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116076 trials found · Page 3964 of 5804
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New study aims to take the guesswork out of returning to sports after knee replacement
Knowledge-focused Recruiting nowThe ability to return to sports after joint arthroplasty is increasingly becoming an important factor for patients in terms of their perceived quality of life. In sports orthopaedics, standardized functional tests have already been established - particularly for anterior cruciate…
Phase: NA • Sponsor: Technical University of Munich • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:05 UTC
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Uterine distension differences may shed light on infertility
Knowledge-focused Recruiting nowComparison of differences in distension by volumetric analysis of the uterus before and after distension between groups of infertile and apparently fertile women.
Sponsor: Centre Hospitalier de Saint-Denis • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:21 UTC
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New online program aims to ease caregiver stress in rare disease
Symptom relief ENROLLING_BY_INVITATIONThe goal of this pilot study is to determine the feasibility, acceptability and impact of a brief behavioral intervention - the "Well-Beans for Caregivers" program, for adult caregivers of individuals with tuberous sclerosis complex (TSC) of any age. The main questions of the stu…
Phase: NA • Sponsor: Vrije Universiteit Brussel • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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New anesthesia method studied for safer lung surgeries
Knowledge-focused CompletedThis prospective observational study aims to evaluate the effects of low-flow sevoflurane anesthesia on respiratory mechanics, gas exchange, and postoperative pulmonary function in patients undergoing one-lung ventilation (OLV) during thoracic surgery. The study will compare pati…
Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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New toothpaste aims to soothe sensitive teeth in seconds
Symptom relief CompletedThis randomized controlled clinical trial evaluates the effectiveness of a biomimetic hydroxyapatite-based toothpaste and mouthwash in reducing dental sensitivity in patients with gingival recession. A total of 100 participants will be randomly assigned to two groups. The control…
Phase: NA • Sponsor: University of Pavia • Aim: Symptom relief
Last updated Jun 26, 2026 18:36 UTC
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Frailty may signal kidney trouble in transplant patients
Knowledge-focused Recruiting nowThe aim of the study is to assess prevalence of frailty among renal transplant recipients in Alexandria University Hospitals and to study the relation between frailty and chronic allograft dysfunction.
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:33 UTC
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Which pain block works best after lung surgery?
Symptom relief CompletedThis prospective observational study aims to compare the effectiveness of Edge Laminar Block (ELB) and Serratus Posterior Superior Intercostal Plane Block (SPSIPB) in managing postoperative pain after Video-Assisted Thoracoscopic Surgery (VATS). The study will evaluate postoperat…
Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Not drinking enough water? study reveals hidden effects on aging bodies
Knowledge-focused Recruiting nowOur goal is to determine whether hydration status influences inflammation, and overall physiological performance in adults aged 45-65. Aim 1: The effects of 4-day mild dehydration followed by 4-day rehydration (defined as approximately 2-3% body mass loss) on H2O2, upstream infl…
Phase: NA • Sponsor: Texas Tech University • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:43 UTC
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Tooth pain relief: steroid injection may beat placebo after root canal
Symptom relief OngoingThis randomized controlled trial aims to compare the effectiveness of supra periosteal injection of dexamethasone versus placebo in reducing post operative pain in teeth diagnosed with symptomatic irreversible pulpitis. A total of 44 patients will be randomly assigned into two gr…
Phase: NA • Sponsor: College of Physicians and Surgeons Pakistan • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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New mix might ease root canal pain faster
Symptom relief OngoingThis randomized controlled trial aims to compare the effectiveness of calcium hydroxide mixed with 0.2% chlorhexidine digluconate versus calcium hydroxide mixed with saline as intracanal medicaments in reducing postoperative pain in patients with apical periodontitis. A total of …
Phase: NA • Sponsor: Aqsa Afzal • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Ovarian cancer study reveals hidden struggles of patients and caregivers
Knowledge-focused TerminatedFilling the gap in Canadian evidence on the burden of PROC on QoL is essential. It will help better understand the impact of PROC on multiple aspects of the lives of patients and their caregivers and the real-life hurdles faced by PROC patients and their caregivers. The outputs o…
Sponsor: PeriPharm • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Dialysis water watchdog: new device spots hidden dangers in real time
Diagnosis CompletedThis study validates a novel, continuous, and instantaneous water quality monitoring method, the "Pure Water Eye," for hemodialysis (HD) systems. Current periodic testing leaves patients vulnerable to acute, severe complications like hemolysis due to sudden, undetectable failures…
Sponsor: Usak State Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 07:59 UTC
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New oxygen monitor may keep lungs open during robotic surgery
Knowledge-focused CompletedThis single-center randomized controlled trial aims to evaluate whether intraoperative monitoring using the Oxygen Reserve Index (ORI) reduces the incidence of postoperative atelectasis, as assessed by lung ultrasound (LUS), in adult patients undergoing elective robotic surgery u…
Phase: NA • Sponsor: Antalya Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Laser and gel combo zaps tooth pain in new study
Symptom relief CompletedThe aim of this clinical trial is to evaluate the efficacy of the combined use of a diode laser and a potassium nitrate-based desensitizing gel in reducing dentin hypersensitivity in adult patients. Patients who meet the eligibility criteria and for whom informed consent has been…
Phase: NA • Sponsor: University of Pavia • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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New anchor method may simplify elbow fracture surgery for kids
Disease control Recruiting nowMedial epicondyle fractures of the humerus account for 11 to 20% of elbow fractures in children and adolescents. The therapeutic strategy remains controversial, ranging from conservative treatment to surgical fixation depending on the degree of displacement and joint instability…
Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Veterans with cancer get help discussing End-of-Life wishes in group sessions
Symptom relief Recruiting nowThe proposed research aims to engage participants in group educational sessions to facilitate learning of topics related to advanced care planning and to determine whether this approach is more effective than usual care alone.
Phase: NA • Sponsor: VA Palo Alto Health Care System • Aim: Symptom relief
Last updated Jul 22, 2026 00:00 UTC
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Vitamin e + painkiller: a new hope for period pain?
Symptom relief CompletedThe goal of this clinical trial is to determine whether adding vitamin E to mefenamic acid reduces menstrual pain more effectively than mefenamic acid alone in women with primary dysmenorrhea. Primary dysmenorrhea refers to painful menstrual cramps that occur without an underlyin…
Phase: PHASE4 • Sponsor: Nishtar Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Simple breathing test may predict oxygen danger during lung surgery
Knowledge-focused ENROLLING_BY_INVITATIONPatients undergoing thoracic surgery with one-lung ventilation (OLV) are prone to hypoxemia, which is primarily attributable to pulmonary ventilation-perfusion (V/Q) mismatch. This study will preoperatively assess the distribution of pulmonary ventilation under spontaneous breath…
Sponsor: Peking University People's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New mesh technique could boost dental implant success in thin jawbones
Disease control Recruiting nowTwenty posterior maxillary edentulous sites requiring open sinus augmentation for staged dental implant placement will be studied. Group I (study group) the maxillary sinus membrane will be elevated using titanium mesh fixed by bone screws. Group II (control group) will have stai…
Phase: NA • Sponsor: Suez Canal University • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New study aims to make dental extractions Pain-Free by testing better anesthetics
Symptom relief Ongoingpalatal anesthesia remains one of the greatest fears of patients as well as being painful for the patient and bothersome for the dentist .Research is still ongoing to find the best anesthetic agent that achieves the highest success rate of anesthesia and pain control without the …
Phase: NA • Sponsor: Tishreen University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC