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116076 trials found · Page 4658 of 5804
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Why did COVID-19 hit african americans harder? new study digs into the 'Why'
Knowledge-focused CompletedBackground: The COVID-19 pandemic infected and killed African Americans at higher rates than other Americans. Researchers want to understand why. Objective: This natural history study will look at how genetic, environmental, and social factors may predict or affect COVID-19 in…
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Digital coping skills shield kids from divorce stress
Knowledge-focused CompletedThis study will identify components for inclusion in a coping intervention package to reduce mental health problems among children exposed to high interparental conflict after parental separation/divorce. Reappraisal, distraction, and relaxation coping strategies are related to f…
Phase: NA • Sponsor: Arizona State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Tart cherry supplement shows promise for better sleep and less inflammation
Symptom relief CompletedThis study will test the effects of Montmorency cherry supplementation on sleep outcomes and inflammatory biomarkers.
Phase: PHASE1, PHASE2 • Sponsor: Michigan State University • Aim: Symptom relief
Last updated Jun 26, 2026 15:23 UTC
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Can a simple bypass stop reflux after Weight-Loss surgery?
Disease control OngoingThe goal of this clinical trial is to evaluate the effect of GEA on GERD in patients undergoing VSG. The main question it aims to answer is: • Does adoption of GEA to VSG reduce the occurrence of GERD? Participants will complete a symptom questionnaire during follow-up visits. A…
Phase: NA • Sponsor: Clinica Gastrobese • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Steroid boost for headache nerve blocks? new study checks
Symptom relief CompletedCurrently there is limited evidence of benefit for the addition of steroids to occipital nerve blocks for treatment of headache, and not all steroids have been explored. The purpose of this research is to learn more about whether the addition of a specific kind of steroid (dexame…
Phase: PHASE4 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Free genetic tests for families of kids with high cholesterol
Knowledge-focused CompletedIf a child from the Healthy Hearts and Minds education and screening program is found to have a genetic marker for familial hyperlipidemia (FH), immediate family members are offered genetic testing at no charge to identify those at high risk for cardiovascular disorders and those…
Sponsor: Poudre Valley Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Experimental lymphoma combo trial halted early – only 5 patients enrolled
Disease control TerminatedThis study aimed to evaluate the efficacy of a novel regimen consisting of polatuzumab vedotin in combination with rituximab, gemcitabine, dexamethasone, and cisplatin (PV-RGDP) for the treatment of diffuse large B-cell lymphoma that either came back or did not improve after the …
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New program aims to prevent child maltreatment in military families
Prevention CompletedThe purpose of this study is to perform a program evaluation of the Navy and Marine Corps' New Parent Support Program (NPSP) home-visiting option. Both the Navy and Marine Corps have decided to pilot the Take Root Home Visitation (TRHV) curriculum, which is an evidence-informed, …
Phase: NA • Sponsor: Penn State University • Aim: Prevention
Last updated Jun 27, 2026 07:53 UTC
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New diabetes program aims to help arab americans manage blood sugar
Symptom relief Recruiting nowArab Americans (AA) face many challenges in diabetes self-management due to the limited educational resources and support available for them. The cultural and linguistic barriers between patients and health care providers lead to poor diabetes management and outcomes. This study …
Phase: NA • Sponsor: Scripps Whittier Diabetes Institute • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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TikTok Influencers' food ads may sway Kids' snack purchases
Knowledge-focused Recruiting nowRandomized and controlled experimental study to evaluate how influencer food ads on TikTok affect calorie purchases among youth (ages 10-13). Participants will be randomized to one of two conditions: (1) seeing an influencer with food or (2) seeing an influencer without food. Par…
Phase: NA • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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App aims to boost statin adherence in heart patients
Disease control Recruiting nowInterventional study to compare standard of care vs standard of care plus the use of a medication therapy management smartphone app (mediteo m+, Mediteo GmbH, Heidelberg) in patients with atherosclerotic cardiovascular disease and indication to start high intensity statin therapy…
Phase: NA • Sponsor: University Hospital, Essen • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New antibody SHR-1707 tested in early Alzheimer's – safety first
Disease control CompletedThis study aims to evaluate the safety, tolerability and pharmacodynamics of intravenous administration of SHR-1707 In patients with mild cognitive impairment due to Alzheimer's Disease or mild Alzheimer's Disease.
Phase: PHASE1 • Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Enzyme test could open door to new dementia therapy
Knowledge-focused CompletedThis research focuses on the activity of an enzymatic protein: glucocerebrosidase, in dementia with lewy bodies (DLB). Indeed, the mutation of the GBA gene responsible for a decrease in the activity of glucocerebrosidase is the most frequent known genetic risk factor in DLB. Howe…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Screen time may shorten breastfeeding, study suggests
Knowledge-focused Recruiting nowThe benefits of breastfeeding no longer need to be proven. Many studies have shown its positives effects on both infants and mothers. Exclusive breastfeeding is thus recommended within the first six months of life. Excessive screen use has been shown to be harmful in many aspect…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New study tracks IBD patients on biosimilar drug hyrimoz®
Knowledge-focused OngoingAn international, multicenter, non-interventional, prospective, post-authorization, descriptive, non-PASS, study.
Sponsor: Sandoz • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Could a common amino acid soothe stomach pain?
Symptom relief CompletedThe purpose of this research is to collect data from patients diagnosed with functional dyspepsia who are treated with glutamine and describe safety and treatment results compared to patients taking a placebo. Glutamine, an essential amino acid in humans, is an important energy s…
Phase: PHASE1, PHASE2 • Sponsor: David J. Cangemi • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Could a week of steroids help heart failure patients in the ER?
Symptom relief CompletedAcute heart failure (AHF) is a common discharge diagnosis in the emergency department (ED), associated with 1-month mortality of 6%, and a 30% risk rate of 1-month rehospitalisation. Current guidelines recommend the use of nitrates and low dose diuretics to treat congestion, but …
Phase: PHASE2, PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Native american tribe leads study to fight food insecurity and pollution
Knowledge-focused Recruiting nowThe purpose of this study is to build on our equitable, eight-year Tribal-academic partnership with the Ramapough Nation of northern NJ to advance tradition-centered farming practices and management strategies supporting sustainable food systems to relieve local food insecurity a…
Phase: NA • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Mild zaps to the brain may boost arm recovery after stroke
Symptom relief CompletedThis study is a randomized double-blinded trial investigating the effect of Transcranial Direct Current stimulation (tDCS) on upper limb motor function rehabilitation in chronic stroke patients. 51 subjects will be recruited from National University Hospital (NUH) and be randomi…
Phase: NA • Sponsor: National University Hospital, Singapore • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Vegan vs. omnivore: which diet leads to healthier gums?
Knowledge-focused CompletedDiet can influence the body's healing and repair mechanisms. A dietary imbalance obviously cannot trigger periodontal disease in the absence of a primum movens, which is bacterial plaque. However, it can condition its severity and extent by altering the permeability of the oral m…
Phase: NA • Sponsor: G. d'Annunzio University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC