New eczema pill shows promise in Mid-Stage trial

NCT ID NCT05399368

Terminated Symptom relief Sponsor: RAPT Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental daily pill called RPT193 for adults with moderate-to-severe atopic dermatitis (eczema) that didn't improve with topical creams. The goal was to see if it reduces skin redness, swelling, and itchiness over 16 weeks. The trial involved 229 participants and was stopped early, but results help researchers understand how well the drug works and its safety.

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Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

Locations

Acclaim Dermatology

Sugar Land, Texas, 77479, United States
Advanced Dermatology of the Midlands

Omaha, Nebraska, 68144, United States
Apex Clinical Research Center

Mayfield Heights, Ohio, 44124, United States
Arkansas Research Trials, LLC

North Little Rock, Arkansas, 72117, United States
Arlington Research Center Inc.

Arlington, Texas, 76011, United States
Beacon Clinical Research, LLC

Quincy, Massachusetts, 02169, United States
Cahaba Dermatology and Skin Health Center

Birmingham, Alabama, 35244, United States
California Dermatology & Clinical Research Institute

Encinitas, California, 92024, United States
Clinical Science Institute

Santa Monica, California, 90404, United States
Clinical Trial Network

Houston, Texas, 77074, United States
Clinical Trials Research Institute

Thousand Oaks, California, 91320, United States
Complete Dermatology

Sugar Land, Texas, 77479, United States
Dawes Fretzin Clinical Research Group, LLC

Indianapolis, Indiana, 46250, United States
DelRicht Research

Baton Rouge, Louisiana, 70809, United States
DermResearch

Austin, Texas, 78759, United States
Dermatology Research Associates

Los Angeles, California, 90045, United States
Dermatology Treatment and Research Center

Dallas, Texas, 75230, United States
Driven Research LLC

Coral Gables, Florida, 33134, United States
First OC Dermatology

Fountain Valley, California, 92708, United States
Fivenson Dermatology

Ann Arbor, Michigan, 48103, United States
Florida Academic Centers Research and Education, LLC

Coral Gables, Florida, 33134, United States
Forcare Clinical Research

Tampa, Florida, 33613, United States
Forest Hills Dermatology Group

Kew Gardens, New York, 11415, United States
Foxhall Research Center

Washington D.C., District of Columbia, 20016, United States
GSI Clinical Research

Margate, Florida, 33063, United States
Georgia Skin & Cancer Clinic

Savannah, Georgia, 31419, United States
Grekin Skin Institute

Warren, Michigan, 48088, United States
Grimes Center

Los Angeles, California, 90036, United States
Health Concepts

Rapid City, South Dakota, 57702, United States
Ichan School of Medicine at Mount Sinai

New York, New York, 10029, United States
Indiana Clinical and Translational Sciences Institute (CTSI) Clinical Research Center

Indianapolis, Indiana, 46202, United States
Integrative Skin Science and Research

Sacramento, California, 95815, United States
JUVA Skin & Laser Center

New York, New York, 10022, United States
Jordan Valley Dermatology Center

South Jordan, Utah, 84095, United States
LEADER Research

Hamilton, Ontario, L8L 3C3, Canada
Lenus Research & Medical Group, LLC

Sweetwater, Florida, 33172, United States
Marietta Dermatology Clinical Research, Inc.

Marietta, Georgia, 30060, United States
Markowitz Medical, PLLC

New York, New York, 10128, United States
Medisearch Clinical Trials

Saint Joseph, Missouri, 64506, United States
MetroBoston Clinical Partners

Brighton, Massachusetts, 02135, United States
Optima Research - Boardman

Boardman, Ohio, 44512, United States
Palm Beach Dermatology Group

Delray Beach, Florida, 33484, United States
Perseverance Research Center

Scottsdale, Arizona, 85254, United States
Premier Clinical Research

Spokane, Washington, 99202, United States
Progressive Clinical Research

San Antonio, Texas, 78213, United States
Red Maple Trials Inc.

Ottawa, Ontario, K1H 1E4, Canada
Schweiger Dermatology Group

Verona, New Jersey, 07044, United States
Schweiger Dermatology Group, PC Research Division

Columbia, Maryland, 21044, United States
SimcoDerm Medical and Surgical Dermatology Center

Barrie, Ontario, L4M7G1, Canada
Skin Care Physicians of Georgia

Macon, Georgia, 31217, United States
Skin Sciences PLLC

Louisville, Kentucky, 40217', United States
Skin Specialists PC (Schlessinger MD)

Omaha, Nebraska, 68144, United States
St. Joseph Dermatology and Vein Clinic

Saint Joseph, Michigan, 49085, United States
Studies in Dermatology, LLC

Cypress, Texas, 77433, United States
The Indiana Clinical Trials Center PC

Plainfield, Indiana, 46168, United States
University Dermatology and Vein Clinic

Darien, Illinois, 60561, United States
Velocity Clinical Research

North Hollywood, California, 91606, United States
Wallace Medical Group

Los Angeles, California, 90056, United States
West End Dermatology Associates

Richmond, Virginia, 23233, United States

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