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116076 trials found · Page 4552 of 5804
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One-Shot spine injection could ease hip fracture pain
Symptom relief CompletedThe aim of the study is to investigate postoperative pain relief for patients undergoing surgical treatment of proximal femoral fracture using intrathecal administration of morphine.
Phase: PHASE4 • Sponsor: University Hospital Ostrava • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Brain stimulation study reveals empathy wiring in borderline personality disorder
Knowledge-focused CompletedPeople with borderline personality disorder (BPD) show alterations in the empathic abilities, which may involve the functioning of the mirror neuron system in the somatosensory domain. In the so-called Tactile Mirror System, the observation of a touch on someone else's body activ…
Phase: NA • Sponsor: IRCCS Centro San Giovanni di Dio Fatebenefratelli • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Can tailored therapy help teens with behavioral issues and intellectual disabilities?
Knowledge-focused Recruiting nowThe goal of this observational study is to determine the effectiveness of a specialisation of multisystemic therapy (MST) for adolescents with severe behavioural problems from families with an intellectual disability (ID; MST-ID). To achieve this goal, a mixed method study desig…
Sponsor: De Viersprong • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Can the mediterranean diet survive chemo? new study investigates
Knowledge-focused CompletedThis is an exploratory study aimed at characterizing adherence to the Mediterranean diet among patients undergoing treatment for cancer, in relation to sensory alterations that occur during treatment. The primary strength of this project lies in the consideration of a large numb…
Phase: NA • Sponsor: Centre Antoine Lacassagne • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Sex education boosts intimacy for stoma patients
Symptom relief CompletedIn this study, it was aimed to determine the effect of sexual counseling given to women with stoma with the Ex-PLISSIT model on their sexual life quality and sexual satisfaction. H1: Female patients with permanent stoma who were given sexual counseling with the EX-PLISSIT model …
Phase: NA • Sponsor: NESLİHAN YILMAZ SEZER • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New nutrition pathway aims to spot malnourished kids sooner in hospitals
Knowledge-focused OngoingThe framework for Pediatric Integrated Nutrition Pathway for Acute Care (P-INPAC) was developed by the Canadian Malnutrition Task Force (CMTF); however, it has not been implemented in a research setting. The framework by CMTF for Integrated Nutrition Pathway for Acute Care (INPAC…
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Tiny study hopes to unlock bone healing genes in dental grafts
Knowledge-focused CompletedThe goal of this clinical trial is to compare the expression of multiple genes related to bone regeneration in maxillary bone after being grafted with a commonly used biomaterial supplemented or not with a combination of hyaluronic acid and polynucleotides.
Phase: NA • Sponsor: Universidad de Granada • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Salt sensitivity in kidney disease: a new clue from uromodulin?
Knowledge-focused CompletedIn chronic kidney disease (CKD), hypertension is characterized by the phenomenon of sodium-sensitivity, i.e., the disproportionate increase in blood pressure (BP) due to an increase in dietary sodium consumption to maintain homeostasis through urinary sodium excretion. Impaired r…
Sponsor: Aristotle University Of Thessaloniki • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Brain scans reveal hidden vascular clues in early Alzheimer's
Knowledge-focused OngoingCerebral amyloid angiopathy (CAA), a common cerebrovascular small vessel disease (SVD), is a frequently (98%) found co-morbidity at autopsy in patients with Alzheimer's disease (AD). Current in vivo hallmarks of CAA represent changes relatively late in the disease process and lea…
Sponsor: Leiden University Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:27 UTC
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Massive ICU study aims to slash deadly catheter infections
Disease control Recruiting nowThe goal of this type of study is to construct the continuous quality promotion project "ICU-NO CRBSI(Catheter-Related Bloodstream Infection , CRBSI)" based on improvement science, and to verify its effect in the prevention of central venous catheter-related bloodstream infection…
Phase: NA • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Energy drinks or warming mattress: which keeps C-Section moms warmer?
Symptom relief CompletedIt is not known which is better for intraoperative temperature protection, warming matress or preoperative oral functional drinks in elective cesarean section. We plan to conduct a non inferiority randomized trial to clarify this problem.
Phase: NA • Sponsor: Peking University People's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Could a probiotic pill help kids with PKU?
Disease control CompletedThis is a randomized, double-blind, placebo-controlled, parallel-group study. A total of 15 children with phenylketonuria(PKU) age 3 to 17 years will be randomized to two groups. Experimental group of 10 children will intervene engineered probiotics (CBT102-A) for 20 days and 5 c…
Phase: EARLY_PHASE1 • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Hospital study tracks eye drop risks in 1,000 patients
Knowledge-focused Recruiting nowTo evaluate the association between clinical determinants and the occurrence of adverse drug reactions in hospitalized patients who received tropicamide/phenylephrine 8 mg/50 mg/mL. An ambispective, interventional, longitudinal study will be conducted to actively identify advers…
Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:38 UTC
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New program aims to ease autism transition to adulthood
Knowledge-focused CompletedThe goal of this clinical study is to develop a community-based program to support family members of transition-aged youth on the autism spectrum to help them plan for the future. The main aims of the study are: 1. To develop the Families FORWARD program 2. To conduct proof-of-c…
Phase: NA • Sponsor: Boston University Charles River Campus • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New app aims to catch radiation side effects early
Knowledge-focused Recruiting nowCancer treatment is multidisciplinary and may include radiotherapy. Treatment-related complications represent a burden for patients and the healthcare system. Early recognition of radiotherapy-related side effects is important for timely clinical interventions and improved qualit…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Gentle touch vs. muscle force: which eases back pain best?
Symptom relief CompletedObjective:The study aimed to compare the effectiveness of Positional Release Technique (PRT) and Muscle Energy Technique (MET) in reducing pain and improving outcomes for patients suffering from non-specific low back pain (NSLBP). Materials and Methods: Thirty-six patients betwe…
Phase: NA • Sponsor: Palestine Ahliya University • Aim: Symptom relief
Last updated Jun 26, 2026 16:02 UTC
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New exercise study aims to strengthen back muscles and ease pain
Symptom relief Recruiting nowTo investigate the effect of adding open versus closed chain segmental control exercises to conventional treatment program on pain intensity, lumbar ROM, and CSA of multifidus muscle.
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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1600 people with opioid addiction to be tracked for years to uncover secrets of recovery
Knowledge-focused OngoingThe aim of this study is to describe outcome of people with opioid use disorder over the long-term by collecting monthly and yearly data on their recovery. Adults with opioid use disorder who participate will complete surveys monthly online and once per year by phone about their …
Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Liver biopsy showdown: EUS or needle – patients decide!
Knowledge-focused CompletedPatient Experience in Endohepatology Liver biopsy is a crucial procedure for the diagnosis and/or staging of liver diseases. Common indications for non-targeted biopsies include unexplained elevated liver function tests (LFTs), guiding medical therapy in autoimmune liver diseases…
Sponsor: University Hospital Muenster • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New tool may predict kidney injury after heart surgery
Knowledge-focused CompletedTo predict the renal damage caused by cardiac surgery in patients to try to mitigate it as soon as possible
Sponsor: Universidad de Oviedo • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC