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School Stress-Busting program for LGBTQ teens shows promise, but study cut short

NCT ID NCT05541406

Symptom relief Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 3 times

Summary

This study tested a school-based program called Proud & Empowered, designed to help LGBTQ students cope with minority stress and improve mental health. About 228 high school students took part. The program was led by school counselors and social workers. The study was terminated early, so we have less information than planned, but the goal was to reduce depression, anxiety, PTSD, and suicide risk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Proud & Empowered school-based behavioral program
What this could lead to
If effective, this program could provide schools with a practical way to support LGBTQ students' mental health and reduce stress-related harms.
What could go wrong
The study was terminated early, so results are limited. It is unclear if the program works better than usual school support, and findings may not apply to all schools or regions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 228 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2022

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

12 to 20 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * LGBTQ student in one of 24 high schools Exclusion Criteria: * Not meeting inclusion criteria

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Bullying Depression depressive disorder post-traumatic stress disorder substance abuse substance-related disorder Suicidal Ideation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety Bullying Coping behavior Depression Harassment Post-traumatic stress disorder Sexual minority stress Substance use Suicidality

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Anderson W. Clark Magnet High School

    COMPLETED

    Glendale, California, 91214, United States

  • Animo Leadership High School

    COMPLETED

    Inglewood, California, 90304, United States

  • Animo Pat Brown Charter High School

    COMPLETED

    Los Angeles, California, 90001, United States

  • Arroyo High School

    COMPLETED

    El Monte, California, 91732, United States

  • Blair High School

    COMPLETED

    Pasadena, California, 91106, United States

  • Brio College Prep

    COMPLETED

    Los Angeles, California, 90071, United States

  • Crescenta Valley High School

    COMPLETED

    La Crescenta-Montrose, California, 91214, United States

  • El Monte High School

    COMPLETED

    El Monte, California, 91731, United States

  • Fernando R Ledesma High School

    COMPLETED

    El Monte, California, 91732, United States

  • Inglewood High School

    COMPLETED

    Inglewood, California, 90303, United States

  • Larchmont Charter School

    COMPLETED

    Los Angeles, California, 90057, United States

  • Lynwood High School

    COMPLETED

    Lynwood, California, 90262, United States

  • Marco Antonio Firebaugh High School

    COMPLETED

    Lynwood, California, 90262, United States

  • Marshall Fundamental Secondary School

    COMPLETED

    Pasadena, California, 91104, United States

  • Millikan High School

    COMPLETED

    Long Beach, California, 90815, United States

  • Mountain View High School

    COMPLETED

    El Monte, California, 91732, United States

  • Pasadena High School

    COMPLETED

    Pasadena, California, 91107, United States

  • Rosemead High School

    COMPLETED

    Rosemead, California, 91770, United States

  • South El Monte High School

    COMPLETED

    El Monte, California, 91733, United States

  • South LA College Prep

    COMPLETED

    Los Angeles, California, 90044, United States

  • USC Hybrid High School

    COMPLETED

    Los Angeles, California, 90037, United States

  • Vista High School

    COMPLETED

    Lynwood, California, 90262, United States

  • Washington University in St. Louis

    RECRUITING

    St Louis, Missouri, 63130, United States

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