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New hope for rare cancers: immunotherapy drug targets tumors regardless of origin

NCT ID NCT06638931

First seen Apr 23, 2026 · Last updated Jun 17, 2026 · Updated 8 times

Summary

This study tests the drug nivolumab in people with advanced rare cancers that have a specific marker (PD-L1). The goal is to see if the drug can shrink or control the tumors when other treatments have stopped working. Up to 28 adults will receive treatment for up to 12 months, and researchers will monitor how well the cancer responds.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • DF Star

    NOT_YET_RECRUITING

    Brasília, 70390-903, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Santa Cruz

    NOT_YET_RECRUITING

    Curitiba, Paraná, 80420-090, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital São Carlos

    NOT_YET_RECRUITING

    Fortaleza, Ceará, 60170-170, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital São Rafael

    NOT_YET_RECRUITING

    Salvador, Estado de Bahia, 41253-190, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IDOR Recife

    NOT_YET_RECRUITING

    Recife, Pernambuco, 52010-010, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instituto D'Or de Pesquisa e Ensino

    NOT_YET_RECRUITING

    Rio de Janeiro, 22281-100, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instituto D'or de Pesquisa e Ensino

    RECRUITING

    São Paulo, São Paulo, 04.501-000, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Instituto do Câncer do Estado de São Paulo - ICESP

    RECRUITING

    São Paulo, São Paulo, 05403-010, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

adenoid cystic carcinoma adrenal gland cancer adrenal gland neoplasm angiosarcoma anus neoplasm apocrine adenocarcinoma biliary tract neoplasm Biliary Tract Neoplasms bladder urachal adenocarcinoma bladder urachal carcinoma breast secretory carcinoma cancer of unknown primary site Carcinoma, Ovarian Epithelial carcinosarcoma cholangiocarcinoma Endodermal Sinus Tumor endometrial clear cell adenocarcinoma fallopian tube neoplasm fibrolamellar hepatocellular carcinoma fibrosarcoma gallbladder neoplasm granulosa cell tumor hemangioblastoma hepatoblastoma Kaposi's sarcoma leiomyosarcoma mesothelioma metaplastic breast carcinoma MIT family translocation renal cell carcinoma neuroblastoma Neuroectodermal Tumors, Primitive neuroendocrine neoplasm neurofibrosarcoma osteosarcoma ovarian carcinoma parathyroid gland carcinoma Parathyroid Neoplasms penile neoplasm primitive neuroectodermal tumor sarcoma Sertoli-Leydig cell tumor small intestine neoplasm soft tissue sarcoma Thyroid Neoplasms thyroid tumor trophoblastic neoplasm urachus cancer urethra neoplasm Urethral Neoplasms vaginal cancer vaginal neoplasm vulva cancer vulvar neoplasm yolk sac tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.