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116076 trials found · Page 4242 of 5804
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Simple ultrasound may spot lung trouble in preterm infants early
Knowledge-focused Recruiting nowBronchopulmonary dysplasia (BPD) is one of the most common and severe complications of extreme prematurity, affecting approximately 40% of infants born before 28 weeks of gestation. Despite advances in neonatal care and improved survival rates for extremely preterm infants, the i…
Sponsor: Azienda USL Reggio Emilia - IRCCS • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
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AI coach helps nurses fight emotional eating
Symptom relief CompletedNurses with overweight and female gender characteristics often experience disruptions in their eating behaviors due to stressful working conditions. These disruptions can lead to physical and psychosocial problems (Nicholls et al., 2017). Studies have shown that guided self-help …
Phase: NA • Sponsor: Dokuz Eylul University • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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New fillers aim to smooth wrinkles and restore volume – study underway
Symptom relief OngoingThe aim of the study is to verify safety and performance of Semical dermal fillers according to real-world data.
Sponsor: Semikal Technology • Aim: Symptom relief
Last updated Jun 26, 2026 15:10 UTC
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New nerve block could replace standard pain injection for hip surgery
Symptom relief Recruiting nowCurrently, the analgesic standard of care for patients undergoing total hip arthroplasty (THA) at our centre is intraoperative infiltration with a solution of local anesthetic, morphine (opioid), and ketorolac (nonsteroidal anti-inflammatory drug - NSAID). If a patient has a cont…
Phase: NA • Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Symptom relief
Last updated Jun 26, 2026 18:04 UTC
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Eye infection aftermath: scientists map hidden blood vessel damage
Knowledge-focused Recruiting nowThis study aims to describe and investigate vascular changes associated with exogenous endophthalmitis, as well as to create a photo library where they are evidenced
Sponsor: Asociación para Evitar la Ceguera en México • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:41 UTC
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Spinal zap trial offers hope for rare stiffness disease
Symptom relief CompletedThe purpose of this prospective pilot study is to gather preliminary evidence evaluating spinal cord stimulation (SCS) as a potential therapy for the treatment of rigidity and painful spasms in patients with stiff person syndrome (SPS), a rare autoimmune neurological condition. T…
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Which pain block works best for hernia surgery? new study aims to find out
Symptom relief Recruiting nowPatients will be called to the operating room one hour before surgery and no premedication will be applied before coming to the operating room. Patients in both groups who are taken to the block room will be administered 1-2 mg iv midazolam for sedation. M TAPA block will be appl…
Phase: NA • Sponsor: Erzurum Regional Training & Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Heart surgery brain risk: could vein backup be the culprit?
Knowledge-focused Recruiting nowPostoperative delirium (POD) is an acute brain dysfunction characterized by inattention, impaired consciousness, and cognitive and orientation disturbances, and is a common complication after cardiac surgery. The high incidence of up to 52% of POD in cardiac surgery patients lead…
Sponsor: Zhuan Zhang • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Scientists probe the chemistry of tooth pain and stress
Knowledge-focused CompletedThis observational cross-sectional study is designed to evaluate pulpal and salivary levels of Substance P (SP) and Calcitonin Gene-Related Peptide (CGRP) in individuals with and without dental pain. The study aims to assess the associations between neuropeptide levels, pain seve…
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Could a lower dose of Clot-Buster be safer for lung infections?
Symptom relief Recruiting nowObjectives: A pilot study to assess the feasibility of a randomization trial protocol comparing low (2.5mg) and standard (10mg) doses of intrapleural tissue plasminogen activator (tPA) with deoxyribonucleases (DNase) in unresolved pleural infection. Hypothesis: The proposed rand…
Phase: PHASE2, PHASE3 • Sponsor: Chinese University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Which block works best for hernia pain? new study aims to find out
Symptom relief Recruiting nowIt is planned to compare the postoperative analgesic efficacy of the Transversalis Fascia Plane Block and the anterior Quadratus Lumborum Block in elective inguinal hernia surgeries.
Phase: NA • Sponsor: Gaziosmanpasa Research and Education Hospital • Aim: Symptom relief
Last updated Jul 09, 2026 00:00 UTC
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Acne breakthrough? ear acupressure boosts standard Gel's power
Symptom relief CompletedAcne vulgaris is a common chronic inflammatory skin condition that can significantly affect quality of life. Standard treatments such as topical retinoids are effective but may not fully control symptoms in all patients. This study evaluated the effectiveness of auricular acupre…
Phase: NA • Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Can remote rehab help lung patients breathe easier?
Symptom relief OngoingThe purpose of this pilot randomized clinical trial is to evaluate the willingness, acceptance, adherence and signs of benefits of structured home-based pulmonary rehabilitation (HPR) and supervised pulmonary tele-rehabilitation (PTR) on respiratory symptoms, quality of life, fun…
Phase: NA • Sponsor: Copenhagen University Hospital, Hvidovre • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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New 3-in-1 test for COVID, flu, and RSV put to the test
Diagnosis CompletedThe purpose of this clinical trial is to demonstrate the clinical performance of the VitaSIRO solo™ SARS-CoV-2/Flu/RSV Assay in detecting SARS-CoV-2, Flu A, Flu B and RSV in symptomatic population. The primary aim is to determine the PPA/NPA against a comparator assay. The second…
Sponsor: Credo Diagnostics Biomedical Pte. Ltd. • Aim: Diagnosis
Last updated Jun 27, 2026 11:03 UTC
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Gadget + gym: new combo tackles office neck pain
Symptom relief CompletedThe goal of this clinical trial is to investigate the effects of wearable postural feedback devices added to exercise approach on neck pain and proprioception in office workers with nonspecific chronic neck pain. H0: The effects of wearable postural feedback devices added to exe…
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Emergency vs. planned stoma surgery: which leads to better quality of life?
Knowledge-focused ENROLLING_BY_INVITATIONThe aim is to compare functional outcome and or quality of life in patients with a stoma that was constructed as an emergency procedure with patients where a stoma was created as a planned procedure. To do this data will be retrieved from the Swedish Patient Register to identify …
Sponsor: Eva Haglind, MD, PhD, professor • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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New pilot study tests In-Utero treatment for rare birth defect
Knowledge-focused TerminatedThe goal of this pilot trial is to learn more about the role of Fetal Endotracheal Occlusion (FETO) as an intervention in fetuses with severe congenital diaphragmatic hernia (CDH). The research team will investigate the feasibility and safety of the FETO procedure, as well as det…
Phase: NA • Sponsor: Eyal Krispin • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Researchers dig into past ICU data to see if CO2 removal machine helps breathing failure patients
Knowledge-focused Recruiting nowThis is an observational study performed by retrospective review of data routinely collected for patients receiving low-flow extracorporeal carbon dioxide removal (ECCO2R) therapy in intensive care units (ICUs). Our aim is to firstly, describe the local practice in terms of patie…
Sponsor: Hong Kong University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Could 360-degree VR videos transform how doctors learn endoscopy?
Knowledge-focused CompletedThe study is a randomized-controlled cross-over study to evaluate the impact of integrating simulation-based teaching for gastrointestinal endoscopy for medical students. It will establish a novel pedagogy for teaching in a wide array of disciplines in healthcare settings. Buildi…
Phase: NA • Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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Veterans' fibromyalgia pain: can exercise and brain chemistry offer clues?
Knowledge-focused Recruiting nowFibromyalgia (FM) is a chronic pain condition that disproportionately impacts Veterans. Individuals diagnosed with FM patients experience lower self-esteem and positive affect, as well as greater levels of depression, anxiety, negative affect, and pain catastrophizing. Among thos…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC