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116076 trials found · Page 4470 of 5804
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New 4D printed cast could make wrist fracture recovery more comfortable
Symptom relief CompletedThis study is a randomised control trial comparing Castomize 4D printed cast versus conventional fibreglass casts in isolated conservatively treated distal radius fractures. The primary outcome measure is fracture reduction. Secondary outcome measures include patient reported out…
Phase: NA • Sponsor: Tan Tock Seng Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Simple ultrasound test may predict dangerous blood pressure drop during brain surgery
Knowledge-focused Recruiting nowThis study aims to assess the accuracy, repeatability, and reproducibility of preoperative evaluation of Inferior Vena Cava (IVC) collapsibility index and caval aorta index for prediction of hypotension after induction of general anesthesia.
Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Simple blood test may predict hidden surgical risks
Knowledge-focused CompletedIn this study, it was aimed to evaluate the presence of intra-abdominal adhesion with biochemical markers before the operation, as well as to determine whether there is a relationship between the severity of adhesion and preoperative blood decorin and TGF β1 levels by examining i…
Sponsor: Celal Bayar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Caffeine's secret power: boosting workouts for seniors?
Knowledge-focused OngoingIntroduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance. However, little is known about the prolonged effects of this supplement on neuromuscular adaptations to …
Phase: NA • Sponsor: Alberto Pérez-López • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Mind over MRI: could rewording scan reports ease back pain?
Knowledge-focused CompletedTerminology in radiology reports may cause patients harm by anchoring to or justifying a particular diagnosis. This phenomenon is known as the nocebo effect. MRI may cause patients to pursue more invasive procedures with little added benefit. This study aims to reproduce a study …
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Video lessons boost caregiver skills in pressure injury prevention
Knowledge-focused CompletedIt is known that caregivers of patients at high risk of developing pressure injury (PBI) have important responsibilities and education to be given to caregivers is necessary for the prevention of PBI. This study was planned to determine the effect of video-assisted training to be…
Phase: NA • Sponsor: Gazi Baran CAMCI • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New study compares implant connectors for better jawbone health
Knowledge-focused Completedthis research aims to compare between using multiunit abutments and OT Equator abutments for constructing implant supported fixed mandibular prosthesis regarding the marginal bone height alteration around the implants through radiographic evaluation
Phase: NA • Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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App + coach: a new way to tackle everyday stress?
Symptom relief CompletedThe goal of this clinical trial is to learn if a coach-guided, app-based mental health program can improve well-being and reduce psychological distress in adults experiencing elevated stress levels. The main questions it aims to answer are: * Does the beWell Tirol program show h…
Phase: NA • Sponsor: Medical University Innsbruck • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Blood-Derived injection may shield teeth from braces damage
Disease control CompletedMandibular incisor crowding is a frequent issue that prompts many adults to seek orthodontic treatment. The treatment may enhance patients' quality of life, facilitate dental plaque control, and improve the quality of periodontal tissue. However, this treatment is accompanied by …
Phase: NA • Sponsor: Damascus University • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Brain games reveal how kids with autism learn language
Knowledge-focused CompletedThe goal of this observational study is to test a reciprocal relationship between statistical learning and the development of language and literacy in first-graders with autism and their non-autistic peers. The main questions it aims to answer are: 1. whether children's statisti…
Phase: NA • Sponsor: Northeastern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Can brain training help depressed young adults stop ruminating?
Knowledge-focused TerminatedIn this project, the investigators use real-time fMRI neurofeedback (rtfMRI-nf) to causally relate dysfunction of right anterior insula (rAI) and right superior temporal sulcus (rSTS) connectivity with the intensity of repetitive negative thinking (RNT). The investigators hypothe…
Phase: NA • Sponsor: Laureate Institute for Brain Research, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Sleep apnea patients stop CPAP for 2 weeks – Here's what scientists learned
Knowledge-focused TerminatedThe goal of this clinical trial is to assess the effect of CPAP withdrawal on vascular and autonomic function in patients with obstructive sleep apnea. The main question it aims to answer is: • Is the pulse wave amplitude index able to predict the impact of sleep apnea treatment…
Phase: NA • Sponsor: Raphael Heinzer • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New support tool aims to ease bladder cancer care burden
Symptom relief Recruiting nowThis clinical trial evaluates the impact of an education and navigation support tool (ENST) on patient and caregiver participation in care coordination for bladder cancer that has spread to nearby tissue or lymph nodes (locally advanced), to other places in the body (metastatic) …
Phase: NA • Sponsor: Roswell Park Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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New keyhole surgery aims to fix stoma hernias with fewer comebacks
Disease control Recruiting nowAbstract: Parastomal hernia is a frequent complication following stoma formation, presenting a significant surgical challenge with high recurrence rates. The present study explores the efficacy of the laparoscopic total extraperitoneal (TEP) approach in parastomal hernia repair,…
Phase: NA • Sponsor: State Budget Public Health Institution Scientific Research Institute - Ochapovsky Regional Clinical Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New patch zaps bladder and bowel troubles away
Symptom relief Recruiting nowUCon is a medical device for treatment of the symptoms of overactive bladder (OAB) and bowel dysfunction (BD). It electrically stimulates the DGN through the skin to obtain modulated behaviour of the bladder/bowel musculature e.g., suppress undesired bladder/bowel activity to rel…
Phase: NA • Sponsor: InnoCon Medical • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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New drug combo for tough prostate cancer shows early promise, but trial halted
Disease control TerminatedThe main purpose of this study is to learn more about the safety and tolerability of abemaciclib when given in combination with darolutamide to participants with prostate cancer that has spread after initial treatment. Participation may last up to 32 months.
Phase: PHASE1 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Gentle back therapy may improve walking in nerve pain patients
Symptom relief CompletedEffect Of Maitland Mobilization On Selected Gait Kinetic And Kinematic Parameters In Patients With Lumbosacral Radiculopathy
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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New lung fibrosis drug SV001 enters first human safety trial
Disease control Recruiting nowThe purpose of this study is to evaluate safety, tolerability, PK and immunogenicity of SV001 compare to placebo in Chinese healthy adult volunteers.
Phase: EARLY_PHASE1 • Sponsor: Shanghai Synvida Biotechnology Co.,Ltd. • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Sugar water shot may ease sciatica pain in ER
Symptom relief CompletedThe goal of this observational study is to see whether it would be feasible to treat patients who come to the emergency department with pain related to sciatica using an ultrasound guided injection of dextrose in water solution ("sugar water") into the tissue that surrounds the s…
Phase: NA • Sponsor: Kaiser Permanente • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Tailored breathing support may reduce lung injury in respiratory failure
Knowledge-focused CompletedThe optimal noninvasive respiratory support for acute hypoxemic respiratory failure is debated. Recent preliminary data indicate that both pressure-support noninvasive ventilation (NIV) and continuous-positive airway pressure (CPAP) may be of benefit. While often applied intercha…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC