Could your own blood speed wisdom tooth recovery?

NCT ID NCT07672951

Completed Symptom relief Sponsor: PAEC General Hospital, Islamabad Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This trial tests whether placing a clot made from a patient's own blood (platelet-rich fibrin, or PRF) into the socket after wisdom tooth removal can reduce pain, jaw stiffness, and facial swelling. About 134 adults with impacted lower wisdom teeth will receive either PRF or a standard gelatin sponge. Researchers will measure pain, mouth opening, and swelling before surgery and again on days 1 and 7 after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Platelet-rich fibrin (PRF)
What this could lead to: If it works, PRF could become a standard, low-cost way to speed recovery and reduce discomfort after wisdom tooth surgery.
What could go wrong: This is a single-center trial with 134 participants, so results may not apply to everyone. PRF may not outperform the standard gelatin sponge, and individual healing varies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Edema Pain, Postoperative Trismus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EDEMA FACE IMPACTED MANDIBULAR THIRD MOLAR POSTOPERATIVE PAIN TRISMUS

Contacts and locations

Locations

PAEC General Hospital, Islamabad

Islamabad, Federal, 44100, Pakistan

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