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127005 trials found · Page 2298 of 6351
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Can a family-focused lifestyle program help teens avoid obesity and diabetes?
Disease control OngoingThe overarching goal of this work is to address the limited access to evidence-based health behavior and lifestyle interventions for youth and families most impacted by preventable chronic diseases, including obesity and type 2 diabetes. In the current project, we implement a sma…
Sponsor: Colorado State University • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Blood test could replace biopsies for breast cancer subtyping
Diagnosis Recruiting nowThe goal of this observational study is to learn if a new diagnostic test using specific labels for breast cancer sEVs on a microchip can accurately diagnose the molecular subtypes in patients with breast cancer. The main questions it aims to answer are: * What is the sensitivit…
Sponsor: Fudan University • Aim: Diagnosis
Last updated Jun 27, 2026 12:31 UTC
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Can fun and games sharpen young minds? study tests playful exercise for school readiness
Knowledge-focused CompletedExecutive functions, such as attention, inhibition, working memory, and planning, are important for early learning and school readiness in preschool children. This completed randomized controlled trial evaluated whether an 8-week cognitively enriched playful physical activity pro…
Sponsor: Inonu University • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Could a daily electrolyte tablet revive Women's energy and hydration?
Symptom relief CompletedThis study evaluates the effects of the Daily Love Electrolytes supplement on women's wellness over a 4-week period. The primary focus is on perceived hydration and energy levels, assessed via self-reported questionnaires at Baseline, Week 1, Week 2, Week 3, and Week 4. This is …
Sponsor: Love Wellness • Aim: Symptom relief
Last updated Aug 16, 2026 00:00 UTC
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Could an arthritis drug help kids with duchenne MD? new trial aims to find out
Disease control OngoingThe purpose of this study is to assess the efficacy, safety, pharmacokinetics (PK) and pharmacodynamics (PD) of satralizumab, a humanized anti-interleukin-6 receptor (aIL-6R) monoclonal antibody, in ambulatory and non-ambulatory participants with DMD aged ≥ 8 to \< 18 years old r…
Phase 2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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A Child's saliva may hold the secret to cavity risk
Knowledge-focused Recruiting nowThe goal of this observational study is to learn if the composition of salivary proteins in 3-year-old children, from communities with documented varying caries risks, can be used to identify future diagnostic predictors for caries risk. The main question to answer is: • Can th…
Sponsor: Karolinska Institutet • Aim: Knowledge-focused
Last updated Aug 07, 2026 00:00 UTC
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New combo pill aims to lower cholesterol in phase 3 trial
Disease control CompletedA Multi-center, Randomized, Double-blind, Parallel, Phase Ⅲ Clinical Trial to Evaluate the Efficacy and Safety of Co-administration of JW0108+C2407 in Patients with Dyslipidemia
Phase 3 • Sponsor: JW Pharmaceutical • Aim: Disease control
Last updated Jun 26, 2026 13:22 UTC
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New drug raphamin aims to speed relief from sinus infection symptoms
Symptom relief Recruiting nowMulticenter double-blind placebo-controlled randomized in parallel groups clinical trial of the efficacy and safety of Raphamin in the treatment of acute rhinosinusitis in adult patients.
Phase 3 • Sponsor: Materia Medica Holding • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Could extra oxygen during surgery prevent wound infections?
Disease control CompletedSurgical site infections (SSI) are the most common healthcare-associated infections and sources of morbidity and over-mortality. Factors that have been proven to reduce SSI include antimicrobial prophylaxis, maintenance of perioperative normothermia, avoidance of hyperglycemia, p…
Sponsor: Assiut University • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Can special lenses slow eye growth in nearsighted kids?
Knowledge-focused CompletedThe goal of this clinical trial is to learn how children with myopia aged 8 to 15 years move their eyes and heads during near-vision tasks while wearing different spectacle lenses, and if wearing myopia control spectacle lenses for one month is related to change in eye length (ax…
Sponsor: Essilor International • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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New drug combo targets breathing pauses in sleep apnea
Symptom relief OngoingThe primary purpose of this study is to evaluate the effectiveness of sivopixant, acetazolamide and SASS-001 in adults with sleep apnea with a central component.
Phase 2 • Sponsor: Shionogi • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New drug HCB301 enters early human trials for tough cancers
Disease control Recruiting nowThe purpose of this study is to find out whether IV injection of HCB301 is an effective treatment for different types of advanced solid tumors and relapsed and refractory classical Hodgkin lymphomas and what side effects (unwanted effects) may occur in subjects aged 18 years old …
Phase 1 • Sponsor: FBD Biologics Limited • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New sedative could help ventilator patients breathe easier
Disease control Recruiting nowThe goal of this clinical trial is to evaluate the effect of remimazolam sedation on outcomes of mechanically ventilated ICU patients through a single-center, prospective, randomized controlled, pilot study.
Phase 3 • Sponsor: Southeast University, China • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Massive trial aims to settle debate: which common surgery drug saves kidneys?
Disease control Recruiting nowLow blood pressure, also known as hypotension, is very common during major surgery under general anesthesia. Prolonged or severe hypotension can lead to complications such as kidney injury after surgery that slow down patient recovery. Anesthesiologists commonly administer medica…
Phase 4 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Can arginine and glutamine soothe radiation mouth pain?
Symptom relief CompletedThis triple-blinded, randomized controlled clinical trial investigates the effectiveness of L-arginine and L-glutamine oral suspensions in managing radiation-induced oral mucositis (RIOM) in patients with head and neck cancer (HNC) undergoing radiotherapy. A total of 69 patients …
Phase 2 • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Student pharmacists may hold the key to better diabetes control in older asian adults
Disease control CancelledThis study is being done to assess the impact of student pharmacist involvement on blood glucose control through non-pharmacological interventions in people of Asian and Asian descent over the age of 50 with type 2 diabetes. This study team is trying to advance the field of pharm…
Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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Quick therapy vs. waiting: does faster help for anxiety and depression pay off?
Symptom relief Recruiting nowThe primary aim of "the Effectiveness of Psychological Interventions for Common mental disorders" (EPIC) randomized controlled trial is to investigate whether a significantly larger symptom improvement is observed after approximately four months of psychotherapeutic treatment in …
Sponsor: University of Copenhagen • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Can a new tooth filling make Kids' cavity repairs last longer?
Disease control CompletedIs zirconomer restorative material more effective than a glass ionomer cement in restoration of primary molars
Sponsor: Cairo University • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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New cancer cocktail enters human testing
Disease control Recruiting nowThe main purpose of this study is to evaluate the safety and preliminary efficacy of CHS-114 in combination with toripalimab and/or other standard of care (SOC) compound(s) in participants with advanced or metastatic solid tumors.
Phase 1 • Sponsor: Coherus Oncology, Inc. • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Structured exercise may improve PCOS symptoms, small trial suggests
Disease control OngoingDesign: RCT Randomized Clinical Trial Non Probability Convenient Sampling Technique Duration of treatment: 25 weeks 2 groups; (group A=30) SSAET +Normal routine medication+ Normal Dietary Plan , Other group (Group B=30) with normal routine medication + Normal Dietary Plan. Patie…
Sponsor: Riphah International University • Aim: Disease control
Last updated Jun 26, 2026 13:30 UTC