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116076 trials found · Page 3143 of 5804
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Pill may replace shots for blood cancer patients, study finds
Disease control CompletedTreatment of higher-risk (intermediate, high and very high) Myelodysplastic Syndromes (MDS) according to the revised International Prognostic Scoring System (IPSS-R) who obtained a stable hematological response ( CR, PR) after subcutaneous azacitidine treatment. Azacitidine is a…
Phase: PHASE2 • Sponsor: University of Florence • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Virtual reality could help pinpoint the perfect exercise dose for dizziness relief
Symptom relief TerminatedThe purposes of this research are to 1) utilize virtual reality (VR) to evaluate the exercise dose required to improve symptoms in those with vestibular (dizziness) disorders, 2) compare VR vestibular exercises to standard exercises, and 3) compare exercise performance outcomes t…
Phase: NA • Sponsor: George Washington University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New screening tool may predict ACL surgery need after rehab
Knowledge-focused OngoingThe aim is to determine the sensitivity and specificity of a screening tool to identify patients who undergo ACL reconstruction (non-copers) after 3 months of standard rehabilitation following an anterior Cruciate ligament (ACL) injury.
Sponsor: Vejle Hospital • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Deep gum cleaning may boost quality of life for hemophilia patients
Disease control CompletedThis study aimed to evaluate the effect of non-surgical periodontal treatment (NSPT) on oral health-related quality of life in patients with hemophilia using the Oral Health Impact Profile-14 (OHIP-14) questionnaire. In addition, clinical periodontal parameters and demographic ch…
Phase: NA • Sponsor: Karadeniz Technical University • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Ultrasound could spot deadly lung disease in scleroderma patients early
Diagnosis CompletedDiffuse interstitial lung disease (PID) is the leading cause of death in systemic scleroderma (SSc). Major progress has recently been made in its therapeutic management. Early diagnosis is essential to optimize this management. Current diagnostic techniques are based on high-reso…
Phase: NA • Sponsor: University Hospital, Tours • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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Laser vs. balloon: which works best for narrowed windpipe?
Disease control TerminatedMulticenter randomized controlled trial comparing endoscopic laser resection vs dilatation in benign tracheal stenosis.
Phase: NA • Sponsor: Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Cialis for weight loss? study tests Fat-Burning effects
Knowledge-focused CompletedThis is a randomized, double-blinded, placebo-controlled study of the effects of PDE5 inhibition with tadalafil on adipose tissue in obese individuals. Adipose metabolism will be measured using magnetic resonance imaging (MRI) scans and by aspirating a small amount of adipose to …
Phase: PHASE2 • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Osteopathic touch shows promise for depression relief
Symptom relief Completedparticipants will be receiving OMT 1x/week for 8 weeks. Each appointment with be a duration of 30 minutes. Patients will be required to fill out PHQ-9 and SSS-8 questionnaires before beginning the study and following the conclusion of the study.
Phase: NA • Sponsor: Corewell Health South • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Scientists lock 15 people in a cave for 40 days — no clocks, no sunlight
Knowledge-focused CompletedThe objectives of this scientific expedition are: a/ Evaluation of temporal cognitive perception and collective synchronization in a temporally anomalous universe (underground environment), b/ Influence of group living on the endogenous circadian rhythmicity of the central biolog…
Phase: NA • Sponsor: University Hospital, Caen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Real-World study examines Isavuconazole's effectiveness against deadly fungal infections
Knowledge-focused CompletedThis is a non-interventional medical chart review study aiming to examine the effectiveness, safety, and treatment patterns of isavuconazole in 5 European countries (France, Germany, Italy, Spain, and United Kingdom). Eligible patients are adults who have been treated with isavuc…
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Sperm survival test could make IVF safer by spotting toxic lab tools
Knowledge-focused CompletedThe main embryotoxicity quality controls are the mouse embryo test (MEA = Mouse Embryo Assay) and the human sperm survival test (HSSA = Human Sperm Survival Assay). The HSSA test measures the survival (or mobility) of human sperm after exposure to the tested consumable for a pred…
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Which method helps cancer patients best? new study tests palliative care delivery
Symptom relief OngoingThis trial studies the delivery of the ENABLE palliative care program by two different methods called a Virtual Learning Collaborative or Technical Assistance for patients with advanced cancer and their caregivers. Palliative care is specialized medical care for people with a ser…
Phase: NA • Sponsor: University of Rochester NCORP Research Base • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Can a remote parenting program tame toddler tantrums? new study investigates.
Prevention OngoingThe PANTHERS (Parents And iNfants Together in Home-based Early Remote Services) Projects is a study funded by the National Institute of Child Health and Human Development to evaluate the efficacy and maintenance of a remote home-based preventive intervention, the Infant Behavior …
Phase: NA • Sponsor: Florida International University • Aim: Prevention
Last updated Jun 27, 2026 08:01 UTC
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Could a plant hormone help tame prediabetes?
Symptom relief CompletedThe purpose of this study is to determine the effects of oral abscisic acid (ABA) on glucose metabolism in subjects with defined prediabetes.
Phase: PHASE2 • Sponsor: AdventHealth Translational Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Could aspirin or ibuprofen help beat TB faster?
Disease control TerminatedThe purpose of this study is to assess the efficacy and safety of 2 repurposed drugs (acetylsalicylic acid and ibuprofen), for use as adjunct therapy added to, and compared with, the standard of care (SoC) WHO-recommended TB regimen in drug-sensitive (DS) and multi-drug resistant…
Phase: PHASE2 • Sponsor: Fundació Institut Germans Trias i Pujol • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Double PET scan may unlock secrets of gut tumors
Knowledge-focused OngoingThe variable clinical outcome of patients with G2 \& G3 well diff GEP-NETs makes the selection of an optimal treatment strategy challenging. Initial data suggests that high DOTATATE uptake and low FDG uptake are suggestive of low grade disease, with an indolent course. Converse…
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New combo pill aims to slash dangerous blood fats in High-Risk patients
Disease control CompletedThe purpose of this study is to evaluate the efficacy of Cipros 20 association in the treatment of dyslipidemia treatment.
Phase: PHASE3 • Sponsor: EMS • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Enzyme therapy shows promise for rare gaucher type 3 in small chinese study
Disease control CompletedPrimary Objective * To evaluate the efficacy on hematologic manifestations of imiglucerase treatment in Chinese patients who are diagnosed as Gaucher disease type Ⅲ * To evaluate the safety profile of imiglucerase in maximum dose in the label (60U/kg, IV biweekly) in Chinese pat…
Phase: PHASE4 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 26, 2026 17:18 UTC
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Family coaching boosts sleep apnea treatment use in kids with down syndrome
Symptom relief CompletedDetermine the efficacy of family-informed intervention (INT) vs standard clinical care over a period of twelve months in children with obstructive sleep apnea and Down Syndrome.
Phase: NA • Sponsor: University of Miami • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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Can a chatbot help young people navigate cancer risk?
Knowledge-focused OngoingThis research is being done because there is a need to improve cancer risk communication and decision-making among adolescents and young adults. In this study, the investigators are looking at whether using a chatbot and online portal for cancer risk information helps improve com…
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC