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127005 trials found · Page 4740 of 6351
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Scientists map cancer spread in low rectal tumors to guide surgeons
Knowledge-focused CompletedThe purpose of this study is to study the law of intramural diffusion of low rectal cancer in different stages, and to explore the relationship between intramural diffusion of low rectal cancer and the distal resection margin during operation, so as to provide theoretical basis f…
Sponsor: First Affiliated Hospital of Wenzhou Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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1,000-Patient study to decode widespread artery disease
Knowledge-focused Recruiting nowThis study aims to establish a standardized cohort for panvascular diseases, encompassing biological materials such as DNA samples, along with extensive patient medical records and follow-up information. The design of this database will enable it to serve as a comprehensive resou…
Sponsor: Jinwei Tian • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:40 UTC
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Could a gentle electric current ease pain after knee surgery?
Symptom relief By invitation onlyThe Effect of TENS on Early Outcomes in Incisional Wounds After Total Knee Replacement Incisional wounds heal within 3 to 4 weeks, consistent with the normal healing process. However, pain is experienced during the wound healing phase, which can negatively impact patients' recov…
Sponsor: Cukurova University • Aim: Symptom relief
Last updated Jun 26, 2026 13:33 UTC
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New feeding protocol aims to help sick kids recover faster in the ICU
Disease control Recruiting nowThe aim of the study to evaluate the effectiveness and patient's outcome after implementing enteral nutrition algorithm designed to achieve optimal enteral nutrition delivery in the pediatric intensive care unit and to evaluate the effect of implementing this protocol on critical…
Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Smoking worsens gum disease by changing immune cell behavior
Knowledge-focused CompletedThis observational case-control study investigates the effect of smoking on macrophage polarization in the pathogenesis of periodontitis. Adult participants who were either systemically healthy smokers or non-smokers, and who met the clinical criteria for periodontal health or pe…
Sponsor: Suleyman Demirel University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Shock therapy for needle jitters: AcuTENS tested in prostate biopsy
Symptom relief OngoingThis study evaluates whether transcutaneous electrical nerve stimulation applied at specific acupuncture points (AcuTENS) can reduce pain and anxiety during transrectal ultrasound-guided prostate biopsy for participants suspected of prostate cancer. Many patients experience signi…
Sponsor: University of Malaya • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Customizing breathing machines during surgery may help lungs recover faster
Knowledge-focused OngoingAtelectasis may be encountered in the patient population aged 18-65 years undergoing elective laparoscopic bariatric surgery under general anesthesia with endotracheal intubation. The aim of this study is to compare oxygenation, postoperative atelectasis, and postoperative respir…
Sponsor: Yeditepe University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Breathless after COVID? your diaphragm might be the culprit
Knowledge-focused CompletedFatigue and exercise intolerance after survived COVID-19-infection might be related to weakness of the respiratory muscles. The aim of the project is to measure respiratory muscle function and strength in our respiratory physiology laboratory in patients who were not hospitalized…
Sponsor: RWTH Aachen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Scientists peek inside brain during Parkinson's surgery to unlock movement secrets
Knowledge-focused Recruiting nowWhen a patient gets DBS surgery, the neurosurgeon makes a hole in the skull through which they can put the DBS lead down in deep parts of the brain that help control movement. For this study, research participants will also have an ECoG strip put through the same hole (no extra h…
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Acupuncture may help bladder function after cervical cancer surgery
Symptom relief CompletedThis is a retrospective cohort study using a paired control design. We will review the patients of PUR after cervical cancer surgery who went to the acupuncture department and the urinary retention department in Zhejiang Cancer Hospital from October 2020 to August 2024, and 73 pa…
Sponsor: Lu Chao • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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New pain block tested for kids' surgery: could it replace the standard?
Symptom relief CompletedThis study aims to evaluate the safety and efficacy of ultrasound-guided sacral multifidus plane block and compare its analgesic effect to ultrasound-guided caudal block in pediatric patients undergoing hypospadias surgery under general anesthesia
Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Phone calls may boost bipolar treatment success
Disease control CompletedThis research is a randomized controlled experimental study with a pretest-posttest design, conducted to determine the effect of telenursing counseling on functionality and treatment adherence levels in patients with bipolar disorder. First, patients followed up with a diagnosis…
Sponsor: Didem Ayhan • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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AI assistant tested to boost happiness in clinic visits
Knowledge-focused Recruiting nowThis multicenter cluster-randomized study evaluates the impact of an artificial intelligence (AI) tool on the satisfaction of healthcare professionals and patients in outpatient consultations, measuring its effect on perceived satisfaction (through a visual analog scale), the dur…
Sponsor: Universidad Autonoma de Madrid • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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AI could speed up complex reconstructive surgery planning
Knowledge-focused Recruiting nowComputer-assisted surgery has revolutionized reconstruction with more efficient, accurate, and predictable surgery, as reported in our previous studies. Skin perforators are vessels that travel through muscles and septa to supply the skin. The identification of skin perforators i…
Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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New clot test could speed up care for postpartum bleeding
Knowledge-focused CompletedPostpartum hemorrhage is the leading cause of maternal morbidity and mortality throughout the world. Rapid diagnosis and early management improve maternal prognosis. Postpartum hemorrhage is defined by a blood loss exceeding 500 ml during the 24 h after delivery. There are many…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Can a daily pill and night serum fade dark spots? new trial aims to find out
Symptom relief CompletedThe goal of this study is to evaluate the safety and efficacy of a combination use of oral supplement and topical serum in improving skin pigmentation in healthy women. The main questions it aims to answer are: Does combination use able to reduce the dark spot? Is there any adve…
Sponsor: USMARI Research & Innovation Centre • Aim: Symptom relief
Last updated Aug 02, 2026 00:00 UTC
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New scale aims to understand how vestibular migraine patients think about their condition
Knowledge-focused CompletedVestibular migraine (VM) is a neurological condition characterized by recurrent episodes of dizziness, imbalance, and migraine-related symptoms. Individuals' responses to health problems are influenced by their health beliefs. The Health Belief Model (HBM) is widely used to evalu…
Sponsor: Istanbul Aydın University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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New remote therapy shows promise for kids with cerebral palsy
Symptom relief CompletedThe perpose of this study: Development and demonstration of a teletherapy protocol to improve upper limb function in children with cerebral palsy.
Sponsor: Samsung Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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New study tests best stitch pattern for mastectomy scars
Symptom relief CompletedInvestigators aimed to assess the comparative impact of two different closure techniques on cosmetic outcomes and patient satisfaction; investigators want to analysis operative time, wound healing and postoperative complications in both techniques
Sponsor: University of Faisalabad • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Ozone gas may ease pain after wisdom tooth surgery
Symptom relief CompletedThe goal of this clinical trial is to learn if use of ozone works to treat complications after impacted mandibular third molar surgery. It will also learn does ozone has positive effect on wound healing and quality of life. The main questions it aims to answer are: * Does ozone…
Phase 3 • Sponsor: Jelena Krunic • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC