soreness (DOMS). Blood flow restriction relies on applying pressurized cuffs to the most proximal portion of th…
Sponsor: University of Southern California • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Texts and films aim to boost blood donations in ghana
Knowledge-focused CompletedA randomized controlled trial to evaluate the effectiveness of the WhatsApp groups or docudrama compared to a control group (usual engagement with blood services) on repeat blood donation attempts among first-time blood donors in Ghana. Secondary outcomes will be blood donor rete…
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Breathing test could help doctors personalize antibody therapy for immune deficiency
Disease control Recruiting nowAlthough there is evidence in the literature that gammaglobulin replacement therapy can lead to a reduction in the prevalence of pulmonary infection and improved lung function, there is no published study to guide immunologists regarding the use of spirometry in titrating IG ther…
Phase 4 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Bodyweight workouts in school boost teen fitness
Knowledge-focused CompletedThis study evaluates the effectiveness of a school-based calisthenics intervention in promoting physical activity and improving health-related outcomes in adolescents. Physical inactivity during adolescence is a growing public health concern associated with increased risks of obe…
Sponsor: Universitat de Lleida • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Does extra numbing improve hernia surgery recovery?
Symptom relief CompletedThe goal of this clinical trial is to compare the effects of single-level and bi-level erector spinae plane block in open inguinal hernia repair surgery. The main question it aims to answer are: * Whether bi-level ESP block will improve pain control after open inguinal hernia re…
Sponsor: Hospital Authority, Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Mind over MRI: could rewording scan reports ease back pain?
Knowledge-focused CompletedTerminology in radiology reports may cause patients harm by anchoring to or justifying a particular diagnosis. This phenomenon is known as the nocebo effect. MRI may cause patients to pursue more invasive procedures with little added benefit. This study aims to reproduce a study …
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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Caffeine's secret power: boosting workouts for seniors?
Knowledge-focused OngoingIntroduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance. However, little is known about the prolonged effects of this supplement on neuromuscular adaptations to …
Sponsor: Alberto Pérez-López • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC