New diabetes drug HMS1005 enters first human tests

NCT ID NCT07568678

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial is testing a new drug, HMS1005, in 40 people with type 2 diabetes. The main goal is to check the drug's safety and how the body processes it. Researchers will also look at how it affects blood sugar levels over 24 hours. Participants will receive either the drug or a placebo, and neither they nor the doctors will know who gets what.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HMS1005

What this could lead to

If successful, this could lead to a new oral medication to help control blood sugar in people with type 2 diabetes.

What could go wrong

This is an early phase 1 trial with only 40 participants, so it is primarily checking safety. The drug may not work well or could have side effects. Much more testing is needed before it could become a treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for TYPE 2 DIABETES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Pharmacology of Miami

    RECRUITING

    Miami, Florida, 33172, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••