Tooth-Derived graft may boost jaw bone healing after cyst removal
NCT ID NCT07652216
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using a patient's own tooth-derived bone graft (ADDM) combined with a platelet-rich fibrin (A-PRF) can improve bone healing after removing a dentigerous cyst and an impacted wisdom tooth. Thirty-five adults with this condition will receive either standard care (blood clot), A-PRF alone, or A-PRF plus ADDM. The main goal is to measure bone defect reduction on CT scans at 6 and 12 months, with pain as a secondary outcome.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Autogenous Demineralized Dentin Matrix (ADDM) and Advanced Platelet-Rich Fibrin (A-PRF)
What this could lead to
If successful, this approach could speed up bone regeneration and reduce pain after jaw cyst surgery, offering a better recovery option.
What could go wrong
This is a small, early-stage study with only 35 participants, so results may not apply to everyone. The treatments are experimental and may not improve healing over natural blood clot formation.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Oral Surgery, Institute of Dentistry, Jagiellonian University Medical College
Krakow, Malopolska, 31-155, Poland