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116076 trials found · Page 2091 of 5804
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Can gut bacteria predict celiac disease? new study follows At-Risk infants
Knowledge-focused Recruiting nowCeliac disease (CD) is a complex disease caused by eating gluten, a protein contained in wheat, rye, and barley. It is well known that many factors contribute to the development of CD, including the genes that you have and the foods that you eat. In the CDGEMM study, we will cons…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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PET-CT scans could sharpen radiation targeting for liver tumors
Knowledge-focused CompletedThis clinical trial studies positron emission tomography (PET)-computed tomography (CT) in determining the radiation dose delivered with radioactive spheres to patients with liver metastasis or primary liver or biliary cancer. Comparing results of diagnostic procedures dose befor…
Phase: NA • Sponsor: Fox Chase Cancer Center • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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One-Time radiation blast shows promise for prostate cancer
Disease control CompletedRecently, HDR brachytherapy delivering only a 19 Gy fraction was proposed as exclusive treatment for low and intermediate risk prostate cancers. With a median 3-year follow-up, the Spanish team reported a biochemical control rate of 100% and 87%, respectively, for low risk and in…
Phase: NA • Sponsor: Centre Antoine Lacassagne • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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AI model aims to predict diabetes foot ulcers before they start
Knowledge-focused Recruiting nowIntroduction Foot ulcers in diabetes mellitus (DM) are a common and serious complication that can lead to infection, amputation, and increased mortality. Early identification of patients at high risk is crucial in order to implement preventive measures at an early stage. The numb…
Sponsor: Sahlgrenska University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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New hope for MSA patients: drug may reduce dizzy spells and falls
Symptom relief CompletedEvaluate the effects of L-Threo DOPS on orthostatic hypotension symptoms and other non-motor symptoms in patients with Multiple System Atrophy (MSA) after 12 weeks following randomization to continued therapy with droxidopa or placebo.
Phase: PHASE2, PHASE3 • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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New balloon treatment for heart disease under Real-World study
Disease control Recruiting nowThe purpose of this study is to evaluate long-term effectiveness and safety of patients with coronary disease treated with drug eluting balloon in real world practice.
Sponsor: Seung-Jung Park • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New tube system could make dialysis access easier for kidney patients
Disease control CompletedThe objective of this study is to evaluate the safety and efficacy of the FLEX System when used to create an arteriovenous fistula (AVF or AV fistula) percutaneously in patients with Chronic Kidney Disease (CKD) who require hemodialysis vascular access.
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Coordinated care after a fracture could stop the next one
Disease control OngoingAims: to Establish the FLS services at the National Taiwan University Hospital (NTUH) and its Beihu Branch (BB). Method: From Jan., 2014, two related fracture liaison services (FLSs) following the 13 'Capture the Fracture Best Practice Standards' were implemented at the National…
Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Which radiation boost is better for prostate cancer? new trial aims to find out
Disease control OngoingOptimal non surgical treatment of prostate cancer requires dose escalation which is frequently provided by adding a brachytherapy "boost" to a short course of external beam radiotherapy. The hypothesis in this randomized study is that a High Dose Rate (HDR) brachytherapy boost le…
Phase: NA • Sponsor: British Columbia Cancer Agency • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Can a calming drug combo bring clarity to cancer patients?
Symptom relief OngoingThis randomized phase II trial studies how well haloperidol with or without lorazepam works in reducing confusion, disorientation, and inability to think or remember clearly (delirium) in patients with cancer that has spread to other places in the body and usually cannot be cured…
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jul 19, 2026 00:00 UTC
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Surgery offers new hope for chronic pain sufferers
Symptom relief CompletedThis clinical study evaluates the effectiveness of surgical treatment in patients with upper-limb complex regional pain syndrome (CRPS) diagnosed according to the Budapest criteria. Seventy-four patients were assessed between 2014 and 2023. Patients with identifiable structural p…
Phase: NA • Sponsor: Jitka Fricova • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Promising combo for Hard-to-Treat breast cancer hits snag, trial halted
Disease control TerminatedThe overall rationale of this study evaluating tolerance and efficacy of LY2780301 in combination with paclitaxel in HER2-negative, inoperable locally advanced or metastatic breast cancer (MBC) is based on : * the medical need in this population with either hormonal-resistant or…
Phase: PHASE1, PHASE2 • Sponsor: Institut Paoli-Calmettes • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Built-In eye scanner could give surgeons a live 3D view during operations
Knowledge-focused Recruiting nowOptical coherence tomography (OCT )provides high resolution information regarding the anatomic structure of the tissues of the eye in a cross-sectional and 3 dimensional view. Much of this information is not able to be visualized by a clinician. Utilizing this information during …
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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New drug cuts chemotherapy side effect by over 60% in breast cancer patients
Disease control CompletedThe goal of this clinical trial is to learn if Naderin works to prevent low white blood cell counts in people with breast cancer receiving first-line chemotherapy. The main questions it aims to answer are: 1. Does taking Naderin lower the number of people who get low white blood…
Phase: PHASE2, PHASE3 • Sponsor: MIPO Clinic • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New PET scan may sharpen radiation targeting for brain cancer patients
Knowledge-focused CompletedThis phase II trial studies how well fluorine F 18 fluorodopa (18F-DOPA)-positron emission tomography (PET) works in finding tumors in patients with newly diagnosed gliomas undergoing radiation therapy. Comparing results of diagnostic procedures done before and during radiation t…
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Tailored chemo regimens tested for frail ovarian cancer patients
Disease control CompletedThe current standard of first-line chemotherapy in advanced ovarian cancer is the combination of carboplatin AUC 5mg/mL/min and paclitaxel 175 mg.m-². This combination is feasible in selected elderly patients such as those included in prospective trials. These trials, however, in…
Phase: PHASE2 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Massive study aims to perfect testicular cancer aftercare
Knowledge-focused Recruiting nowThe majority of testicular cancer patients can be cured with cisplatin-based chemotherapy. Mortality has been reduced even more within the last 15 years due to the stringent application of standard chemotherapy followed by resection of residual disease. This is a positive develop…
Sponsor: Dr. med. Christian Rothermundt • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Can we predict who will thrive with brain stimulation for Parkinson's?
Knowledge-focused CompletedThis study identify preoperative predictors of response to subthalamic stimulation at 1 year, 3 years and 5 years in terms of quality of life, from a broad prospective multicenter study French with standardized collection of clinical data , imaging and genetic . The investigator…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New knee implant tracked for 5 years in 777 patients
Disease control OngoingThe primary objective of this study is to obtain implant survivorship and clinical outcomes data for commercially available Persona knee implants used in primary total knee arthroplasty. The assessment will include: 1. Implant survivorship based on removal of a study device. 2. …
Sponsor: Zimmer, GmbH • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Brain scan breakthrough: new MRI method could spot autism in kids
Diagnosis CompletedThe purpose of this study is reproduce the individual detection results by PET with Arterial Spin Labeling (ASL) MRI, to establish a biomarker useful in autism diagnosis.
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC