Virtual reality goggles could revolutionize MS mobility tests

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * A confirmed diagnosis of multiple sclerosis (MS) established by a neurologist, * Not being in a relapse phase and having no MS relapse within the past 6 months, * Aged between 18 and 60 years, * Disease severity within an Expanded Disability Status Scale (EDSS) range of 1-5 (mild to moderate functional impairment), * Visual, auditory, and vestibular functions sufficient to tolerate mixed reality-based applications, * Adequate cognitive capacity to actively participate in the study (e.g., Mini-Mental State Examination score ≥ 24), * Ability to read, understand, and follow instructions in Turkish, * Willingness to participate voluntarily in the study and provision of written informed consent. Exclusion Criteria: * Having experienced a multiple sclerosis relapse or undergone a change in MS-related treatment within the past 6 months, * Presence of severe musculoskeletal disorders (e.g., fracture, arthritis, advanced osteoarthritis, muscle tear) that may interfere with test performance, * Presence of severe cardiopulmonary disease (e.g., uncontrolled hypertension, heart failure, chronic obstructive pulmonary disease) or any medical condition that may pose a risk during exercise testing, * Risk of loss of balance or spatial disorientation in the mixed reality environment due to visual, vestibular, or auditory impairments, * Inability to perform functional tests due to severe spasticity, contractures, or orthopedic deformities, * History of epilepsy, migraine, or other neurological conditions that contraindicate the use of mixed reality or virtual reality devices, * Inability to understand test instructions due to cognitive impairment or severe mental health disorders (e.g., dementia, major depression, psychotic disorders), * Experiencing dizziness, nausea, or virtual reality-related symptoms (VR sickness) during testing, * Insufficient motivation or poor compliance that may hinder participation in the study.