New fillers aim to smooth wrinkles and restore volume – study underway

NCT ID NCT07160777

Ongoing Symptom relief Sponsor: Semikal Technology Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study is testing hyaluronic acid dermal fillers to see if they safely improve facial aging signs like wrinkles, volume loss, and lip shape. 80 healthy adults are receiving injections in areas like the cheeks, lips, and around the mouth. Researchers will measure aesthetic improvement and satisfaction over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hyaluronic acid dermal fillers (Semical Dermal Filler Fine, Plus, Ultra, and Mesolifter)
What this could lead to: If successful, this could confirm that these fillers safely improve facial wrinkles, volume loss, and lip appearance.
What could go wrong: This is a single-center study with 80 people, so results may not apply to everyone. Fillers can cause temporary swelling, bruising, or rare complications like infection or lumps.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FACIAL AGING FACIAL WRINKLES AND RHYTIDES REDUCTION LIP AUGMENTATION AND CORRECTION OF PERIORAL RHYTIDS MARIONETTE LINES NASOLABIAL FOLD CORRECTION PERIORBITAL WRINKLES SKIN REJUVENATION VOLUME DEFECTS IN THE MID-FACE

Contacts and locations

Locations

Akdeniz University Hospital Dermatology Department Cosmetology Clinic

Antalya, 07100, Turkey (Türkiye)

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