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Your own blood may be the key to easier wisdom tooth recovery

NCT ID NCT07742826

Recruiting now Symptom relief Sponsor: Final International University Source: ClinicalTrials.gov ↗

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This trial tests whether a special blood clot called platelet-rich fibrin (PRF), made from a patient's own blood, can reduce pain, swelling, and jaw stiffness after impacted wisdom tooth surgery. It compares PRF alone, PRF plus a corticosteroid injection, and standard care in 60 adults. Participants are randomly assigned to one of three groups, and their recovery is tracked for a week. The goal is to see if PRF, with or without the steroid, offers better relief than usual treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Platelet-rich fibrin (PRF) prepared from the participant's own blood, with or without a single dose of dexamethasone (corticosteroid), compared to standard care.
What this could lead to
If PRF proves effective, it could offer a natural, low-cost way to ease pain and swelling after wisdom tooth removal, potentially reducing the need for steroids.
What could go wrong
This is a small, early-stage trial (60 people) and results may not apply to everyone. PRF's benefits are uncertain, and adding a corticosteroid carries risks like infection or delayed healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative Postoperative Complications Trismus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IMPACTED LOWER THIRD MOLAR IMPACTED MANDIBULAR THIRD MOLAR EXTRACTION IMPACTED WISDOM TOOTH

Contacts and locations

Locations

  • Final International University Faculty of Dentistry

    RECRUITING

    Nicosia, 2323, Cyprus

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