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127005 trials found · Page 4462 of 6351
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3D-Printed jaw expanders could make treatment easier for kids
Disease control OngoingThe goal of this clinical trial is to determine whether two types of rapid maxillary expansion (RME) appliances produce different outcomes in children. RME is a treatment utilized to expand a narrow upper jaw. This study will include children aged 8 to 10 years who need upper jaw…
Sponsor: Baskent University • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Spinal zaps help scientists map nerve damage in kids with spina bifida
Knowledge-focused Recruiting nowA study to use transcutaneous spinal cord stimulation to characterize sensorimotor deficits in a pediatric population of individuals with spina bifida.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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New stent aims to keep heart arteries open longer
Disease control PausedThis is a prospective, multi-center, single-arm, open-label, early feasibility study to provide preliminary evidence for the safety and efficacy of the novel IoNIR stent system
Sponsor: Medinol Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Sound waves to the brain: a new hope for addiction?
Knowledge-focused OngoingThe primary objective of this study is to assess the safety and feasibility of FUS neuromodulation in participants with OUD and/or other SUDs.
Sponsor: Manish Ranjan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Text message reminders boost cancer screening in younger adults
Knowledge-focused CompletedThe goal of this study is to learn if sending text message invitations increases participation in colorectal cancer screening among 45-49 year olds in Yingge District, New Taipei City. It will also assess the effectiveness of this method. The main questions it aims to answer are:…
Sponsor: Chang Gung University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Zapping the brain to unlock secrets of aging
Knowledge-focused Recruiting nowThis study investigates how a non-invasive form of brain stimulation, called transcranial direct current stimulation (tDCS), affects brain activity and information processing in younger and older adults. The stimulation uses a very weak electrical current applied through electrod…
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:41 UTC
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Could magnets ease back pain for dialysis patients?
Symptom relief Recruiting nowTo determine the effectiveness of magnetic stimulation application on alleviating back pain and maintaining muscle mass in patients with end-stage renal disease.
Sponsor: Bundang CHA Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 18:58 UTC
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New shot could replace opioids for knee pain in ER
Symptom relief Recruiting nowPatient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.
Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Can breathing exercises help control diabetes? new study investigates
Symptom relief Recruiting nowDiabetes type II is a metabolic syndrome involving high sugar levels known as hyperglycemia. It can impair pulmonary function through reduced lung elasticity and gas exchange and weaken core muscles due to inflammation and muscle atrophy. Literature has shown the individual effec…
Sponsor: Foundation University Islamabad • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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New website aims to help thyroid cancer patients make tough treatment choices
Knowledge-focused Recruiting nowThe goal of this study is to learn if a decision aid (DA) website helps people with thyroid cancer make informed decisions about radioactive iodine (RAI) treatment. The main questions it aims to answer are: - Does the decision aid help participants understand the risks and benefi…
Sponsor: Georgetown University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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New app aims to help Parkinson's patients tackle hidden symptoms
Symptom relief Recruiting nowParkinson's can cause a wide range of non-motor symptoms (NMS), including pain and problems with mental health, memory and sleep. These affect the quality of life of people with Parkinson's (PwP) and their care partners (CP). If these issues are not recognised and managed quickly…
Sponsor: Newcastle University • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Breast expander safety under review in new study
Disease control Recruiting nowThe study investigates the safety and performance of Silimed® brand breast tissue expander in women born with indication for breast reconstruction. The safety of the breast tissue expander will be evaluated by estimating known and unexpected adverse event rates through patient re…
Sponsor: Silimed Industria de Implantes Ltda • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New stroke drug candidate passes first safety check in healthy people
Knowledge-focused CompletedThis study adopted a single-center, randomized, double-blind, placebo-controlled, dose-escalation design and was divided into three parts: single-dose dose-escalation (SAD) 、 multiple-dose dose-escalation (MAD)、drug-drug interaction(DDI)
Phase 1 • Sponsor: Beijing Suncadia Pharmaceuticals Co., Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Virtual physiotherapy tested for arthritis pain relief
Symptom relief PausedDigital health utilization in the form of telerehabilitation is a popular technology that is very little researched for musculoskeletal disorders particularly hip and knee osteoarthritis (OA). The progression of OA will lead to total hip or knee replacement surgery. As a conseque…
Sponsor: Taipei Medical University Shuang Ho Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Shock waves vs lasers: which eases Burn-Related nerve pain better?
Symptom relief CompletedPost-burn cubital tunnel syndrome is a disabling complication that may occur after upper-limb burns involving the elbow due to edema, scar formation, and tissue compression around the ulnar nerve. This randomized controlled trial compared the additive effects of high-intensity la…
Sponsor: Ahram Canadian University • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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New IV drug for high blood pressure enters early human testing
Disease control Recruiting nowThe primary objective of this study is to compare the change from baseline in systolic blood pressure between KN060 and placebo in patients with essential hypertension over 12 weeks; the secondary objectives are to assess the safety and tolerability of KN060 and to assess the pha…
Phase 1 • Sponsor: Suzhou Alphamab Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Apple cider vinegar: the next blood sugar hack?
Symptom relief CompletedThe goal of this clinical study is to investigate the efficacy of a Bragg Apple Cider Vinegar (ACV) liquid on postprandial glucose (PPG) excursion compared to a placebo following a standardized acute carbohydrate load. The main question it aims to answer is: Is there a differenc…
Sponsor: Bragg Live Food Products • Aim: Symptom relief
Last updated Jul 10, 2026 00:00 UTC
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Two cheap blood markers may spot lupus activity early
Diagnosis Recruiting nowThis study aims to evaluate the clinical utility of combining the albumin to globulin ratio (AGR) and the prognostic nutritional index (PNI) as a predictive model for assessing disease activity in patients with systemic lupus erythematosus (SLE). By correlating these nutritional …
Sponsor: Sohag University • Aim: Diagnosis
Last updated Jun 27, 2026 12:33 UTC
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Real-World REKOVELLE study launches for chinese IVF patients
Knowledge-focused Recruiting nowThis is a multi-centre prospective non-interventional trial to assess the pattern of use of REKOVELLE® in Women Undergoing In Vitro Fertilisation (IVF) or Intracytoplasmic Sperm Injection (ICSI) Procedures in Routine Clinical Practice. There will be approximately 2500 patients i…
Sponsor: Ferring Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Mozart makes better surgeons? study tests music during AI training
Knowledge-focused CompletedAt the Neurosurgical Simulation and Artificial Intelligence Learning Centre, we seek to provide surgical trainees with innovative technologies that allow them to improve their surgical technical skills in risk-free environments, potentially improving patient operative outcomes. T…
Sponsor: McGill University • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC