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127005 trials found · Page 2622 of 6351
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Could a steroid injection after knee surgery cut opioid use?
Symptom relief Recruiting nowThe goal of this clinical trial is to find out which type of steroid medicine, when added to a standard pain-control injection during total knee replacement surgery, works best at reducing pain, limiting opioid use, and improving recovery in adults undergoing surgery for severe k…
Phase 2/3 • Sponsor: Walter Reed National Military Medical Center • Aim: Symptom relief
Last updated Aug 21, 2026 00:00 UTC
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When to zap? new trial seeks optimal timing for brain stimulation after stroke
Symptom relief Not yet recruitingThis randomized, double-blind, sham-controlled clinical trial investigates how the timing of transcranial direct current stimulation (tDCS) influences functional recovery during acute stroke rehabilitation. 198 hospitalized patients with confirmed acute stroke will be randomly as…
Sponsor: University of Liege • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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Medical cannabis studied as a remedy for chemo side effects
Symptom relief Not yet recruitingThe goal of this observational study is to evaluate the associations between patient-directed medical cannabis use and chemotherapy-induced nausea and vomiting (CINV), as well as other treatment-related symptoms, among patients receiving chemotherapy that is known to cause nausea…
Sponsor: University of Rochester • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Robot-Only lung surgery may cut costs without sacrificing safety
Disease control Not yet recruitingRobotic-assisted thoracoscopic surgery (RTS) is safe and effective for patients with early-stage non-small cell lung cancer (NSCLC). During RTS, division, dissection, and sealing of lung tissue, bronchi, and blood vessels can be performed using handheld staplers with assistance f…
Sponsor: St. Joseph's Healthcare Hamilton • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Could a bone marrow boost help heal torn hips?
Disease control Not yet recruitingThe BoneMarrowHip study is a single-blind, randomized, single-center trial. Through this study, the clinical results of patients treated during hip arthroscopy surgery with autologous bone marrow infiltration taken from the ipsilateral iliac crest will be evaluated and compared, …
Sponsor: Istituto Ortopedico Rizzoli • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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Can blood tests predict severe diarrhea from breast cancer drug?
Knowledge-focused Not yet recruitingRemarkable progress has recently been made in the treatment of locally advanced, hormone receptor-positive, HER2-negative breast cancer with a high risk of recurrence, thanks to the addition of abemaciclib to endocrine therapy. This combination has led to a significant improvemen…
Phase 4 • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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Marijuana pill may boost CPAP use in sleep apnea patients
Symptom relief Not yet recruitingThe purpose of this study is to determine if oral dronabinol prior to sleep can improve CPAP adherence and sleep quality in humans. We also seek to determine if combination therapy of CPAP and pre-sleep dronabinol is associated with improved BP regulation. We will also explore BP…
Phase 2/3 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Aug 15, 2026 00:00 UTC
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Drama therapy tested as a new way to lift teen depression
Symptom relief Recruiting nowThe research aims to investigate the effectiveness of playback theatre program on improving mental health for adolescents and youth. This study adopts a multicentre randomized control trial two arms research design. A randomised controlled trial will compare a typical 7-session …
Sponsor: City University of Hong Kong • Aim: Symptom relief
Last updated Sep 10, 2026 04:00 UTC
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Could tiny exercise bursts improve sleep apnea symptoms?
Symptom relief Not yet recruitingObstructive Sleep Apnea Syndrome (OSA) is a condition characterized by repeated pauses or reductions in breathing during sleep, which can negatively affect sleep quality, daytime functioning, and physical capacity. Although regular exercise is known to have beneficial effects in …
Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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Lavender scent may sharpen memory in aging brains
Symptom relief Not yet recruiting1. To analyze the therapeutic effects of lavender aromatherapy on memory function and overall cognitive function in older adults with Mild Cognitive Impairment (MCI); 2. To analyze whether lavender aromatherapy improves executive function, language ability, attention, visuospatia…
Sponsor: China Medical University, China • Aim: Symptom relief
Last updated Jul 09, 2026 00:00 UTC
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Enzyme injection could loosen stiff joints in brain and spinal cord injuries
Symptom relief Not yet recruitingThe overall goal is to investigate the effectiveness of a novel intervention - Collagenase injection, for contracture management in patients with neurological impairments, such as stroke, brain injury, and spinal cord injury.
Early phase 1 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Retraining the brain to value food: a new approach for anorexia
Knowledge-focused Not yet recruitingThe goal of this clinical trial is to examine whether food value construction can be biased in individuals with anorexia nervosa. The main question it aims to answer is: Can a simple training task increase the importance of relevant food attributes such that subsequent choices a…
Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Wearable sleep trackers reveal how Weight-Loss surgery changes rest
Knowledge-focused Not yet recruitingObesity is frequently associated with sleep disturbances, including poor sleep quality, insomnia symptoms, daytime sleepiness, and obstructive sleep apnea. Metabolic surgery is an effective treatment for obesity and may improve several sleep-related outcomes, but the long-term ch…
Sponsor: Catharina Ziekenhuis Eindhoven • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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Guiding survivors: navigation program aims to boost access to supportive care
Symptom relief Recruiting nowThis clinical trial studies whether a navigation program improves survivorship support service participation among survivors of breast cancer that has not spread from where it first started (primary site) to other places in the body (non-metastatic). Advances in treatment have ca…
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Aug 16, 2026 00:00 UTC
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Digital tests may offer a new way to track brain health in tumor patients
Knowledge-focused Not yet recruitingThis study is to determine whether self-administered digital cognitive tests can serve as accurate and reliable alternatives to established neuropsychological tests for evaluating cognitive functioning in participants with primary central nervous system lymphoma and low-grade gli…
Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Blood particles may reveal hidden clues to scleroderma complications
Knowledge-focused Not yet recruitingSystemic sclerosis is a multisystem autoimmune disease characterized by vascular dysfunction, immune dysregulation, and progressive tissue fibrosis. Cardiopulmonary complications and peripheral vascular involvement are the principal causes of disability and mortality. Extracellu…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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Wearable sensors aim to catch neurodegenerative decline in real time
Knowledge-focused Not yet recruitingThis is a single-arm, longitudinal, observational study on the use of wearable sensors and digital health technology to measure fall frequency and motor, speech, and cognitive function in patients with PSP over the course of approximately one year. Participants will perform super…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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Does a simple back massage alter brain waves? a trial puts it to the test
Knowledge-focused Not yet recruitingThis study will examine the immediate (acute) effects of a single myofascial release technique applied to the thoracolumbar fascia on brain activity in healthy young adults aged 18-25. Using a sham-controlled, randomized design, participants will be assigned to either an active t…
Sponsor: Hitit University • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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Toothpaste that rebuilds enamel? a lab test pits bioactive glass against resin
Disease control Not yet recruitingThe aim of this in vitro study is to assess the mean lesion depth improvement and hardness of artificial white spot lesions by comparing the effects of bioactive glass toothpaste and resin infiltration (ICON).
Sponsor: Riphah International University • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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Can a simple hole prevent dangerous emboli during bone surgery?
Disease control Not yet recruitingThe purpose of this study is to measure intraoperative embolic burden during prophylactic intramedullary nailing of impending femur fractures in patients treated with versus without venting, to find the association between embolic burden and intraoperative physiologic changes, me…
Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC