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116076 trials found · Page 4328 of 5804
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Scientists hunt for clues to better treat HPV throat cancer
Knowledge-focused Recruiting nowProspective pilot study, non-interventional, of a biological/radiological nature, which involves the collection of tissue samples, and blood from patients suffering from squamous cell carcinoma of the oropharynx OPSCC for detection of HPV-DNA/RNA and immuno-phenotypic analysis of…
Sponsor: Regina Elena Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Yale study investigates diuretic resistance in heart failure
Knowledge-focused Recruiting nowRandomized double-blind placebo-controlled crossover study design
Phase: PHASE1 • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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New syrup shows promise for soothing stubborn heartburn
Symptom relief CompletedThis study involves a medical device in the form of syrup, not yet on the market and tested for the first time in humans, named "FIBROIN SYRUP". The intended use is to reduce the GastroEsophageal Reflux Disease (GERD) symptoms such as heartburn, epigastric pain, irritative and no…
Phase: NA • Sponsor: Rose Pharma SA • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Home exercises improve asthma symptoms in young adults
Symptom relief CompletedThe aim of this study was to investigate the effects of breathing exercises and postural exercises via telerehabilitation on respiratory parameters, posture, and quality of life in young adults with asthma.
Phase: NA • Sponsor: Yeditepe University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Old drug, new trick: can spironolactone silence HIV?
Knowledge-focused ENROLLING_BY_INVITATIONThis is a prospective, interventional, exploratory clinical study designed to evaluate the pharmacokinetics, safety, and biological effects of spironolactone on the degradation of the XPB (ERCC3) protein and its potential impact on the HIV reservoir. Spironolactone is an FDA-appr…
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New study tests organized care for heart disease prevention
Disease control Recruiting nowThis study aims to evaluate cardiovascular risk factors, clinical characteristics, and outcomes in adult patients attending an outpatient cardiology clinic. The research focuses on identifying predictors of adverse cardiovascular events, optimizing risk stratification, and improv…
Phase: NA • Sponsor: Universidad Católica San Antonio de Murcia • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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How your outlook after a breathing crisis affects your mental health
Knowledge-focused Recruiting nowThe purpose of this observational study is to understand how adults who survive acute respiratory failure (ARF) and the people (usually family) who support ARF survivors after returning home think about the first 6 months of recovery. The study aims to find out if expectations ab…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Liver bacteria may hold key to new alcoholic hepatitis treatments
Knowledge-focused Recruiting nowAlcoholic hepatitis (AH) is a serious complication of alcoholic liver disease (ALD). The histological presentation of AH is characterized by neutrophilic lobular inflammation, macrovesicular steatosis, hepatocyte ballooning and necrosis and the presence of Mallory bodies. In case…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Lighter epidural may boost Moms' birth experience
Symptom relief Recruiting nowChildbirth is a special event for women. Maternal satisfaction regarding childbirth is quite important, that is why this factor has to be taken into account. A bad experience related to childbirth could lead to serious psychological and organic consequences such as postpartum dep…
Sponsor: Centre Hospitalier Régional Metz-Thionville • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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New heart device registry tracks Real-World results for 1,950 AFib patients
Knowledge-focused Recruiting nowThe PulseSelect™ PFA Global Registry is a prospective, global, multi-center, observational post-approval study. Subjects will be treated with the PulseSelect™ PFA System and followed according to SOC.
Sponsor: Medtronic Cardiac Ablation Solutions • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Can cheap hearing aids help those with memory problems?
Symptom relief Recruiting nowThe goal of this study is to better understand if, in patients with mild to moderate hearing loss who are also experiencing mild cognitive impairment (MCI) or Alzheimer's disease and related dementias (ADRD), Over-the-Counter (OTC) hearing aids: 1. improve communication 2. Wheth…
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Jun 26, 2026 18:52 UTC
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Can talking about sex after hysterectomy improve your love life?
Symptom relief CompletedSexuality is affected by several physiological, cultural, social, and psychological factors. Hysterectomy is one of the factors that affects sexuality. Evidence suggests that hysterectomy, affects the sexual function of women. Therefore, this study aimed to evaluate the effect of…
Phase: NA • Sponsor: Kutahya Health Sciences University • Aim: Symptom relief
Last updated Jun 26, 2026 12:37 UTC
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Breathing machine settings may boost chest therapy in ICU
Knowledge-focused Recruiting nowIn intensive care, respiratory physiotherapy is an integral part of the daily care of patients under invasive mechanical ventilation. Its goals are to improve the clearance of bronchial secretions to allow for the resolution of atelectasis and alveolar recruitment, thereby enhanc…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Wearable sensors could predict your anxiety and memory lapses
Knowledge-focused Recruiting nowThe purpose of this study is to look at how signals in the brain, body, and behavior relate to anxiety and memory function. This project seeks to develop the CAMERA (Context-Aware Multimodal Ecological Research and Assessment) platform, a state-of-the-art open multimodal hardware…
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Massive study aims to end debate on spleen injury treatment
Knowledge-focused Recruiting nowThe spleen is often injured when the body sustains trauma. This leads to bleeding. The bleeding can be stopped by a big operation cutting open the belly or a small hole in your groin where a blood vessel can be accessed and through which the bleeding can be stopped. We do not kno…
Sponsor: University Hospital Plymouth NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Eye-Tracking reveals gaze differences in kids with autism
Knowledge-focused CompletedTo examine whether the spatiotemporal organization of gaze strategies differs between children with autism spectrum disorder (ASD) and typically developing (TD) children during a staged joint attention interaction, and to identify at which phase differences emerge.
Sponsor: University of Electronic Science and Technology of China • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Coloring away the stress: mandala art calms NICU moms
Symptom relief CompletedThe aim of this study was to evaluate the effect of mandala painting activity on stress and anxiety levels in mothers whose babies were hospitalized in the neonatal intensive care unit (NICU).
Phase: NA • Sponsor: Istanbul Medeniyet University • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Who gets heart rhythm treatment? new study explores social barriers
Knowledge-focused CompletedAtrial fibrillation is the most common arrhythmia with a prevalence of 1 to 4% and constitutes a major health problem both on an individual level (impaired quality of life, heart failure, stroke, hospitalization, excess mortality) and collective level (cost, use of resources). N…
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Can a senior center program help older adults with diabetes move better?
Knowledge-focused CompletedThe purpose of this study is to explore strategies to effectively implement senior-center-based multilevel lifestyle interventions adapted from evidence-based lifestyle interventions to promote physical function and quality of life in diverse older adults with Type 2 Diabetes (T2…
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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BRIUMVI under the microscope: Real-World MS registry launches
Knowledge-focused Recruiting nowThe purpose of this study is to evaluate safety, effiectiveness, and to gain insight into the treatment experience of participants prescribed BRIUMVI® (ublituximab-xiiy) in the real-world setting
Sponsor: TG Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC