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127005 trials found · Page 4957 of 6351
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Hidden seizures after stroke: EEG may spot them early
Knowledge-focused Recruiting nowΤhe aim of the study is to investigate the role of EEG both in predicting epileptogenesis in patients with acute stroke and in detecting and clarifying the clinical significance of subclinical epileptic seizures in a stroke unit. More specifically, the performance of routine EEG …
Sponsor: Attikon Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Sound wave test may simplify COPD monitoring
Knowledge-focused CompletedThis study aimed to evaluate small airway function during ECOPD and recovery periods using IOS. In this prospective single-center study, patients with ECOPD underwent evaluation of their pulmonary functions using IOS and spirometry during exacerbation and recovery (6-12 weeks aft…
Sponsor: Deniz Bilici • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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New imaging software could sharpen brain surgery planning
Knowledge-focused CompletedThe objective of this project is to evaluate next generation visualization tools and surgical targeting models for clinical deep brain stimulation (DBS). This study will evaluate the performance of HoloDBS software in comparison to the current standard (SOC) clinical planning to…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
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Social circles as medicine: tanzania study tests peer support for opioid recovery
Knowledge-focused CompletedInvestigators will adapt the Brief Social Behaviour and Network Therapy (B-SBNT) intervention developed to facilitate recovery among people receiving medication-assisted treatment for opioid use disorder in the United Kingdom. The B-SBNT involves families and the wider social net…
Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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AI set to revolutionize MS diagnosis and monitoring
Knowledge-focused Recruiting nowThe RECLAIM study aims to gather a centralized and harmonized dataset, enabling the secondary use of data for building AI-based models that will support diagnosis and prognosis of individual Multiple Sclerosis patient's disease course and treatment response in a real-world settin…
Sponsor: icometrix • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New decision tree aims to improve hip fracture surgery outcomes
Knowledge-focused CompletedAcetabular fractures are challenging fractures to treat. Many fracture patterns occur, in a deep anatomical area surrounded by numerous vascular and nervous elements, generally in a polytraumatic context . A reduction with less than 2 mm of incongruence is generally considered ac…
Sponsor: University Hospital, Grenoble • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Could an antidepressant ease Post-Mastectomy pain?
Symptom relief CompletedOur aim in this study will be to investigate the effect of mirtazapine on acute post-mastectomy pain manifested by total morphine consumption in first 24 hours and VAS score at rest and movement (primary outcomes). chronic neuropathic pain using LANSS Pain Scale (Leeds Assessment…
Early phase 1 • Sponsor: Assiut University • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Oxygen dressing shows promise for healing diabetic foot wounds
Symptom relief CompletedThis study is a prospective randomized controlled pilot study evaluating the efficacy and safety of an OEOd-based wound dressing compared with standard wound care in patients with post-surgical diabetic foot ulcers. Participants were randomly assigned at enrollment to receive eit…
Sponsor: Ospedale San Donato • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Couples study links booze and trauma to domestic violence
Knowledge-focused Recruiting nowIntimate partner violence (IPV) is a serious public health problem that results in significant health and economic burdens including mortality, morbidity, and poor treatment outcomes. A well-developed field of research suggests that alcohol misuse and posttraumatic stress disorde…
Sponsor: Medical University of South Carolina • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Study examines best sequence of treatments for advanced bowel cancer
Knowledge-focused CompletedThis is an observational study in which data already collected from people with metastatic colorectal cancer will be studied. Metastatic colorectal cancer (mCRC) is a cancer of the colon (large bowel) or the rectum (lowest part of the bowel just before the anus). Cancer is consi…
Sponsor: Bayer • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Can a simple training program ease back and neck pain for healthcare workers?
Disease control Recruiting nowThis study evaluates an ergonomics intervention to reduce work-related musculoskeletal disorders (MSDs) among dental healthcare workers in Dubai government hospitals, where up to 90% prevalence affects the lower back, neck, shoulders, and upper extremities due to repetitive tasks…
Sponsor: Universiti Putra Malaysia • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Can we predict who will benefit from tic therapy? new study aims to find out
Knowledge-focused Recruiting nowChronic tics are a disabling neuropsychiatric symptom associated with multiple child-onset mental disorders. Chronic tics affect 1-3% of youth and can be associated with impaired functioning, emotional and behavioral problems, physical pain, diminished quality of life, and peer v…
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Saliva test could predict reflux after esophageal cancer surgery
Knowledge-focused By invitation onlyThe goal of this observational study intends to explore the evolution trend and related factors of postoperative reflux of esophageal cancer based on PEPTEST detection, in order to identify postoperative reflux The main question it aims to answer are: to provide evidence for hi…
Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Could boxing in VR help MS patients get fit?
Symptom relief CompletedTITLE: Immersive Virtual Reality and Exercise Programs in Multiple Sclerosis INTRODUCTION: Multiple sclerosis (MS) is a chronic neuroimmunological and degenerative disease characterized by demyelination within the central nervous system. Its clinical course involves motor impair…
Sponsor: University of Vigo • Aim: Symptom relief
Last updated Jul 26, 2026 00:00 UTC
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Bile acid pill may shrink gallbladder polyps, study hopes
Disease control OngoingThe goal of this observational study is to learn about the impact of ursodeoxycholic acid treatment on the gallbladder polyp evolution in patients with gallbladder polyps that undergo follow up. The main question it aims to answer is: • Whether ursodeoxycholic acid could decreas…
Sponsor: Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New digital breathing coach aims to ease breathlessness
Symptom relief Recruiting nowThe primary aim will be to understand whether a digital breathing biofeedback system can improve the outcomes of physiotherapist guided breathing retraining.
Sponsor: University of Salford • Aim: Symptom relief
Last updated Aug 21, 2026 00:00 UTC
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Ultrasound could help doctors manage fluids during kidney treatment
Knowledge-focused CompletedHemodynamic management of critically ill patients has long been focused on the arterial side of the vasculature by assessing adequate perfusion pressure. However, the venous pressure is also of critical importance. Venous congestion can occur in patients with right ventricular fa…
Sponsor: Chulalongkorn University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Diet and exercise combo may boost bone health in seniors
Disease control CompletedThis randomized controlled trial was designed to investigate the effects of progressive resistance training (PRT) combined with a Mediterranean diet on bone mineral density (BMD) and bone turnover markers (BTMs) in older adults. Participants underwent a detailed medical history …
Sponsor: University of Sfax • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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ER study aims to keep Low-Risk clot patients out of hospital
Knowledge-focused CompletedThis study is a quality improvement project to evaluate health care management of pulmonary embolism (PE) patients. The researchers are testing an intervention to determine if it prevents unnecessary hospital admissions.
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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16-minute workout boosts brainpower in students, study finds
Knowledge-focused CompletedPrevious studies in young adults have shown that physical activity can generate positive emotions and improve attention, among other cognitive functions. This highlights the importance of evaluating how physical activity can affect cognition and affective dimensions. However, to …
Sponsor: Universitat Jaume I • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC