A blood injection to erase black triangles between teeth?
NCT ID NCT06842277
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This trial tests whether an injectable substance made from a patient's own blood — albumin-platelet rich fibrin — can rebuild the small triangle of gum tissue that is sometimes missing between teeth, creating an unappealing dark gap. The study includes people with mild to moderate gum tissue loss in the front teeth who are otherwise healthy. Researchers will measure how much the black triangle shrinks after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- injectable albumin-platelet rich fibrin (a substance made from the patient's own blood to promote tissue growth)
- What this could lead to
- If effective, this minimally invasive injection could offer a way to fill in unsightly black triangles between teeth without surgery.
- What could go wrong
- This is a very small early-phase trial with only 10 participants, so results may not apply to everyone. The treatment may not produce lasting improvement.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Faculty of Dentistry , Cairo University
Giza, Giza Governorate, 12613, Egypt
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Faculty of Dentistry Cairo University
Giza, Giza Governorate, 12613, Egypt
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