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127005 trials found · Page 2491 of 6351
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Gene therapy shot for dry AMD shows promise but trial halted early
Disease control Stopped earlyThe purpose of this clinical study was to evaluate the safety and efficacy of two doses of GT005 administered as a single subretinal injection in subjects with geographic atrophy secondary to age-related macular degeneration (AMD).
Phase 2 • Sponsor: Gyroscope Therapeutics Limited • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Experimental pill ICP-723 enters human trials for Hard-to-Treat cancers
Disease control Recruiting nowA Multicenter, Nonrandomized, Open-Label Phase I/IIClinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of ICP-723 in Patients with Solid Tumors
Phase 1/2 • Sponsor: Beijing InnoCare Pharma Tech Co., Ltd. • Aim: Disease control
Last updated Jun 26, 2026 12:39 UTC
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Can two existing drugs help cancer patients ditch steroids?
Symptom relief OngoingThe purpose of this study is to examine how effective rituximab or tocilizumab are in treating side effects for people who are receiving immunotherapy treatment requiring prolonged steroid use. Immune-related side effects are caused by the activation of the immune system. Becaus…
Phase 2 • Sponsor: Columbia University • Aim: Symptom relief
Last updated Aug 05, 2026 00:00 UTC
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Could farm animals help young adults with autism break out of social isolation?
Symptom relief OngoingNeuropsychiatric impairments in young adults are common and can involve social withdrawal, and difficulties in receiving support from healthcare and municipal social care services. Collaboration is needed, but knowledge gaps exist concerning effective interventions. Participation…
Sponsor: Kronoberg County Council • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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Can emotional distress shape Ovarian-Sparing surgery choices?
Knowledge-focused OngoingThe purpose of this study is to learn more about the factors that influence decision-making before surgery (distress about cancer and/or reproductive concerns) and the possibility of regret after surgery.
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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New study probes immune changes in bladder cancer before surgery
Knowledge-focused OngoingThis is an open-label, window of opportunity platform study for subjects with muscle-invasive bladder cancer (MIBC) who are deemed ineligible or refuse cisplatin-based neoadjuvant chemotherapy and are scheduled to undergo definitive surgery (radical cystectomy), or are planning t…
Phase 2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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New radiation technique aims to safely prepare blood cancer patients for transplant
Disease control CompletedSingle institution study of safety of linac based VMAT TBI for myeloablative treatment in hematologic malignancies.
Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Can extra protein save lives in the ICU?
Disease control Recruiting nowThe investigator will investigate the effect of supplemental enteral protein (1.2 g/kg/day) added to standard formula to achieve high amount of enteral protein (range 2-2.4 g/kg/day) given from ICU day 5 until ICU discharge up to ICU day 90 as compared to no supplemental enteral …
Sponsor: King Abdullah International Medical Research Center • Aim: Disease control
Last updated Jun 26, 2026 15:06 UTC
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Plasma from recovered patients tested against COVID-19 – trial ends early
Disease control Stopped earlyA prospective, randomized, placebo-controlled, double-blinded, phase III clinical trial of the therapeutic use of convalescent plasma in the treatment of patients with moderate to severe COVID-19
Phase 3 • Sponsor: South African National Blood Service • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Can meditation rewire brain networks? scientists scan for answers
Knowledge-focused CompletedThe purpose of this study is to investigate functional brain network in altered meditation state with multimodal neuroimaging.
Sponsor: Shanghai Mental Health Center • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC
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Could probiotics help tame fatty liver?
Disease control CompletedA study for evaluating the improvement effect on Metabolic dysfunction-associated steatotic liver disease (MASLD) of probiotics Metabolic dysfunction-associated steatotic liver disease (MASLD) is associated with dysbiosis of the gut microbiota and altered host metabolic homeosta…
Phase 1/2 • Sponsor: Chuncheon Sacred Heart Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New cancer drug shows promise in early safety trial
Disease control CompletedA phase I dose escalation and cohort expansion study to evaluate the safety, tolerance and pharmacokinetic of BAT1308 injection in patients with advanced solid tumors
Phase 1 • Sponsor: Bio-Thera Solutions • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Could a gene mutation predict immunotherapy success? virtual trial aims to find out
Knowledge-focused OngoingThis study is being done to see if patients with metastatic solid tumors (hematologic malignancies and lymphoma excluded) who have a specific genetic mutation in patients' tumor (the SF3B1, U2AF1 or SRSF2 mutation), are more likely to respond to immunotherapy agents that are now …
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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Cancer patients may skip hospital stays with new home care program
Symptom relief OngoingThis research study is evaluating a program that entails remote monitoring and home-based care for people with cancer who are receiving chemotherapy, radiotherapy, or chemoradiotherapy.
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New combo aims to tackle tough prostate cancer
Disease control OngoingThis is a phase 1, open label, prospective, non-randomized single arm study combining Radium-223 with nivolumab in men with metastatic castration resistant prostate cancer.
Phase 1 • Sponsor: University of Utah • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New online tool aims to ease breast cancer symptoms for young women
Symptom relief OngoingThis research study is being done to monitor common symptoms and behavior, and to provide supportive care information and peer support, as well as research opportunities for young women ages of 18-39 years old who have been diagnosed with stage 0-IV stage breast cancer using a we…
Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Could a simple quiz match you to the perfect back pain exercise?
Knowledge-focused CompletedExercise therapy is the most recommended treatment for chronic low back pain. There is a wide range of exercises available and research studies have shown that no exercise is superior to another. The problem is that the effects of exercise in reducing pain and disability are smal…
Sponsor: McMaster University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Can smartphones and wearables unlock the secrets of atrial fibrillation?
Knowledge-focused By invitation onlyAtrial fibrillation (also known as AFib or AF) is the most common abnormal heart rhythm and results in an irregular beating of the heart. Currently, there is no way of identifying patients at most risk for the development or progression of AFib or those that will best respond to …
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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App-Based monitoring shows promise for IBD patients
Disease control CompletedM-TECCU is a study: multicenter, randomized and open. It consists of two parallel groups to compare the efficacy of the TECCU web-based telemonitoring system to achieve and maintain activity remission in patients with moderate-high complexity inflammatory bowel disease compared t…
Sponsor: Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New radiation approach aims to tame pituitary tumors with fewer side effects
Disease control CompletedSingle session stereotactic radiosurgery (SRS) is commonly used for patients with non-functioning adenomas. However the SRS can be limited by the proximity of the tumor with the surrounding critical structures (i.e., the optic chiasm). The goal of the present prospective phase I…
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC