Scientists uncover secrets of gut hormones in Pancreas-Free patients
NCT ID NCT06895408
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed study looked at how two gut hormones, GIP and GLP-1, affect the body in people who have had their pancreas removed. Researchers gave these hormones alone and together to 12 participants to measure changes in blood sugar, fat, and bone markers. The goal was to understand why a new combination drug for diabetes and obesity works better than GLP-1 alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Glucose-dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide 1 (GLP-1)
What this could lead to
If successful, this research could help explain why a new class of combination drugs works better than current GLP-1 treatments for diabetes and obesity.
What could go wrong
This is a small, early-stage study with only 12 participants who have had their pancreas removed, so results may not apply to the general population.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Center for Clinical Metabolic Research, Gentofte Hospital
Hellerup, 2900, Denmark