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127005 trials found · Page 4983 of 6351
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Breast cancer drug may throw patients off balance, study finds
Knowledge-focused CompletedTo evaluate the effects of aromatase inhibitors on lower extremity ultrasonographic measurements, static and dynamic balance scores in breast cancer patients using aromatase inhibitors
Sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:35 UTC
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Small study checks kidney and race impact on transplant drug
Knowledge-focused CompletedThis study aim is to assess, if treosulfan pharmacokinetics are influenced by declined renal function and by race/ethnicity of patients. The study also aims to determine an appropriate safe dose of treosulfan, when patient's renal function is impaired. The participants of this st…
Phase 1 • Sponsor: medac GmbH • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Back block breakthrough: less painkiller needed during spine surgery?
Symptom relief CompletedIn recent years, regional anesthesia techniques have also been frequently applied to patients for pain relief. Erector spinae plane block (ESPB), is among the regional anesthesia techniques frequently used in lumbar spine surgery. General anesthesia (GA) is the main method of an…
Sponsor: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Racial divide in smoking and stress: new study seeks answers
Knowledge-focused CompletedThe purpose of this study is to examine racial differences in smoking behaviors and stress responses between African American and white male smokers.
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Global study digs into Real-World prostate cancer care
Knowledge-focused Recruiting nowStudy wants to explore real-world data in three distinct settings * Patients with metachronous or de novo mCSPC treated with ADT+ARSI or ADT+ARSI+docetaxel \_ARON-3S * Patients receiving Lutetium-177 PSMA for mCRPC \_ ARON-3Lu * Patients treated with PARP inhibitors (alone or co…
Sponsor: Hospital of Macerata • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Lavender scent calms nerves before needle procedures, study finds
Symptom relief CompletedThe goal of this study is to evaluate the effect of lavender essential oil on pre-procedure anxiety for patients undergoing ultrasound guided musculoskeletal procedures
Sponsor: University of Miami • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Heart MRI may help decide who needs a heart monitor after stroke
Knowledge-focused Recruiting nowAtrial fibrillation is a cardiac arrhythmia most often originating in the left atrium, causing anarchic electrical activity and thus a loss of atrial contraction. This increases the risk of stroke through clot formation in the atrium, but also of heart failure. Atrial fibrillatio…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Brain wave watch: new monitor may cut ICU delirium and ventilator time
Knowledge-focused CompletedThe goal of this multi-site observational study is to compare delirium rates, days on mechanical ventilation, and Post Intensive Care Syndrome (PICS) rates in adult Intensive Care Unit (ICU) patients. The study will examine patients whose sedation and analgesia infusion titration…
Sponsor: Fraser Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Phone-Based results boost cervical cancer screening Follow-Up in el salvador
Knowledge-focused CompletedTelemedicine, the use of telecommunication technologies to provide healthcare services remotely, has grown exponentially in the last decade. The COVID-19 pandemic highlighted the potential of these approaches as routine clinical interactions transitioned from in-person to virtual…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC
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Smart shoes could revolutionize gait analysis for kids with cerebral palsy
Knowledge-focused Recruiting nowCerebral palsy (CP) is currently one of the major causes of disability in children. The presence of various disorders (muscle stiffness, architectural bone defects, spasticity) leads to a number of functional impacts, including severe impairment of mobility, particularly locomoti…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Pharmacists may cut dangerous delays in blood infection alerts
Knowledge-focused CompletedPatients are commonly discharged from the Emergency Department(ED) with pending blood culture results. Blood cultures can take up to 48 hours to become positive which is why it is important to notify patients with true positive cultures as soon as possible. Delay in notification …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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Ice therapy soothes throat pain after sleep apnea surgery, study finds
Symptom relief CompletedThe purpose of this study will to evaluate the degree of postoperative sore throat and Life Impairment changes in patients with sleep apnea who underwent da Vinci robotic arm surgery as an intervention of oral cryotherapy.
Sponsor: Chung Shan Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Massive study reveals hidden toll of ICU on ARDS survivors
Knowledge-focused CompletedThis is an observational study in which data already collected from people with acute respiratory distress syndrome (ARDS) admitted to an intensive care unit (ICU) are studied. ARDS is a life-threatening condition in which fluid builds up in the lungs making breathing difficult.…
Sponsor: Bayer • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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New training aims to make dementia care more inclusive for LGBTQ+ seniors
Knowledge-focused CompletedThis study is designed to help improve the care of sexual and gender minority (SGM) with Alzheimer's Disease and Alzheimer's Disease Related Dementia (AD/ADRD) in long-term services and supports (LTSS) by training the state's LTSS workforce in SGM culturally responsive care. The …
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Heart surgery fluid strategy under scrutiny for kidney safety
Knowledge-focused Recruiting nowAcute normovolemic hemodilution (ANH) is performed as a blood conservation technique during surgical procedures with high risk for significant blood loss. It is done by taking out some of the patients blood before surgery actually begins and storing this blood inside of the opera…
Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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300 patients tracked to uncover hidden cancer risks in common mouth condition
Knowledge-focused Recruiting nowThe main objective of this paper will be to evaluate the rate of malignant transformation among a cohort of patients affected by oral lichen planus with long-term follow-up. Secondary aims will be to study and describe the characteristics of these patients to identify potential r…
Sponsor: Catholic University of the Sacred Heart • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New app aims to ease stress for parents of preterm infants
Symptom relief Recruiting nowThe app-based diagnostic and support approach with a focus on mental and somatic symptoms is intended to strengthen the resilience of premature born children and families and to identify risk and resilience factors.The overall objective of the study is to improve the post-inpatie…
Sponsor: University Hospital Tuebingen • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Could ditching Beta-Blockers boost heart Patients' exercise?
Symptom relief CompletedThe study team will generate preliminary data on whether patients with cardiac amyloidosis feel better when their beta-blocker is stopped. To achieve this objective, 20 N-of-1 trials (on vs. off) will be conducted, and the study team will subsequently interview participants to be…
Phase 4 • Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated Jul 31, 2026 00:00 UTC
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Paving the way: new study aims to sharpen tools for LGMD R1 trials
Knowledge-focused OngoingThis is a 24-month, observational study of 100 participants with Limb Girdle Muscular Dystrophy type R1, also known as CAPN3.
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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New questionnaire aims to track throat discomfort after thyroid surgery
Knowledge-focused Recruiting nowThe goal of this observational study is to develop a questionnaire for measuring swallowing and throat discomfort symptoms in patients with goiter or thyroidectomy, which complies with the model of Rasch and which satisfies the fundamental measurement axioms (e.g., unidimensional…
Sponsor: Istituto Auxologico Italiano • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC