Spinal zap trial offers hope for rare stiffness disease

NCT ID NCT06242678

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small pilot study tested whether spinal cord stimulation could reduce painful muscle rigidity and spasms in people with stiff person syndrome, a rare autoimmune condition. Two adults with the disease received temporary stimulation for up to 10 days, and researchers measured changes in pain, spasm frequency, sleep, and mood. The goal was to gather early safety and effectiveness data to guide future research.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Atrium Health Wake Forest Baptist

    Winston-Salem, North Carolina, 27157, United States

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