Could your own blood speed wisdom tooth recovery?

NCT ID NCT07672951

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This trial tests whether placing a clot made from a patient's own blood (platelet-rich fibrin, or PRF) into the socket after wisdom tooth removal can reduce pain, jaw stiffness, and facial swelling. About 134 adults with impacted lower wisdom teeth will receive either PRF or a standard gelatin sponge. Researchers will measure pain, mouth opening, and swelling before surgery and again on days 1 and 7 after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Platelet-rich fibrin (PRF)

What this could lead to

If it works, PRF could become a standard, low-cost way to speed recovery and reduce discomfort after wisdom tooth surgery.

What could go wrong

This is a single-center trial with 134 participants, so results may not apply to everyone. PRF may not outperform the standard gelatin sponge, and individual healing varies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Edema Pain, Postoperative Trismus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • PAEC General Hospital, Islamabad

    Islamabad, Federal, 44100, Pakistan