A Child's saliva may hold the secret to cavity risk

NCT ID NCT06957509

Recruiting now Knowledge-focused Sponsor: Karolinska Institutet Source: ClinicalTrials.gov ↗

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This study looks at whether the proteins in the saliva of 3-year-old children can help predict their risk of developing early childhood caries (cavities). Researchers will compare saliva samples and dental exams from children in two different communities in Stockholm, Sweden, to see if protein patterns differ based on cavity prevalence. The goal is to find potential biomarkers that could lead to a simple diagnostic tool for early cavity risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple saliva test to identify young children at high risk for cavities, enabling earlier prevention.
What could go wrong: This is an observational study, so it cannot prove cause and effect. The findings may not apply to other populations, and the protein markers may not be reliable enough for clinical use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EARLY CHILDHOOD CARIES (ECC)

Contacts and locations

Locations

Folktandvården Stockholms län AB
RECRUITING

Stockholm, Sweden

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