Botox battle: which injection site lifts drooping mouth corners best?

NCT ID NCT07646886

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two injection sites for Botox to treat drooping mouth corners, a common sign of aging. 266 adults aged 18-60 will receive a single injection either in the upper or lower part of a specific mouth muscle. The goal is to see which spot works better and safer, and to create standard guidelines for doctors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Botulinum toxin type A (Botox)

What this could lead to

If successful, this trial could establish the best injection site for treating drooping mouth corners with Botox, providing clear guidelines for doctors.

What could go wrong

This is a phase 4 trial, so the treatment is already approved for other uses. However, results may vary by individual, and there is a risk of temporary weakness in nearby muscles or asymmetry.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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