New blood test may reveal bone health in kids on dialysis

NCT ID NCT07007338

Recruiting now Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new, non-invasive method using calcium isotope ratios in blood to see if the drug cinacalcet improves bone calcium balance in children aged 3-17 who are on dialysis and have secondary hyperparathyroidism. Researchers will measure these ratios before and three months after starting cinacalcet. The goal is to find a better way to monitor bone health without invasive procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cinacalcet
What this could lead to: If successful, this could provide a non-invasive way to monitor bone health in children on dialysis, helping doctors tailor treatments like cinacalcet more effectively.
What could go wrong: This is a very small, early-stage study (20 participants) that only measures a biomarker, not clinical outcomes. The isotope method is still experimental and may not translate into direct patient benefits.

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Conditions

The condition(s) this trial relates to.

renal osteodystrophy secondary hyperparathyroidism secondary hyperparathyroidism of renal origin

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHILDREN OVER 3 UNDERGOING DIALYSIS WITH SECONDARY HYPERPARATHYROIDISM

Contacts and locations

Locations

Hôpital Femme Mère Enfant
RECRUITING

Bron, 69500, France
Service de Néphrologie - Transplantation - Hémodialyse pédiatrique Hôpital Robert Debré
RECRUITING

Paris, 75019, France
Service de Néphrologie pédiatrique Hôpital Necker Enfants Malades
RECRUITING

Paris, 75012, France
Service de Pédiatrie CHU de Bordeaux
RECRUITING

Bordeaux, 33000, France
Service de pédiatrie 1 CHU Hautepierre
RECRUITING

Strasbourg, 67000, France
Service de pédiatrie multidisciplinaire CHU de Montpellier
RECRUITING

Montpellier, 34295, France
Unité de néphrologie pédiatrique, Hôpital Archet 2, CHU de Nice
RECRUITING

Nice, 06202, France

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