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116076 trials found · Page 3284 of 5804
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Can a smaller dose of a drug ease the pain of pregnancy loss?
Symptom relief TerminatedMost patients seeking abortion care or management of pregnancy loss in the second trimester will lactate, which can be physically and emotionally painful. The efficacy of a one-time dose of cabergoline has been previously demonstrated to prevent breast symptoms for these patients…
Phase: PHASE2 • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jul 19, 2026 00:00 UTC
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Opioid breathing risks during sleep under the microscope
Knowledge-focused Not yet recruitingThe investigators are studying the impact that opioids have on breathing during sleep in healthy participants and those diagnosed with obstructive sleep apnea.
Phase: EARLY_PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New monthly shot for schizophrenia enters early human testing
Disease control Not yet recruitingThe purpose of this study is to assess the pharmacokinetics (PK), safety, and tolerability of AX251 long-acting injectable (LAI) administered as a single dose in patients with schizophrenia. The study will include sequential dose-escalation cohorts to evaluate different dose leve…
Phase: PHASE1 • Sponsor: Anxo Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Rural Teens' rights under the microscope: new study in egypt
Knowledge-focused Not yet recruitingThis community-based cross-sectional study aims to assess the fulfilment of adolescent rights in health, education, protection, and community participation among adolescents aged 15-19 years living in Beni Adi village, a rural community in Assiut Governorate, Egypt.
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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New group program aims to help brain injury survivors rejoin social life
Symptom relief Not yet recruitingThis study will first evaluate the feasibility of delivering the ENGAGE-TBI intervention in a community setting with adults with TBI.
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Could hormone drugs replace hernia surgery?
Disease control Recruiting nowThis is a prospective, single-center, three-arm Phase 1 safety and feasibility trial evaluating anti-estrogen therapy in men age 50 years and older with symptomatic unilateral inguinal hernias. Participants will be randomized to receive fulvestrant 250 mg intramuscularly, fulvest…
Phase: PHASE1 • Sponsor: Northwestern University • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Optical illusions could train social skills in psychosis
Symptom relief Not yet recruitingThis study aims to explore whether the observation of complex visual objects can help improve social cognition in people living with psychotic disorders. Social cognition refers to the ability to understand what others think, feel, or intend, and plays a key role in social relati…
Phase: NA • Sponsor: Hôpital le Vinatier • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Emotional smarts: a new way to boost your marriage?
Symptom relief Not yet recruitingThis study aims to examine the effects of Emotional Intelligence (EI) training on marital satisfaction and mental health among married adults in Dhaka city, Bangladesh. Emotional intelligence refers to the ability to recognize, understand, regulate, and manage emotions in oneself…
Phase: NA • Sponsor: University of Dhaka • Aim: Symptom relief
Last updated Jun 27, 2026 12:39 UTC
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New study aims to keep kidney transplant patients stronger while they wait
Knowledge-focused Not yet recruitingThis study looks at how the physical and emotional health of people changes while they wait for a kidney transplant. Waiting for an organ can take a long time. During this period, some patients become "frail." This means they lose strength and are at a higher risk for health prob…
Sponsor: Hospital del Mar • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Brain ultrasound trial aims to uncover clues in sick kids
Knowledge-focused Not yet recruitingThis study uses a non-invasive (external) ultrasound test called Transcranial Doppler (TCD) to measure how blood flows through the major arteries of the brain of children receiving care in the Pediatric Intensive Care Unit (PICU). TCD is already used for clinical reasons in many …
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Skin deep: european study probes the hidden emotional toll of skin diseases
Knowledge-focused Not yet recruitingThe European Society for Dermatology \& Psychiatry (ESDaP) studies the connection between the skin and the mind. Two previous studies of this type were conducted in 13 and 15 European countries, respectively. The first study assessed the psychological impact of skin diseases (anx…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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New combo test aims to spot tough airways before surgery
Diagnosis Not yet recruitingThe aim of this observational study is to evaluate the accuracy of the HMDR combined with the ULBT as a predictor of difficult laryngoscopy in obese patients undergoing elective surgery under general anesthesia, regarding: * Correlation of HMDR-ULBT values with Cormack-Lehane gr…
Phase: NA • Sponsor: Cairo University • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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Can mindfulness ease the trauma of childbirth workers?
Symptom relief Not yet recruitingThis study aims to examine the effect of a Mindfulness-Based Self-Compassion Program on self-compassion levels, secondary traumatic stress, and professional quality of life in midwives and nurses working in obstetrics. Healthcare professionals in this field are frequently exposed…
Phase: NA • Sponsor: Agri Ibrahim Cecen University • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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Life after drugs: new study to measure physical and mental health
Knowledge-focused Not yet recruitingThe aim of this study is to investigate physical and physicosocial well-being after quitting drug use.
Sponsor: Alanya Alaaddin Keykubat University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Could extra antibiotics help prolong pregnancy after early water break?
Disease control Not yet recruitingThe purpose of this study is to learn whether adding extra doses of azithromycin to the standard antibiotic treatment for preterm prelabor rupture of membranes may improve pregnancy outcomes for patients between 22 weeks and 28 weeks gestational age. Researchers will compare the…
Phase: PHASE4 • Sponsor: Alexa Henderson • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New antibiotic dosing method could cut infections after heart surgery
Prevention Not yet recruitingA randomized controlled trial on adults who underwent coronary artery bypass grafting (CABG) surgery. To evaluate the effectiveness of intraoperative continuous infusion (CI) of cefazolin compared with intermittent (INT) cefazolin administration in preventing surgical site infect…
Phase: PHASE4 • Sponsor: Helwan University • Aim: Prevention
Last updated Jun 27, 2026 14:02 UTC
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Body position may predict fluid needs during keyhole hysterectomy
Knowledge-focused Recruiting nowThis observational study investigates the predictors of Pleth Variability Index (PVI) changes in euvolemic patients undergoing laparoscopic-assisted vaginal hysterectomy (LAVH). The primary objective is to quantify changes in PVI (ΔPVI) across six intraoperative time points assoc…
Sponsor: Wonkwang University Hospital • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Could a Life-Skills program transform teen health in belize?
Knowledge-focused Not yet recruitingTHRIVE-Belize is a school-based program being developed to support the health and well-being of adolescents in the Toledo District of southern Belize. The program covers seven topics: communication and emotional regulation, healthy expressions of masculinity, sexual and reproduct…
Sponsor: University of Arizona • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Volleyball spikes under fatigue: study probes shoulder changes
Knowledge-focused Not yet recruitingThis study aims (1)to investigate the effects of repetitive functional overhead movements targeting shoulder and scapular muscles on glenohumeral and scapular kinematics and muscle activation during the arm cocking and acceleration of spiking, and changes in subacromial structure…
Sponsor: National Yang Ming Chiao Tung University • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Inhaled experimental drug targets tough lung infections
Disease control Not yet recruitingThis is a Phase 1a/1b study to test the safety, tolerability, microbiological response, and pharmacokinetics of inhaled Rev-56 compared to placebo in adult healthy participants and non-cystic fibrosis bronchiectasis (NCFB) patients with P. aeruginosa, respectively. Phase 1a (Par…
Phase: PHASE1 • Sponsor: Revagenix, Inc. • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC