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116076 trials found · Page 3955 of 5804
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Trauma tied to fibromyalgia? new study investigates
Knowledge-focused ENROLLING_BY_INVITATIONAdverse experiences, such as exposure to stressful or traumatic events, have been consistently associated with immune system dysfunction, accelerated inflammatory processes, and an increased risk of developing musculoskeletal symptoms, as well as autoimmune and rheumatologic dise…
Sponsor: National Institute of Medical Sciences and Nutrition, Salvador Zubiran • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Could a tiny tablet ease both heavy drinking and PTSD?
Symptom relief Recruiting nowThe overall objective of the proposed study is to determine if Dexmedetomidine HCl (BXCL501) is safe for treatment of alcohol use disorder (AUD) with comorbid posttraumatic stress disorder (PTSD) in an outpatient setting and also shows potential signals of efficacy thereby suppor…
Phase: PHASE1 • Sponsor: Pharmacotherapies for Alcohol and Substance Use Disorders Alliance • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Remote rehab: stroke patients try video therapy at home
Symptom relief CompletedThe objective of this randomized clinical trial is to evaluate the effects of using telerehabilitation (remote care) by occupational therapists on improving the performance and recovery of patients within the Brazilian Unified Health System (SUS) who have suffered a stroke and ar…
Phase: NA • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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New web tool aims to empower patients on multiple medications
Knowledge-focused Recruiting nowRationale: In current clinical practice, polypharmacy and patient empowerment are critical yet often overlooked. Polypharmacy, the chronic use of five or more drugs, poses risks such as adverse drug reactions and decreased medication adherence, especially in elderly and multimorb…
Phase: NA • Sponsor: Leiden University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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New registry study aims to unlock secrets of diabetic foot ulcers
Knowledge-focused Recruiting nowThis study examines the demographic, clinical, and laboratory characteristics of patients with diabetic foot ulcers admitted to 5 Azar Hospital, Gorgan, in 2024. By analyzing factors such as Hb, WBC, HbA1C, ESR, and CRP in relation to ulcer severity, the study aims to identify pr…
Sponsor: Golestan University of Medical sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Can a phone app boost prostate cancer screening in black men?
Knowledge-focused Recruiting nowProstate cancer is the most diagnosed cancer in African American men and the second-leading cause of cancer-related death. The prostate-specific antigen (PSA) test is an early detection screening tool for prostate cancer, however, knowledge about prostate cancer and screening ben…
Phase: NA • Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Hidden heart risk: Pre-Hypertension common in kids with type 1 diabetes?
Knowledge-focused Ongoingblood pressure of diabetic patients will be measured
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:27 UTC
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Talking away loneliness: new study tests short therapy for rural isolation
Symptom relief Recruiting nowThis study aims to enroll 65 participants who will be assigned to one of two groups. Each group will receive an intervention consisting of six weekly sessions of 40-60 minutes each. Eligibility includes residing in an agricultural area and reporting loneliness or feeling alone or…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New diabetes pill tested in chinese patients – early safety results expected
Disease control CompletedThe main purpose of this study is to investigate LY3549492 in Chinese participants with type 2 diabetes. Participation in the study will last about 18 weeks.
Phase: PHASE1 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Knee surgery recovery gets a digital boost: new app tested in 448-Patient trial
Symptom relief Recruiting nowTraumatic injury to the knee joint, such as rupture of the anterior cruciate ligament (ACL), can compromise the voluntary activation capacity of the quadriceps despite the anatomical integrity of the nerve and muscle structures responsible for contraction. This phenomenon is comm…
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Tiny brain probe reveals thinking secrets in Parkinson's patients
Knowledge-focused Recruiting nowThis study is being done to the determine the ability and utility of using the Neuropixels probes in the human brain. A Neuropixels probe will be inserted into and removed from the brain of awake human patients who are undergoing awake Deep Brain Stimulation (DBS) surgery.
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:31 UTC
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Toothpaste showdown: which paste best repairs tiny tooth cracks?
Disease control Recruiting nowThis randomized controlled clinical trial aims to evaluate the efficacy of two commercially available toothpastes containing hydroxyapatite in the remineralization of early enamel lesions. The study compares Biorepair® Total Protection Plus, which contains biomimetic microRepair …
Phase: NA • Sponsor: University of Pavia • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New nerve block could cut opioid use for kidney donors
Symptom relief Recruiting nowThis study aims to evaluate whether a regional anesthesia technique called the transversalis fascia plane block (TFPB) can improve pain control after hand-assisted laparoscopic donor nephrectomy (HALDN), a minimally invasive surgery performed in living kidney donors. Although HA…
Phase: NA • Sponsor: Koç University • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Virtual reality boosts stroke rehab in Robot-Assisted walking study
Knowledge-focused Recruiting nowThis study evaluates a novel Virtual Reality (VR)-integrated visual feedback system designed to enhance limb propulsion during robot-assisted gait rehabilitation in individuals post-stroke. In collaboration with CUREXO, a rehabilitation robotics company, the system is embedded wi…
Phase: NA • Sponsor: The University of Texas Medical Branch, Galveston • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Magnesium before surgery may soothe Kids' Post-Op agitation
Symptom relief CompletedThis prospective randomized controlled study will be conducted to evaluate the effects of preoperative oral magnesium on the incidence and severity of emergence agitation in children undergoing adenotonsillectomy using sevoflurane anesthesia.
Phase: NA • Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Can a treadmill and feedback fix Post-Stroke walking?
Knowledge-focused Recruiting nowThis single-session study aims to evaluate a novel gait training protocol that integrates mechanical constraints and sensory feedback to enhance paretic leg propulsion in individuals post-stroke. The study will include 15 individuals who have experienced a stroke and 15 healthy a…
Phase: NA • Sponsor: The University of Texas Medical Branch, Galveston • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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VR relaxation cuts Pre-Exam jitters in nursing students
Symptom relief CompletedThe goal of this clinical trial is to evaluate whether a brief virtual reality (VR) relaxation session can reduce pre-exam stress levels among undergraduate nursing students enrolled in nursing courses. The participant population includes male and female nursing students, aged 2…
Phase: NA • Sponsor: University of Bisha • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Brain procedure may weaken immune defenses, study warns
Knowledge-focused OngoingIn our ICU, it could notice that patients with cerebral arterio-venous malformation (AVM) treated with embolization develop more severe Ventilator Associated Pneumoniae (VAP) compare to other patients hospitalized for neurological diseases. The Dimethylsulfoxyde (DMSO), the solve…
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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New iron formula could protect preterm infants from anemia
Prevention ENROLLING_BY_INVITATIONIron prophylaxis will be initiated at age of 2-3 weeks at a dose of 3mg/kg/day. Standard care group: will receive ferrous iron (Enrich oral drops(50mg/ml), one drop per kilogram of body weight daily. Daily Liposomal group iron: will receive liposomal iron (Novofer (8mg/ml)) ever…
Phase: PHASE1 • Sponsor: Ain Shams University • Aim: Prevention
Last updated Jun 27, 2026 14:02 UTC
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Nerve block during hysterectomy may boost post-surgery sleep quality
Symptom relief CompletedTo evaluate the effect of regional analgesic blocks (TAP or rectus sheath block) applied in addition to general anesthesia on postoperative sleep quality in patients undergoing total abdominal hysterectomy (RCSQ score).
Sponsor: Haseki Training and Research Hospital • Aim: Symptom relief
Last updated Jul 10, 2026 00:00 UTC