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127005 trials found · Page 4662 of 6351
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Can a simple phone call keep cirrhosis patients out of the hospital?
Disease control Recruiting nowThe goal of this clinical trial is to learn about an intensive monitoring plan (transitional care program) in patients with cirrhosis and excessive swelling that are going to be discharged from the hospital. The main question\[s\] it aims to answer are: * How much time and what…
Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Can a diabetes drug beat acne? new study says maybe
Symptom relief CompletedThe goal of the clinical trial is to learn if oral metformin works to treat moderate to severe acne vulgaris. Investigators will compare this drug to oral doxycycline to see if this drug works to treat acne. All participants will be divided into two groups. Group A will be give…
Phase 4 • Sponsor: Ghurki Trust and Teaching Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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New shoulder stretch could help bowlers throw faster with less pain
Symptom relief CompletedThe goal of this clinical trial is to determine combined effects of the Kinetic control for shoulder on pain, range, and function among fast bowlers. The main question it aims to answer is: Does mulligan mobilization with movement along with kinetic medial rotation control work …
Sponsor: Lahore University of Biological and Applied Sciences • Aim: Symptom relief
Last updated Aug 12, 2026 00:00 UTC
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Can a hand massage soothe pain and nerves after heart surgery?
Symptom relief CompletedThere is no study finding examining the effects of the classical hand massage and hand reflexology massage methods on pain, anxiety and physiological parameters after coronary angiography. Therefore, the aim of this study is to examine the effects of reflexology hand massage and …
Sponsor: Kutahya Health Sciences University • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Sleep and stress supplement put to the test in new study
Symptom relief CompletedThe purpose of this clinical trial is to assess the effects of a supplement combination on measures of sleep quality and stress in healthy adults.
Sponsor: University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Heart defects may complicate recovery for childhood cancer survivors
Knowledge-focused CompletedThis study aims to determine whether congenital heart disease increases chronic health risks and mortality in childhood hematological tumor survivors, explore potential shared genetic factors between these conditions, identify other factors affecting long-term outcomes and qualit…
Sponsor: Children's Hospital of Fudan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Study reveals how much pain relief actually matters for period cramps
Knowledge-focused CompletedThe aim of this study is to determine the Minimal Clinically Important Difference (MCID) for the Visual Analog Scale (VAS), Menstrual Symptom Questionnaire (MSQ), and Functional and Emotional Measure of Dysmenorrhea (FEMD) in patients with primary dysmenorrhea (PwPD).
Sponsor: Artvin Coruh University • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:00 UTC
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Laser plus drops: a new combo for glaucoma?
Disease control CompletedA randomized, single-site, parallel-group, prospective study of patients who are candidates for SLT, to study the effect of IOP change with Rocklatan vs artificial tears.
Sponsor: Colorado Ophthalmology Associates PC • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Wrist surgery pain breakthrough? lower anesthetic dose may ease rebound pain
Symptom relief CompletedThe goal of this clinical trial is to see if the concentration of a local anesthetic (ropivacaine) in peripheral nerve block is related to the severness of pain after surgery of distal radius fractures in adults. The main questions it aims to answer are: * Is concentration of r…
Phase 4 • Sponsor: Oslo University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:10 UTC
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3D printed retainers tested against traditional wires in new study
Knowledge-focused OngoingAlthough different materials of mandibular fixed retainer were discussed in the literature, there is contradicting evidence regarding the bond failure of Titanium fixed metal retainer, whether immediate or after 12 months. Moreover, insufficient evidence is present regarding 3D m…
Sponsor: Mariam Alaa • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New bioactive fillings could make cavity repairs last longer
Disease control OngoingThis randomized split-mouth clinical trial aims to evaluate the clinical performance of bioactive restorative materials used in Class II restorations in permanent posterior teeth. The study compares a giomer-based bulk-fill restorative material, a giomer restorative material, and…
Sponsor: Hacettepe University • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Smartphone app may predict heart problems without ultrasound
Knowledge-focused Recruiting nowEligible patients will be interviewed by research staff to explain the trial design and rationale. Written informed consent will be obtained from patients who voluntarily agree to participate. Demographics and medical history will be obtained. A 12-lead ECG will be performed; it …
Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Citrus compound meets cannabis: scientists study their combined effects
Knowledge-focused Recruiting nowThe current clinical trial will investigate the effects of orally administered d-limonene (limonene), delta-9-tetrahydrocannabinol (THC) and the combination in healthy adult volunteers.
Phase 1 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Smooth transitions: a study on how disabled youth navigate adult healthcare
Knowledge-focused CompletedTransition to adult care is a purposeful and structured movement of youth with complex disabilities from child centered to adult oriented services. This complex and potentially challenging period requires careful planning. The investigators aim to examine the transition practic…
Sponsor: Centre Hospitalier Universitaire de Saint Etienne • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Can compression wear stop the dizziness? study tests socks, tights, and belts
Knowledge-focused CompletedOrthostatic hypotension (OH) is associated with an increased risk of myocardial infarction, stroke, heart failure and neurocognitive disorders. In the elderly, OH is an independent predictor of falls and mortality. Non-drug treatments are used as the first-line treatments. Among …
Sponsor: Gérond'if • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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New training aims to improve mental health care for new moms
Knowledge-focused Recruiting nowAppropriate training for perinatal mental health care is an important public health concern as mental health disorders are common pregnancy complications. Perinatal and mental health care providers report the difficulty of treating perinatal individuals due to insufficient inform…
Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Scientists dig into past cases of rare lymphoma to find clues for better care
Knowledge-focused Recruiting nowThis is an observational, multicenter, international and retrospective study, that aims to collect data on clinical and pathological characteristics, treatment regimens, outcome, and prognostic factors (clinical, biomarkers and/or radio-metabolic) in patients affected by PBL.
Sponsor: Fondazione Italiana Linfomi - ETS • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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New Alzheimer's drug candidate J4 enters first human safety trials
Knowledge-focused Recruiting nowA Phase I, Randomized, Double-blinded, Placebo-Controlled First-in-human Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of J4 Dry Powder Capsule after Oral Administration of Single and Multiple Ascending Doses to Healthy Adults
Phase 1 • Sponsor: Academia Sinica, Taiwan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Could sepsis prematurely age your immune system?
Knowledge-focused Recruiting nowThe goal of this observational study is to learn about how transposable element levels affect the patient outcomes in sepsis. The main questions it aims to answer is: 1. Do transposable elements prematurely age the immune systems of patients with sepsis? 2. Do transposable eleme…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Parent-Child therapy may ease anxiety and depression, new study suggests
Knowledge-focused Recruiting nowThe goal of this study is to explore possible benefits of Parent-Child Interaction Therapy (PCIT). The main goals of the study are: * To investigate whether pre-survey measures of autonomic reactivity relate to the overall functioning of participants. * To examine the effects of…
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC