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116076 trials found · Page 4123 of 5804
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Less is more: thousands skip unnecessary cancer scans in landmark study
Knowledge-focused Recruiting nowRationale: Until recently, the conventional strategy outlined by both national and international guidelines for managing non-dysplastic (ND) Barrett esophagus (BE), involved endoscopic surveillance at 3 to 5 year intervals, aiming to reduce mortality from esophageal adenocarcino…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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New nasal spray could ease Kids' surgery fears
Symptom relief Recruiting nowFor pediatric patients undergoing general anesthesia, poor anesthesia induction compliance often has adverse effects on individual behavior in the early postoperative period. Dexmedetomidine can reduce the cardiovascular responses and postoperative mental adverse reactions caused…
Phase: PHASE4 • Sponsor: Second Affiliated Hospital of Wenzhou Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Hidden costs of PANS: new study reveals financial toll of IVIG treatment
Knowledge-focused CompletedThe Economic Impact Study of IVIG treatment for PANS is a part of the Unhide™ Project, which is a research initiative developed by the Brain Inflammation Collaborative. Specifically, the Unhide™ project is a collection of investigations with the overall goal of better understandi…
Sponsor: Brain Inflammation Collaborative • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:31 UTC
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At-Home exercises may ease Sonographers' aching muscles
Symptom relief CompletedWork-related musculoskeletal disorders(WRMDs) are common among cardiac sonographers due to their nature of work. This study aims to find out the effectiveness of the telerehabilitation method in the management of WRMDs among cardiac sonographers. 38 cardiac sonographers diagnosed…
Phase: NA • Sponsor: Imam Abdulrahman Bin Faisal University • Aim: Symptom relief
Last updated Jun 26, 2026 16:19 UTC
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New gel shows promise for dark skin patches
Symptom relief CompletedThe purpose of this study is to demonstrate the safety and efficacy of Sirolimus 0.2% topical gel for patients with Acanthosis Nigricans
Phase: PHASE2 • Sponsor: Narrows Institute for Biomedical Research • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Gut bugs linked to early menopause?
Knowledge-focused OngoingIn order to study the community profile of the intestinal microbiome in women with ovarian dysfunction, as well as the relationship between the changes in the intestinal microbiota and sex hormones, this study recruited 30 women with ovarian dysfunction and 30 healthy women. Sequ…
Phase: EARLY_PHASE1 • Sponsor: Songling Zhang • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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New tooth sealant could protect Kids' molars even when wet
Prevention OngoingThe study group will consist of children aged 7-11 years who are systemically healthy and who apply to the Pediatric Dentistry Clinic of the Faculty of Dentistry, Afyonkarahisar Health Sciences University for routine dental treatment. In the study, fissure sealants will be appli…
Phase: NA • Sponsor: Afyonkarahisar Health Sciences University • Aim: Prevention
Last updated Jun 27, 2026 08:01 UTC
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Simple mouth exercises may help preterm babies feed sooner
Symptom relief Recruiting nowThis is a randomized controlled experimental study evaluating the effects of oral motor intervention and chronobiological approach to feeding model applied to preterm infants on feeding readiness, transition to total oral feeding and body weight.
Phase: NA • Sponsor: Aydin Adnan Menderes University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Massage showdown: which therapy eases piriformis pain best?
Symptom relief ENROLLING_BY_INVITATIONThis study aims to compare the effectiveness of Stecco Fascial Manipulation and Rolfing Structural Integration in treating Piriformis syndrome, focusing on special outcomes like pain severity and functional outcomes. comparison will be done to check the effectiveness of Stecco-f…
Phase: NA • Sponsor: Danyal Ahmad • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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New study aims to transform cancer survivor Follow-Up care
Knowledge-focused Recruiting nowFRAME is a patient-centered survivorship care model embedded in routine oncology visits. It consists of: (1) a pre-visit patient-reported questionnaire (FRAME-PRO), (2) a clinician-patient dialogue guided by the responses, and (3) a tailored management plan including stepped-care…
Phase: NA • Sponsor: Vejle Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New blood markers may help predict heart trouble in diabetes patients
Knowledge-focused CompletedType 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by impaired insulin action and increased cardiometabolic risk. Visceral adiposity, insulin resistance, systemic inflammation, and dyslipidemia play key roles in the development of cardiovascular disease…
Sponsor: Tokat Gaziosmanpasa University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Simple foot workouts could soothe fibromyalgia foot pain
Symptom relief CompletedThis quasi-experimental study was designed to evaluate the effects of an eight-week foot core training program on foot pain, foot function, and pressure pain sensitivity in individuals with fibromyalgia. Participants were recruited among individuals diagnosed with fibromyalgia ac…
Phase: NA • Sponsor: University of Valencia • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Brain and body boost: school program improves skills in kids with coordination challenges
Symptom relief CompletedThe goal of this clinical trial is to evaluate the efficacy of an Action Observation and Motor Imagery (AOMI) combined with Fundamental Movement Skills (FMS) intervention for children aged 7 to 11 years with Developmental Coordination Disorder (DCD). The main questions it aims to…
Phase: NA • Sponsor: Shanghai University of Sport • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Jaw pain relief? simple washout procedure shows promise in small study
Symptom relief CompletedThis study is designed as a prospective cohort study evaluating the effect of temporomandibular joint arthrocentesis on articular capsular width using ultrasonography. The study is being conducted at the Faculty of Dentistry, Van Yuzuncu Yil University, Turkey, in accordance with…
Phase: NA • Sponsor: Yuzuncu Yil University • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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New scanner could help measure ALS progression at home
Knowledge-focused Recruiting nowAmyotrophic lateral sclerosis (ALS) has been traditionally considered incurable and untreatable. But starting in the 1990s with the introduction of Riluzole, therapies are being discovered and ultimately approved for slowing disease progression. Many pharmaceutical companies cont…
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Foot skin graft may be better for webbed finger surgery in kids
Symptom relief CompletedCongenital syndactyly is a condition present at birth in which two or more fingers are joined together. Surgical correction was performed to separate the fingers, improve hand appearance, and support better hand function. After separation of the fingers, a skin graft is often nee…
Phase: NA • Sponsor: Sheikh Zayed Medical College • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Simple tricks to take the ouch out of blood tests
Symptom relief CompletedAim: This study was conducted to determine the effect of distraction techniques (breathing exercises and stress ball squeezing) applied to adults during blood collection on pain and anxiety. Materials and Methods: The sample consisted of 90 patients who applied for admission to t…
Phase: NA • Sponsor: Celal Bayar University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Could talk therapy boost brain function in schizophrenia?
Symptom relief CompletedThis pilot randomized controlled trial examined whether adding structured supportive psychotherapy to risperidone treatment is more effective than risperidone alone in improving cognitive function and reducing peripheral inflammation in stabilized inpatients with schizophrenia. …
Phase: NA • Sponsor: Hasanuddin University • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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Immune cell study may unlock kidney protection in type 1 diabetes
Knowledge-focused Recruiting nowThis is a cross-sectional study in patients with Type 1 diabetes (TID) and chronic kidney disease (CKD) to test if time in range (TIR) affects the degree of hyperglycemia required for monocyte activation, podocyte injury, and assess if monocyte activation is attenuated by glucago…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
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One shade fits all? new tooth filling aims to match any Child's tooth color
Disease control Completed* Use of tooth-coloured fillings is an essential part of Pediatric dentistry as most patients desire fillings which look like natural teeth. * Lately, there is a vast variety of shade-choices in filling materials which complicates colour matching procedure, increases cost and inc…
Phase: NA • Sponsor: Goa Dental College • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC