New drug duo shows promise for hard-to-treat blood cancer

NCT ID NCT02942290

First seen May 21, 2026 · Last updated May 21, 2026

Summary

This early-stage study tests a combination of two drugs, venetoclax and azacitidine, in people with a serious form of myelodysplastic syndromes (MDS) who have not had prior treatment. The goal is to find the safest dose and see how well the drugs work together to control the disease. About 129 adults with higher-risk MDS are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Austin Health /ID# 154955

    Heidelberg, Victoria, 3084, Australia

  • Calvary Mater Newcastle /ID# 154957

    Waratah, New South Wales, 2298, Australia

  • Centre Hospitalier Universitaire de Nantes, Hotel Dieu -HME /ID# 153828

    Nantes, Pays de la Loire Region, 44000, France

  • Columbia University Medical Center /ID# 153661

    New York, New York, 10032-3729, United States

  • Concord Repatriation General Hospital /ID# 154958

    Concord, New South Wales, 2139, Australia

  • Dana-Farber Cancer Institute /ID# 152735

    Boston, Massachusetts, 02215, United States

  • Duplicate_Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 153764

    Rome, Roma, 00161, Italy

  • Duplicate_IRCCS AOU di Bologna - Policlinico Sant'Orsola-Malpighi /ID# 153763

    Bologna, Emilia-Romagna, 40138, Italy

  • Duplicate_Princess Alexandra Hospital /ID# 154990

    Woolloongabba, Queensland, 4102, Australia

  • Duplicate_St. Vincent's Hospital, Darlinghurst /ID# 222846

    Darlinghurst, New South Wales, 2010, Australia

  • Duplicate_Universitaetsklinikum Carl Gus /ID# 153958

    Dresden, Saxony, 01307, Germany

  • Duplicate_University of Arizona Cancer Center - North Campus /ID# 154155

    Tucson, Arizona, 85719-1478, United States

  • Fiona Stanley Hospital /ID# 222847

    Murdoch, Western Australia, 6150, Australia

  • Hôpital Saint-Louis /ID# 153827

    Paris, 75010, France

  • Juravinski Cancer Centre /ID# 152947

    Hamilton, Ontario, L8V 1C3, Canada

  • King's College Hospital NHS Foundation Trust /ID# 156489

    London, SE5 9RS, United Kingdom

  • Klinikum rechts der Isar /ID# 153139

    Munich, Bavaria, 81675, Germany

  • Liverpool Hospital /ID# 222410

    Liverpool, New South Wales, 2170, Australia

  • Norfolk and Norwich University Hospitals NHS Foundation Trust /ID# 156492

    Norwich, Norfolk, NR4 7UY, United Kingdom

  • Oregon Medical Research Center /ID# 152734

    Portland, Oregon, 97239, United States

  • Oxford University Hospitals NHS Foundation Trust /ID# 222567

    Oxford, Oxfordshire, OX3 9DU, United Kingdom

  • St George Hospital /ID# 154954

    Kogarah, New South Wales, 2217, Australia

  • Tennessee Oncology-Nashville Centennial /ID# 222769

    Nashville, Tennessee, 37203-1632, United States

  • The Alfred Hospital /ID# 154956

    Melbourne, Victoria, 3004, Australia

  • The University of Chicago Medical Center /ID# 153673

    Chicago, Illinois, 60637-1443, United States

  • Tufts Medical Center /ID# 153672

    Boston, Massachusetts, 02111-1552, United States

  • UT MD Anderson Cancer Center /ID# 153809

    Houston, Texas, 77030, United States

  • Universitaetsklinikum Halle (Saale) /ID# 153760

    Halle, 06120, Germany

  • Universitaetsklinikum Koeln /ID# 153141

    Cologne, North Rhine-Westphalia, 50937, Germany

  • Universitaetsklinikum Leipzig /ID# 153142

    Leipzig, Saxony, 04103, Germany

  • Universitatsklinikum Mannheim /ID# 153140

    Mannheim, Baden-Wurttemberg, 68167, Germany

  • University Hospitals Birmingham NHS Foundation Trust /ID# 158810

    Birmingham, B15 2TH, United Kingdom

  • University of Maryland, Baltimore /ID# 153669

    Baltimore, Maryland, 21201, United States

  • University of Pittsburgh MC /ID# 153662

    Pittsburgh, Pennsylvania, 15260, United States

  • Vanderbilt University Medical Center /ID# 152738

    Nashville, Tennessee, 37232-0011, United States

  • Washington University-School of Medicine /ID# 153671

    St Louis, Missouri, 63110, United States

  • Weill Cornell Medical College /ID# 155524

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.