Can a simple cream soothe psoriasis? new trial tests Urea-Based lotions
NCT ID NCT07545902
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests two medical creams containing urea (20% and 40%) on people with mild plaque psoriasis or non-pustular palmoplantar psoriasis. Each participant applies the cream to one affected area and leaves a similar area untreated for comparison. The goal is to see if the creams reduce plaque severity after 4 or 8 weeks. The trial is small (35 people) and not yet recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PROXERA PSOMED 20 cream (20% urea) and PROXERA PSOMED 40 gel (40% urea)
What this could lead to
If successful, these creams could offer a simple, non-prescription option to reduce psoriasis plaques and palmoplantar symptoms.
What could go wrong
This is a small, early study with only 35 people. The creams may not work better than no treatment, and results may not apply to everyone with psoriasis.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Clinica Dermatologica Dipartimento di Medicina e Scienze dell'Invecchiamento Università G. D' Annunzio
Chieti, Italia, 66100, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••