Saliva test could predict reflux after esophageal cancer surgery

NCT ID NCT06509022

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study follows 138 people who had surgery for esophageal cancer. Researchers use a saliva test called PEPTEST to measure reflux before and after surgery. The goal is to understand how often reflux happens and what factors, like surgical technique or lifestyle, might affect it. This is not a treatment study, but it could help improve future care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help identify patients at high risk for reflux after esophageal cancer surgery, leading to better prevention and management strategies.
What could go wrong: This is an observational study, not a treatment trial. It will not directly improve outcomes for participants, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

digestive system neoplasm esophageal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTROINTESTINAL NEOPLASMS

Contacts and locations

Locations

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Beijing, China

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