Ozone gas may ease pain after wisdom tooth surgery
NCT ID NCT06802354
First seen Jun 20, 2026 · Last updated Jun 20, 2026
Summary
This completed Phase 3 trial tested whether applying gaseous ozone to the extraction site after impacted wisdom tooth surgery can reduce common complications like pain, swelling, and difficulty opening the mouth. Twenty adults with similar wisdom tooth impactions received either ozone or a sham treatment for 30 seconds. Researchers measured pain, swelling, and healing over a week, and also tracked quality of life. The goal is to see if ozone can make recovery smoother.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of East Sarajevo, Faculty of Medicine
Foca, Republika Srpska, 73300, Bosnia and Herzegovina
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
gaseous ozone
What this could lead to
If it works, this could offer a simple, low-cost way to reduce pain and swelling after wisdom tooth surgery.
What could go wrong
This is a very small trial with only 20 participants, so results may not apply to everyone. Ozone also has known risks for certain medical conditions.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.