Generic psoriasis cream could offer cheaper alternative to VTAMA®

NCT ID NCT06742957

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a generic tapinarof cream works as well as the brand-name VTAMA® cream for adults with plaque psoriasis. 560 participants used either the generic cream, the brand-name cream, or a placebo for 12 weeks. The goal was to see if the generic version is equally safe and effective at clearing or nearly clearing psoriasis patches.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tapinarof cream 1%

What this could lead to

If successful, this could show that a generic version of tapinarof cream is as safe and effective as the brand-name VTAMA®, potentially offering a lower-cost treatment option for plaque psoriasis.

What could go wrong

This is a completed Phase 3 trial, but results are not yet published. Even if the generic works similarly, it may not work for everyone, and side effects like skin irritation are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

psoriasis Skin Diseases, Papulosquamous skin disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • 12127

    Woodbury, New York, 11797, United States

  • Site 12101

    Bryant, Arkansas, 72022, United States

  • Site 12102

    Fremont, California, 94538, United States

  • Site 12103

    College Station, Texas, 77845, United States

  • Site 12104

    Miami, Florida, 33144, United States

  • Site 12105

    Louisville, Kentucky, 40241, United States

  • Site 12106

    Clarksville, Indiana, 47129, United States

  • Site 12107

    Scottsdale, Arizona, 85260, United States

  • Site 12108

    Chicago, Illinois, 60614, United States

  • Site 12109

    Las Vegas, Nevada, 89121, United States

  • Site 12110

    Dublin, California, 94568, United States

  • Site 12111

    Pomona, California, 91767, United States

  • Site 12112

    Dublin, California, 94568, United States

  • Site 12113

    Miami, Florida, 33175, United States

  • Site 12114

    Miramar, Florida, 33027, United States

  • Site 12115

    Fort Lauderdale, Florida, 33308, United States

  • Site 12116

    Miami, Florida, 33146, United States

  • Site 12117

    Houston, Texas, 77070, United States

  • Site 12118

    El Paso, Texas, 79925, United States

  • Site 12119

    Huntington Beach, California, 92647, United States

  • Site 12120

    Northridge, California, 91325, United States

  • Site 12121

    Rolling Meadows, Illinois, 60008, United States

  • Site 12122

    Greenwich, Connecticut, 06831, United States

  • Site 12123

    Merrillville, Indiana, 46410, United States

  • Site 12125

    Upper Saint Clair, Pennsylvania, 15241, United States

  • Site 12126

    Portland, Oregon, 97210, United States