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127005 trials found · Page 4254 of 6351
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New diabetes drug HMS1005 enters first human tests
Disease control Recruiting nowThe study is to assess the safety, pharmacokinetics, and pharmacodynamic profile of HMS1005 in patient with diabetes
Phase 1 • Sponsor: Hua Medicine Limited • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Pricing pouches: will smokers switch for a lower price?
Knowledge-focused CompletedSmoking is a prominent public health issue. Traditional nicotine replacement therapy suffers from being a poor substitute for cigarettes. Novel tobacco products, such as nicotine pouches, show promise as potential low-harm substitutes. Investigators wish to assess the substitutab…
Sponsor: William Middleton • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Can your smartwatch really track your workout? new study finds out.
Knowledge-focused Recruiting nowPhysical activity and its intensity level is a critical determinant of health. Digital Health Technologies, such as wearable accelerometers (wrist-worn watch-like devices), can provide researchers and clinicians with objective measures of activity intensity, duration, and effect …
Sponsor: Boston University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Which hearing implant packs the most punch? new study to find out
Knowledge-focused Recruiting nowThis study will look at how much sound amplification (gain) different bone-anchored hearing devices can provide. The goal is to understand if there are differences between devices and whether these differences affect how well the devices meet the hearing needs of users. Bone-anc…
Sponsor: Oticon Medical • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Can a simple varnish soothe sensitive teeth? new trial aims to find out
Symptom relief Recruiting nowThis randomized controlled clinical trial aims to determine whether different fluoride varnish formulations reduce dentin hypersensitivity (DH) in young adults diagnosed with DH. The primary purpose of this study is to evaluate the clinical effectiveness of two commercially avail…
Sponsor: University of Concepcion, Chile • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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VR study reveals how limb disuse warps your sense of reach
Knowledge-focused Recruiting nowThis study aims to evaluate the representation of action peripersonal space (PPS) in subjects suffering from unilateral segmental exclusion syndrome of the upper limb compared to healthy control subjects. Segmental exclusion is defined by non-use or under-use of a limb segment wi…
Sponsor: Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Scientists launch Decade-Long study to unravel mysterious inflammatory disease
Knowledge-focused Recruiting nowThe GRAMI-BIO study is a prospective single-centre cohort study to recruit 150 patients followed up in the the Bordeaux University Hospital. The total duration of the GRAMI-BIO study is ten years (five years of inclusion with five years of follow-up): Consecutive inclusion of pat…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Radiation-Free bone scan tested in kids
Knowledge-focused Recruiting nowThis study evaluates bone mineral density (BMD) in pediatric patients aged 5-18 years with conditions negatively affecting bone health, using REMS (Radiofrequency Echographic Multi Spectrometry), a non-invasive and radiation-free ultrasound technology. Bone health is crucial duri…
Sponsor: Meyer Children's Hospital IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Study reveals hidden risks for polyp regrowth after colonoscopy
Knowledge-focused CompletedThe objective of this retrospective cohort observational study is to identify variables related to the recurrence of colorectal lesions after snare polypectomy resection in colonoscopies. It also aims to evaluate the safety of the procedure. The main questions to be answered are:…
Sponsor: University of Sao Paulo • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Full-Body scans reveal hidden immune clues in long COVID
Knowledge-focused Recruiting nowThis study uses total-body \[¹⁸F\]F-AraG PET/CT imaging to investigate immune activation and vascular changes in individuals with post-acute sequelae of SARS-CoV-2 infection (PASC), also known as Long COVID. Participants will undergo dynamic PET/CT imaging along with blood biomar…
Early phase 1 • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Cancer drug RVU120 gets extended trial for ongoing patients
Disease control By invitation onlyThis is a multicenter rollover study to provide continued treatment to eligible participants previously enrolled in a RVU120 clinical study and to evaluate the safety of the treatment and record the time on treatment when continued under the same regimen as in the parent study. …
Phase 2 • Sponsor: Ryvu Therapeutics SA • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Can a website ease pancreatitis pain? small study tests online Self-Management
Symptom relief CompletedThis research study aims to evaluate the feasibility and acceptability of a web-based, self-guided, disease-specific self-management program tailored to individual health status profiles for patients with painful chronic pancreatitis.
Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New pain block could speed hernia recovery
Symptom relief Recruiting nowThis prospective, randomized clinical study aims to evaluate the effectiveness of the Transversus Abdominis Plane (TAP) block performed under direct laparoscopic vision in reducing postoperative pain and improving recovery after laparoscopic inguinal hernia repair using the TAPP …
Sponsor: University of Warmia and Mazury in Olsztyn • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Could tiny broccoli plants help obese breast cancer survivors?
Knowledge-focused Recruiting nowObesity can pose significant challenges to maintaining long-term health in cancer survivors by increasing their risk of cancer coming back. Eating a healthy diet is an important way to help manage weight and improve overall health. Broccoli microgreens (BMG) are young broccoli pl…
Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Volleyball players find relief by learning about pain
Symptom relief CompletedThis randomized controlled study investigated the effects of pain neuroscience education (PNE) on pain intensity, pain knowledge, and pain catastrophizing in elite volleyball players with chronic shoulder pain. Participants were assigned to either a PNE group or a control group, …
Sponsor: Pamukkale University • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Magnetic heart scan may spot rare disease earlier
Knowledge-focused Recruiting nowThe primary objective of this observational study is to evaluate the utility of magnetocardiography (MCG) in diagnosing and monitoring disease progression in patients with amyloidosis, and to assess its effectiveness in comparison to other modalities, such as ECG.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Balloon or dilators? new study seeks better way to prepare for abortion procedure
Symptom relief Recruiting nowThe purpose of this study is to determine whether the overnight use of an FDA-cleared CRDB catheter is superior to the use of overnight osmotic dilators as is standard of care cervical preparation for patients presenting for dilation and evacuation (D\&E). The CRDB catheter is an…
Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Laughter yoga may lift Seniors' spirits, study hopes
Symptom relief Recruiting nowThe purpose of this study is to observe the effects of laughter yoga on psychological well-being and depressive symptoms in older adults.
Sponsor: Ankara University • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Smoke tree mouthwash takes on bad breath in braces
Symptom relief CompletedThe aim of this trial was to investigate the effect of Cotinus Coggygria mouthwash on halitosis using as proxy the levels of the Volatile Sulfur Compounds (VSCs), and the effect on plaque and gingival indices in adolescents undergoing orthodontic treatment with fixed conventional…
Sponsor: University of Athens • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Finger-Stick and phone app could replace needles for anemia in pregnancy
Diagnosis Recruiting nowThe project is a prospective observational study aimed to assess and to validate the use of point-of-care hemoglobin testing in pregnancy. Point-of-care hemoglobin testing has the potential to (1) increase access to hemoglobin monitoring in pregnancy in low resource settings, (2)…
Sponsor: Inova Health Care Services • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC